6VVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vvu by Molmil](/molmil-images/mine/6vvu) | Anti-Tryptase fab E104.v1 bound to tryptase | Descriptor: | CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ... | Authors: | Ultsch, M, Koerber, J.T. | Deposit date: | 2020-02-18 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge. Nat Commun, 11, 2020
|
|
6VVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vvo by Molmil](/molmil-images/mine/6vvo) | Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. | Deposit date: | 2020-02-18 | Release date: | 2020-02-26 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
|
|
5R42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r42 by Molmil](/molmil-images/mine/5r42) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 7.5, room temperature | Descriptor: | IODIDE ION, gamma-Chymotrypsin, peptide SWPW, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r49 by Molmil](/molmil-images/mine/5r49) | Crystal Structure of gamma-Chymotrypsin at pH 5.6, cryo temperature | Descriptor: | IODIDE ION, MALONATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R45
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r45 by Molmil](/molmil-images/mine/5r45) | Crystal Structure of gamma-Chymotrypsin at pH 7.5, cryo temperature | Descriptor: | Chymotrypsinogen A, IODIDE ION, MALONATE ION, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r4c by Molmil](/molmil-images/mine/5r4c) | Crystal Structure of gamma-Chymotrypsin at pH 9, room temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r48 by Molmil](/molmil-images/mine/5r48) | Crystal Structure of gamma-Chymotrypsin at pH 5.6, room temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R4A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r4a by Molmil](/molmil-images/mine/5r4a) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 9, room temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r44 by Molmil](/molmil-images/mine/5r44) | Crystal Structure of gamma-Chymotrypsin at pH 7.5, room temperature | Descriptor: | Chymotrypsinogen A, IODIDE ION, peptide SWPW, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R46
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r46 by Molmil](/molmil-images/mine/5r46) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 5.6, room temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r43 by Molmil](/molmil-images/mine/5r43) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 7.5, cryo temperature | Descriptor: | Chymotrypsinogen A, IODIDE ION, MALONIC ACID, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r4b by Molmil](/molmil-images/mine/5r4b) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 9, cryo temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r4d by Molmil](/molmil-images/mine/5r4d) | Crystal Structure of gamma-Chymotrypsin at pH 9, cryo temperature | Descriptor: | IODIDE ION, SULFATE ION, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
5R47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r47 by Molmil](/molmil-images/mine/5r47) | Crystal Structure of deuterated gamma-Chymotrypsin at pH 5.6, cryo temperature | Descriptor: | IODIDE ION, MALONIC ACID, gamma-chymotrypsin, ... | Authors: | Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D. | Deposit date: | 2020-02-18 | Release date: | 2021-09-01 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study To be published
|
|
6Y2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y2o by Molmil](/molmil-images/mine/6y2o) | Crystal structure of the cAMP-dependent protein kinase A cocrystallized with 1,7-Naphthyridin-8-amine and PKI (5-24) | Descriptor: | 1,7-naphthyridin-8-amine, DIMETHYL SULFOXIDE, cAMP-dependent protein kinase catalytic subunit alpha, ... | Authors: | Oebbeke, M, Heine, A, Klebe, G. | Deposit date: | 2020-02-17 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Fragment based drug design - Small chemical changes of fragments effecting big changes in binding To Be Published
|
|
6Y2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y2u by Molmil](/molmil-images/mine/6y2u) | Crystal structure of the cAMP-dependent protein kinase A cocrystallized with aminofasudil and PKI (5-24) | Descriptor: | 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | Authors: | Oebbeke, M, Gerber, H.-D, Heine, A, Klebe, G. | Deposit date: | 2020-02-17 | Release date: | 2021-03-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Fragment based drug design - Small chemical changes of fragments effecting big changes in binding To Be Published
|
|
6VVG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vvg by Molmil](/molmil-images/mine/6vvg) | Structure of the Cydia pomonella Granulovirus kinase, PK-1 | Descriptor: | ADENOSINE MONOPHOSPHATE, Arginine kinase | Authors: | Oliver, M.R, Horne, C.R, Keown, J.R, Murphy, J.M, Metcalf, P. | Deposit date: | 2020-02-17 | Release date: | 2021-02-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory alpha C helix. Nat Commun, 12, 2021
|
|
6LYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lyw by Molmil](/molmil-images/mine/6lyw) | Structural insight into the biological functions of Arabidopsis thaliana ACHT1 | Descriptor: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | Authors: | Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M. | Deposit date: | 2020-02-16 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
|
|
6LYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lyx by Molmil](/molmil-images/mine/6lyx) | Crystal structure of oxidized ACHT1 | Descriptor: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | Authors: | Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M. | Deposit date: | 2020-02-16 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.696 Å) | Cite: | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
|
|
6Y2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y2c by Molmil](/molmil-images/mine/6y2c) | Crystal structure of the third KH domain of FUBP1 | Descriptor: | 1,2-ETHANEDIOL, Far upstream element-binding protein 1, ZINC ION | Authors: | Ni, X, Joerger, A.C, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-15 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1. Sci Rep, 10, 2020
|
|
6Y2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y2d by Molmil](/molmil-images/mine/6y2d) | Crystal structure of the second KH domain of FUBP1 | Descriptor: | Far upstream element-binding protein 1, GLYCEROL, SULFATE ION | Authors: | Ni, X, Chaikuad, A, Joerger, A.C, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-15 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1. Sci Rep, 10, 2020
|
|
6VUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vug by Molmil](/molmil-images/mine/6vug) | |
6Y24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y24 by Molmil](/molmil-images/mine/6y24) | Crystal structure of fourth KH domain of FUBP1 | Descriptor: | 1,2-ETHANEDIOL, Far upstream element-binding protein 1 | Authors: | Ni, X, Joerger, A.C, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-14 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1. Sci Rep, 10, 2020
|
|
5R1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r1t by Molmil](/molmil-images/mine/5r1t) | PanDDA analysis group deposition -- Endothiapepsin in complex with fragment F2X-Entry A07, DMSO-free | Descriptor: | (2-aminopyridin-3-yl)methanol, Endothiapepsin | Authors: | Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. | Deposit date: | 2020-02-13 | Release date: | 2020-06-03 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (1.187 Å) | Cite: | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
|
|
5R28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r28 by Molmil](/molmil-images/mine/5r28) | PanDDA analysis group deposition -- Endothiapepsin in complex with fragment F2X-Entry G08, DMSO-free | Descriptor: | Endothiapepsin, N-ethyl-2-{[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide | Authors: | Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. | Deposit date: | 2020-02-13 | Release date: | 2020-06-03 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (1.019 Å) | Cite: | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
|
|