8ROZ
Cryo-EM structure of CDK2-cyclin A in complex with CDC25A
Summary for 8ROZ
Entry DOI | 10.2210/pdb8roz/pdb |
EMDB information | 19408 |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, M-phase inducer phosphatase 1 (3 entities in total) |
Functional Keywords | cell-cycle, cdk, phosphatase, cancer, cell cycle |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 86789.37 |
Authors | Rowland, R.J.,Noble, M.E.M.,Endicott, J.A. (deposition date: 2024-01-12, release date: 2024-05-29, Last modification date: 2024-08-28) |
Primary citation | Rowland, R.J.,Korolchuk, S.,Salamina, M.,Tatum, N.J.,Ault, J.R.,Hart, S.,Turkenburg, J.P.,Blaza, J.N.,Noble, M.E.M.,Endicott, J.A. Cryo-EM structure of the CDK2-cyclin A-CDC25A complex. Nat Commun, 15:6807-6807, 2024 Cited by PubMed: 39122719DOI: 10.1038/s41467-024-51135-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
Download full validation report