4X8Q
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![BU of 4x8q by Molmil](/molmil-images/mine/4x8q) | X-ray crystal structure of AlkD2 from Streptococcus mutans | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | Authors: | Mullins, E.A, Shi, R, Eichman, B.F. | Deposit date: | 2014-12-10 | Release date: | 2015-05-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.729 Å) | Cite: | A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases. Plos One, 10, 2015
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6IDG
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![BU of 6idg by Molmil](/molmil-images/mine/6idg) | antibody 64M-5 Fab in complex with dT(6-4)T | Descriptor: | Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), DNA (5'-D(*(64T)P*(5PY))-3') | Authors: | Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N. | Deposit date: | 2018-09-10 | Release date: | 2019-02-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the antibody 64M-5 Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms. Acta Crystallogr.,Sect.F, 75, 2019
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6IKA
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![BU of 6ika by Molmil](/molmil-images/mine/6ika) | HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphate ternary complex | Descriptor: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2018-10-15 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors. Biochem. Biophys. Res. Commun., 509, 2019
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6J8Y
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![BU of 6j8y by Molmil](/molmil-images/mine/6j8y) | Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex | Descriptor: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... | Authors: | Hara, K, Iida, N, Sakurai, H, Hashimoto, H. | Deposit date: | 2019-01-21 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp. J.Biol.Chem., 295, 2020
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3V21
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![BU of 3v21 by Molmil](/molmil-images/mine/3v21) | Crystal structure of Type IIF restriction endonuclease Bse634I with cognate DNA | Descriptor: | DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A)-3'), Endonuclease Bse634IR | Authors: | Manakova, E.N, Grazulis, S, Golovenko, D, Tamulaitiene, G. | Deposit date: | 2011-12-11 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease. Nucleic Acids Res., 40, 2012
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8SZ5
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![BU of 8sz5 by Molmil](/molmil-images/mine/8sz5) | [2T5] Self-assembling DNA motif with 5 base pairs between junctions and P32 symmetry | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*GP*T)-3'), ... | Authors: | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-05-26 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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6HKT
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![BU of 6hkt by Molmil](/molmil-images/mine/6hkt) | Structure of an H1-bound 6-nucleosome array | Descriptor: | DNA (1122-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Garcia-Saez, I, Dimitrov, S, Petosa, C. | Deposit date: | 2018-09-08 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (9.7 Å) | Cite: | Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation. Mol. Cell, 72, 2018
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6HML
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![BU of 6hml by Molmil](/molmil-images/mine/6hml) | POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017299 | Descriptor: | 1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-3-[(1-methylpyrazol-4-yl)methyl]quinazoline-2,4-dione, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Tucker, J.A, Barkauskaite, E. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
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6HMM
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![BU of 6hmm by Molmil](/molmil-images/mine/6hmm) | POLYADPRIBOSYL GLYCOHYDROLASE IN COMPLEX WITH PDD00013907 | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Poly(ADP-ribose) glycohydrolase, ... | Authors: | Tucker, J.A, Brassington, C, Hassall, G. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
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6HMK
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![BU of 6hmk by Molmil](/molmil-images/mine/6hmk) | POLYADPRIBOSYL GLYCOHYDROLASE IN COMPLEX WITH PDD00016690 | Descriptor: | 1-methyl-~{N}-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-bis(oxidanylidene)quinazoline-6-sulfonamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Tucker, J.A, Barkauskaite, E. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
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6HMN
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![BU of 6hmn by Molmil](/molmil-images/mine/6hmn) | POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00014909 | Descriptor: | 3-methyl-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-1-(phenylmethyl)quinazoline-2,4-dione, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Tucker, J.A, Brassington, C, Hassall, G. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
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7XHT
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![BU of 7xht by Molmil](/molmil-images/mine/7xht) | Structure of the OgeuIscB-omega RNA-target DNA complex | Descriptor: | DNA (49-MER), DNA (5'-D(P*GP*AP*AP*GP*AP*AP*AP*AP*CP*CP*AP*T)-3'), LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | Kato, K, Okazaki, O, Isayama, Y, Ishikawa, J, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-04-10 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Structure of the IscB-omega RNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9. Nat Commun, 13, 2022
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6A5K
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![BU of 6a5k by Molmil](/molmil-images/mine/6a5k) | Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4WHV
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![BU of 4whv by Molmil](/molmil-images/mine/4whv) | E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B | Descriptor: | E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-09-23 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (8.3 Å) | Cite: | RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
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6JXD
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![BU of 6jxd by Molmil](/molmil-images/mine/6jxd) | |
7EUC
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![BU of 7euc by Molmil](/molmil-images/mine/7euc) | Parallel G-quadruplex structure | Descriptor: | DNA (5'-D(*TP*TP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*GP*T)-3'), ... | Authors: | Winnerdy, F.R, Devi, G, Ang, J.C.Y, Lim, K.W, Phan, A.T. | Deposit date: | 2021-05-17 | Release date: | 2022-03-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Four-Layered Intramolecular Parallel G-Quadruplex with Non-Nucleotide Loops: An Ultra-Stable Self-Folded DNA Nano-Scaffold. Acs Nano, 16, 2022
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7UYZ
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![BU of 7uyz by Molmil](/molmil-images/mine/7uyz) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | Descriptor: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wu, S, Gabelli, S.B, Sohn, J. | Deposit date: | 2022-05-07 | Release date: | 2023-05-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
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1VTF
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![BU of 1vtf by Molmil](/molmil-images/mine/1vtf) | |
3V1Z
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![BU of 3v1z by Molmil](/molmil-images/mine/3v1z) | Crystal structure of Type IIF restriction endonuclease Bse634I with cognate DNA | Descriptor: | DNA (5'-D(*TP*CP*GP*CP*GP*CP*CP*GP*GP*CP*GP*CP*G)-3'), Endonuclease Bse634IR | Authors: | Manakova, E.N, Grazulis, S, Golovenko, D, Tamulaitiene, G. | Deposit date: | 2011-12-11 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease. Nucleic Acids Res., 40, 2012
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4GIG
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![BU of 4gig by Molmil](/molmil-images/mine/4gig) | |
3L6V
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![BU of 3l6v by Molmil](/molmil-images/mine/3l6v) | Crystal Structure of the Xanthomonas campestris Gyrase A C-terminal Domain | Descriptor: | DNA gyrase subunit A | Authors: | Hsieh, T.J, Yen, T.J, Lin, T.S, Chang, H.T, Huang, S.Y, Farh, L, Chan, N.L. | Deposit date: | 2009-12-26 | Release date: | 2010-03-09 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Twisting of the DNA binding surface by a beta-strand-bearing proline modulates DNA gyrase activity To be Published
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3GZ6
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![BU of 3gz6 by Molmil](/molmil-images/mine/3gz6) | |
1BCE
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![BU of 1bce by Molmil](/molmil-images/mine/1bce) | INTRAMOLECULAR TRIPLEX, NMR, 10 STRUCTURES | Descriptor: | DNA (5'-D(*AP*AP*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*T)-3') | Authors: | Asensio, J.L, Brown, T, Lane, A.N. | Deposit date: | 1998-04-29 | Release date: | 1998-08-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets. Nucleic Acids Res., 26, 1998
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1JYH
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![BU of 1jyh by Molmil](/molmil-images/mine/1jyh) | |
7Y0D
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![BU of 7y0d by Molmil](/molmil-images/mine/7y0d) | |