8SYO
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![BU of 8syo by Molmil](/molmil-images/mine/8syo) | Human Retriever VPS35L/VPS29/VPS26C Complex (Composite Map) | Descriptor: | VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 26C, Vacuolar protein sorting-associated protein 29 | Authors: | Chen, Z, Chen, B, Burstein, E, Han, Y. | Deposit date: | 2023-05-25 | Release date: | 2023-11-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural organization of the retriever-CCC endosomal recycling complex. Nat.Struct.Mol.Biol., 31, 2024
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4V3P
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![BU of 4v3p by Molmil](/molmil-images/mine/4v3p) | The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes | Descriptor: | 18S ribosomal RNA, 26S ribosomal RNA, 40S WHEAT GERM RIBOSOME protein 4, ... | Authors: | Myasnikov, A.G, Afonina, Z.A, Menetret, J.F, Shirokov, V.A, Spirin, A.S, Klaholz, B.P. | Deposit date: | 2014-10-20 | Release date: | 2015-04-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (34 Å) | Cite: | The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes. Nat Commun, 5, 2014
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4V1D
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![BU of 4v1d by Molmil](/molmil-images/mine/4v1d) | Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius. | Descriptor: | BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ... | Authors: | Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B. | Deposit date: | 2014-09-25 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin. J.Biol.Chem., 291, 2016
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4URK
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![BU of 4urk by Molmil](/molmil-images/mine/4urk) | PI3Kg in complex with AZD6482 | Descriptor: | 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | Authors: | Giordanetto, F, Barlaam, B, Berglund, S, Edman, K, Karlsson, O, Lindberg, J, Nylander, S, Inghardt, T. | Deposit date: | 2014-06-30 | Release date: | 2014-10-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Discovery of 9-(1-Phenoxyethyl)-2-Morpholino-4-Oxo-Pyrido[1, 2-A]Pyrimidine-7-Carboxamides as Oral Pi3Kbeta Inhibitors, Useful as Antiplatelet Agents. Bioorg.Med.Chem.Lett., 24, 2014
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4V65
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![BU of 4v65 by Molmil](/molmil-images/mine/4v65) | Structure of the E. coli ribosome in the Pre-accommodation state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Devkota, B, Caulfield, T.R, Tan, R.-Z, Harvey, S.C. | Deposit date: | 2008-08-03 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading To be Published
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4V8T
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![BU of 4v8t by Molmil](/molmil-images/mine/4v8t) | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | Descriptor: | 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... | Authors: | Greber, B.J, Boehringer, D, Montellese, C, Ban, N. | Deposit date: | 2012-08-07 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
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4W52
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![BU of 4w52 by Molmil](/molmil-images/mine/4w52) | T4 Lysozyme L99A with Benzene Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BENZENE, Endolysin | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5001 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4W54
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![BU of 4w54 by Molmil](/molmil-images/mine/4w54) | T4 Lysozyme L99A with Ethylbenzene Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, PHENYLETHANE | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7901 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4W57
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![BU of 4w57 by Molmil](/molmil-images/mine/4w57) | T4 Lysozyme L99A with n-Butylbenzene Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, N-BUTYLBENZENE | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6801 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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7C83
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![BU of 7c83 by Molmil](/molmil-images/mine/7c83) | Crystal structure of an integral membrane steroid 5-alpha-reductase PbSRD5A | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oxo-5-alpha-steroid 4-dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Ren, R.B, Han, Y.F, Xiao, Q.J, Deng, D. | Deposit date: | 2020-05-28 | Release date: | 2021-01-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. Nat Commun, 12, 2021
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7CVN
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![BU of 7cvn by Molmil](/molmil-images/mine/7cvn) | The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1 | Authors: | Wang, X, Zhou, J, Xu, B. | Deposit date: | 2020-08-26 | Release date: | 2020-09-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Design,synthesis,biological evaluation and binding mode analysis of 7-nitro-indole-N-acylarylsulfonamide-based fructose-1,6-bisphosphatase inhibitors Chinese journal of medicinal chemistry, 30, 2020
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4UQT
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![BU of 4uqt by Molmil](/molmil-images/mine/4uqt) | RRM-peptide structure in RES complex | Descriptor: | PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3 | Authors: | Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M. | Deposit date: | 2014-06-25 | Release date: | 2014-09-03 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex. J.Biol.Chem., 289, 2014
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7C2O
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![BU of 7c2o by Molmil](/molmil-images/mine/7c2o) | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, R-specific carbonyl reductase, ... | Authors: | Vinaykumar, K, KanalElamparithi, B, Chaudhury, D, Gunasekaran, K, Chadha, A. | Deposit date: | 2020-05-08 | Release date: | 2020-05-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT To Be Published
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4W51
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![BU of 4w51 by Molmil](/molmil-images/mine/4w51) | T4 Lysozyme L99A with No Ligand Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4UYI
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![BU of 4uyi by Molmil](/molmil-images/mine/4uyi) | Crystal structure of the BTB domain of human SLX4 (BTBD12) | Descriptor: | STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 | Authors: | Pinkas, D.M, Sanvitale, C.E, Strain-Damerell, C, Fairhead, M, Wang, D, Tallant, C, Cooper, C.D.O, Sorrell, F.J, Kopec, J, Chaikuad, A, Fitzpatrick, F, Pike, A.C.W, Hozjan, V, Ying, Z, Roos, A.K, Savitsky, P, Bradley, A, Nowak, R, Filippakopoulos, P, Krojer, T, Burgess-Brown, N.A, Marsden, B.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | Deposit date: | 2014-09-01 | Release date: | 2014-10-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure of the Btb Domain of Human Slx4 (Btbd12) To be Published
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4W53
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![BU of 4w53 by Molmil](/molmil-images/mine/4w53) | T4 Lysozyme L99A with Toluene Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, TOLUENE | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4W56
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![BU of 4w56 by Molmil](/molmil-images/mine/4w56) | T4 Lysozyme L99A with sec-Butylbenzene Bound | Descriptor: | (2R)-butan-2-ylbenzene, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4W59
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![BU of 4w59 by Molmil](/molmil-images/mine/4w59) | T4 Lysozyme L99A with n-Hexylbenzene Bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, hexylbenzene | Authors: | Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. | Deposit date: | 2014-08-16 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
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4UVK
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![BU of 4uvk by Molmil](/molmil-images/mine/4uvk) | |
8S6E
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![BU of 8s6e by Molmil](/molmil-images/mine/8s6e) | Monoclonal antibody MenW targeting serogroup W of Neisseria meningitidis | Descriptor: | MenW.01 Heavy chain, MenW.01 Light chain, SODIUM ION | Authors: | Pietri, G.P, Bertuzzi, S, Karnicar, K, Unione, L, Lisnic, B, Malic, S, Miklic, K, Novak, M, Calloni, I, Santini, L, Usenik, A, Rosaria Romano, M, Adamo, R, Jonjic, S, Turk, D, Jimenez-Barbero, J, Lenac Rovis, T. | Deposit date: | 2024-02-27 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Antigenic determinants driving serogroup-specific antibody response to Neisseria meningitidis C, W, and Y capsular polysaccharides: Insights for rational vaccine design. Carbohydr Polym, 341, 2024
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4WG7
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![BU of 4wg7 by Molmil](/molmil-images/mine/4wg7) | Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a nano focused beam. | Descriptor: | CHLORIDE ION, Lysozyme C | Authors: | Coquelle, N, Brewster, A.S, Kappe, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P. | Deposit date: | 2014-09-18 | Release date: | 2015-05-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams. Acta Crystallogr.,Sect.D, 71, 2015
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4WFZ
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4WFY
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![BU of 4wfy by Molmil](/molmil-images/mine/4wfy) | |
8TE6
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![BU of 8te6 by Molmil](/molmil-images/mine/8te6) | |
8TE5
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![BU of 8te5 by Molmil](/molmil-images/mine/8te5) | |