8XW0
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![BU of 8xw0 by Molmil](/molmil-images/mine/8xw0) | Cryo-EM structure of OSCA3.1-GDN state | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XVA
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![BU of 8xva by Molmil](/molmil-images/mine/8xva) | Human TOM complex with whole Tom20 | Descriptor: | Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | Authors: | Tian, X.Y, Su, J.Y, Sui, S.F. | Deposit date: | 2024-01-14 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (5.92 Å) | Cite: | Structure of the intact Tom20 receptor in the human translocase of the outer membrane complex. Pnas Nexus, 3, 2024
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8VM9
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![BU of 8vm9 by Molmil](/molmil-images/mine/8vm9) | |
8VMA
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![BU of 8vma by Molmil](/molmil-images/mine/8vma) | |
8VM8
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![BU of 8vm8 by Molmil](/molmil-images/mine/8vm8) | |
8VMB
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![BU of 8vmb by Molmil](/molmil-images/mine/8vmb) | |
8VLS
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![BU of 8vls by Molmil](/molmil-images/mine/8vls) | Structure of VCP in complex with an ATPase activator (D2 domains only, dodecameric form) | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | Deposit date: | 2024-01-12 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8ROZ
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![BU of 8roz by Molmil](/molmil-images/mine/8roz) | |
8ROP
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![BU of 8rop by Molmil](/molmil-images/mine/8rop) | Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | Deposit date: | 2024-01-12 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8VL9
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![BU of 8vl9 by Molmil](/molmil-images/mine/8vl9) | Crystal structure of EloBC-VHL-CDO1 complex bound to compound 8 molecular glue | Descriptor: | CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ... | Authors: | Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G. | Deposit date: | 2024-01-11 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A small molecule VHL molecular glue degrader for cysteine dioxygenase 1 To Be Published
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8RON
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![BU of 8ron by Molmil](/molmil-images/mine/8ron) | |
8ROM
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![BU of 8rom by Molmil](/molmil-images/mine/8rom) | |
8VLB
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![BU of 8vlb by Molmil](/molmil-images/mine/8vlb) | Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue | Descriptor: | CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ... | Authors: | Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G. | Deposit date: | 2024-01-11 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A small molecule VHL molecular glue degrader for cysteine dioxygenase 1 To Be Published
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8ROO
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![BU of 8roo by Molmil](/molmil-images/mine/8roo) | Crystal structure of HLA B*18:01 in complex with YERMCNIL, an 8-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Influenza A derived peptide/Nucleoprotein, ... | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | Deposit date: | 2024-01-11 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8RO1
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![BU of 8ro1 by Molmil](/molmil-images/mine/8ro1) | Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'') | Descriptor: | CWF19-like protein 1 homolog, CWF19-like protein 2 homolog, Cell division cycle 5-like protein, ... | Authors: | Vorlaender, M.K, Rothe, P, Plaschka, C. | Deposit date: | 2024-01-11 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism for the initiation of spliceosome disassembly. Nature, 632, 2024
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8RO0
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![BU of 8ro0 by Molmil](/molmil-images/mine/8ro0) | Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS') | Descriptor: | Cell division cycle 5-like protein, Coiled-coil domain-containing protein 12, GCF C-terminal domain-containing protein, ... | Authors: | Vorlaender, M.K, Rothe, P, Plaschka, C. | Deposit date: | 2024-01-11 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism for the initiation of spliceosome disassembly. Nature, 632, 2024
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8XT1
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![BU of 8xt1 by Molmil](/molmil-images/mine/8xt1) | Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSX
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![BU of 8xsx by Molmil](/molmil-images/mine/8xsx) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT3
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![BU of 8xt3 by Molmil](/molmil-images/mine/8xt3) | Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSZ
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![BU of 8xsz by Molmil](/molmil-images/mine/8xsz) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSY
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![BU of 8xsy by Molmil](/molmil-images/mine/8xsy) | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT0
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![BU of 8xt0 by Molmil](/molmil-images/mine/8xt0) | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT2
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![BU of 8xt2 by Molmil](/molmil-images/mine/8xt2) | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8RNH
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![BU of 8rnh by Molmil](/molmil-images/mine/8rnh) | Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Murdolo, L.D, Maddumaage, J, Gras, S. | Deposit date: | 2024-01-10 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8RNG
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![BU of 8rng by Molmil](/molmil-images/mine/8rng) | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGNESIUM ION, ... | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | Deposit date: | 2024-01-10 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A To Be Published
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