7XII
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![BU of 7xii by Molmil](/molmil-images/mine/7xii) | Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) & aminopropylagmatine | Descriptor: | 1-{4-[(3-aminopropyl)amino]butyl}guanidine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... | Authors: | Mizohata, E, Yasuda, Y. | Deposit date: | 2022-04-13 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12, 2022
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7XIH
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7XIG
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![BU of 7xig by Molmil](/molmil-images/mine/7xig) | Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) and spermine | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Polyamine aminopropyltransferase, ... | Authors: | Mizohata, E, Yasuda, Y. | Deposit date: | 2022-04-13 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12, 2022
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7XIF
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![BU of 7xif by Molmil](/molmil-images/mine/7xif) | Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) alone or together with spermidine or thermospermine | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, N-(3-AMINO-PROPYL)-N-(5-AMINOPROPYL)-1,4-DIAMINOBUTANE, Polyamine aminopropyltransferase, ... | Authors: | Mizohata, E, Yasuda, Y. | Deposit date: | 2022-04-13 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12, 2022
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7XID
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![BU of 7xid by Molmil](/molmil-images/mine/7xid) | S-ECD (Omicron) in complex with PD of ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2022-04-12 | Release date: | 2022-06-15 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7XIC
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![BU of 7xic by Molmil](/molmil-images/mine/7xic) | S-ECD (Omicron) in complex with STS165 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2022-04-12 | Release date: | 2022-06-15 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7XIB
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![BU of 7xib by Molmil](/molmil-images/mine/7xib) | Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-disordered form) | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*TP*CP*(C55)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | Authors: | Onoda, H, Kikuchi, A, Kori, S, Yoshimi, S, Yamagata, A, Arita, K. | Deposit date: | 2022-04-12 | Release date: | 2022-11-30 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Structural basis for activation of DNMT1. Nat Commun, 13, 2022
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7XI9
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![BU of 7xi9 by Molmil](/molmil-images/mine/7xi9) | Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-ordered form) | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*TP*CP*(C55)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | Authors: | Onoda, H, Kikuchi, A, Kori, S, Yoshimi, S, Yamagata, A, Arita, K. | Deposit date: | 2022-04-12 | Release date: | 2022-11-30 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Structural basis for activation of DNMT1. Nat Commun, 13, 2022
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7XI5
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![BU of 7xi5 by Molmil](/molmil-images/mine/7xi5) | Anti-CRISPR-associated Aca10 | Descriptor: | Transcriptional regulator | Authors: | Lee, S.Y, Park, H.H. | Deposit date: | 2022-04-12 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Molecular basis of anti-CRISPR operon repression by Aca10. Nucleic Acids Res., 50, 2022
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7XI0
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![BU of 7xi0 by Molmil](/molmil-images/mine/7xi0) | Crystal structure of CBP bromodomain liganded with CCS150 | Descriptor: | (6S)-1-(3-chloranyl-4-methoxy-phenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, GLYCEROL | Authors: | Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-04-11 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
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7XHX
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![BU of 7xhx by Molmil](/molmil-images/mine/7xhx) | Crystal structure of metallo-beta-lactamase IMP-6 | Descriptor: | Beta-lactamase, ZINC ION | Authors: | Yamamoto, K, Tanaka, H, Kurisu, G, Nakano, R, Yano, H, Sakai, H. | Deposit date: | 2022-04-11 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-beta-lactamases. J.Biochem., 173, 2022
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7XHW
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![BU of 7xhw by Molmil](/molmil-images/mine/7xhw) | Crystal structure of metallo-beta-lactamase IMP-1 | Descriptor: | Beta-lactamase, ZINC ION | Authors: | Yamamoto, K, Tanaka, H, Kurisu, G, Nakano, R, Yano, H, Sakai, H. | Deposit date: | 2022-04-11 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-beta-lactamases. J.Biochem., 173, 2022
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7XHU
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![BU of 7xhu by Molmil](/molmil-images/mine/7xhu) | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with tricosanoic acid | Descriptor: | Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... | Authors: | Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. | Deposit date: | 2022-04-10 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (0.88 Å) | Cite: | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with tricosanoic acid To Be Published
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7XHT
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![BU of 7xht by Molmil](/molmil-images/mine/7xht) | Structure of the OgeuIscB-omega RNA-target DNA complex | Descriptor: | DNA (49-MER), DNA (5'-D(P*GP*AP*AP*GP*AP*AP*AP*AP*CP*CP*AP*T)-3'), LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | Kato, K, Okazaki, O, Isayama, Y, Ishikawa, J, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-04-10 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Structure of the IscB-omega RNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9. Nat Commun, 13, 2022
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7XHS
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![BU of 7xhs by Molmil](/molmil-images/mine/7xhs) | Crystal structure of CipA crystal produced by cell-free protein synthesis | Descriptor: | Cro/Cl family transcriptional regulator | Authors: | Abe, S, Tanaka, J, Kojima, M, Kanamaru, S, Yamashita, K, Hirata, K, Ueno, T. | Deposit date: | 2022-04-10 | Release date: | 2023-02-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Cell-free protein crystallization for nanocrystal structure determination. Sci Rep, 12, 2022
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7XHR
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![BU of 7xhr by Molmil](/molmil-images/mine/7xhr) | Crystal structure of Wild Type Cypovirus Polyhedra produced by cell-free protein synthesis | Descriptor: | ACETYL GROUP, CHLORIDE ION, Polyhedrin | Authors: | Abe, S, Tanaka, J, Kojima, M, Hirata, K, Yamashita, K, Ueno, T. | Deposit date: | 2022-04-10 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Cell-free protein crystallization for nanocrystal structure determination. Sci Rep, 12, 2022
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7XHM
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![BU of 7xhm by Molmil](/molmil-images/mine/7xhm) | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with behenic acid | Descriptor: | Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... | Authors: | Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. | Deposit date: | 2022-04-08 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (0.88 Å) | Cite: | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with behenic acid To Be Published
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7XH8
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![BU of 7xh8 by Molmil](/molmil-images/mine/7xh8) | The structure of ZCB11 Fab against SARS-CoV-2 Omicron Spike | Descriptor: | Spike glycoprotein, The heavy chain of ZCB11 antibody, The light chain of ZCB11 antibody | Authors: | Hang, L, Dang, S. | Deposit date: | 2022-04-07 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge. Nat Commun, 13, 2022
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7XH6
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![BU of 7xh6 by Molmil](/molmil-images/mine/7xh6) | Crystal structure of CBP bromodomain liganded with CCS1477 | Descriptor: | (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, DIMETHYL SULFOXIDE, ... | Authors: | Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-04-07 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
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7XH4
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![BU of 7xh4 by Molmil](/molmil-images/mine/7xh4) | Dihydrofolate Reductase-like Protein SacH in safracin biosynthesis complex with safracin A | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Safracin A, Uncharacterized protein sfcH | Authors: | Ma, X, Shao, N, Zhang, Y, Yang, D, Ma, M, Tang, G. | Deposit date: | 2022-04-07 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis. Acta Pharm Sin B, 13, 2023
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7XH2
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![BU of 7xh2 by Molmil](/molmil-images/mine/7xh2) | Dihydrofolate Reductase-like Protein SacH in safracin biosynthesis | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein sfcH | Authors: | Ma, X, Shao, N, Ma, M, Tang, G. | Deposit date: | 2022-04-07 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis. Acta Pharm Sin B, 13, 2023
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7XGW
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![BU of 7xgw by Molmil](/molmil-images/mine/7xgw) | |
7XGS
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![BU of 7xgs by Molmil](/molmil-images/mine/7xgs) | Short vegetative phase protein | Descriptor: | 1,2-ETHANEDIOL, MADS-box protein SVP | Authors: | Liao, Y.-T, Wang, H.-C, Ko, T.-P. | Deposit date: | 2022-04-06 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The PHYL1 effector of peanut witches broom (PnWB) phytoplasma alters the miR156/157-mediated squamosa promoter binding protein like regulation and gibberellic acid generation to promote anthocyanin biosynthesis To Be Published
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7XGQ
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7XGL
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![BU of 7xgl by Molmil](/molmil-images/mine/7xgl) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in Apo form | Descriptor: | CHLORIDE ION, GLYCEROL, Quinolinate Phosphoribosyl Transferase, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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