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7R6Q
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BU of 7r6q by Molmil
State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-23
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7PCV
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BU of 7pcv by Molmil
Crystal structure of RBM5 RRM1-zinc finger
Descriptor: RNA-binding protein 5, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-04
Release date:2022-08-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
2VON
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BU of 2von by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAAUUU
Descriptor: 5'-R(*AP*UP*AP*AP*UP*UP*UP)-3', LUPUS LA PROTEIN
Authors:Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
Deposit date:2008-02-19
Release date:2008-05-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
8I9T
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BU of 8i9t by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9P
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BU of 8i9p by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16
Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9Z
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BU of 8i9z by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9X
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BU of 8i9x by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8IA0
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BU of 8ia0 by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9R
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BU of 8i9r by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP
Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9V
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BU of 8i9v by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9W
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BU of 8i9w by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9Y
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BU of 8i9y by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2
Descriptor: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
Authors:Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
Deposit date:2023-02-07
Release date:2023-05-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8IDF
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BU of 8idf by Molmil
Crystal structure of human TUT1 complexed with U6 snRNA
Descriptor: RNA (53-MER), Speckle targeted PIP5K1A-regulated poly(A) polymerase, ZINC ION
Authors:Yamashita, S, Tomita, K.
Deposit date:2023-02-13
Release date:2023-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanism of U6 snRNA oligouridylation by human TUT1.
Nat Commun, 14, 2023
8IPX
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BU of 8ipx by Molmil
human nuclear pre-60S ribosomal particle - State C'
Descriptor: 28S rRNA, 5.8S rRNA, 5S RNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-15
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8INE
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BU of 8ine by Molmil
human nuclear pre-60S ribosomal particle - State G'
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8IPY
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BU of 8ipy by Molmil
human nuclear pre-60S ribosomal particle - State D'
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-15
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8INF
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BU of 8inf by Molmil
human nuclear pre-60S ribosomal particle - State F'
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
7ABH
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BU of 7abh by Molmil
Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)
Descriptor: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7B0Y
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BU of 7b0y by Molmil
Structure of a transcribing RNA polymerase II-U1 snRNP complex
Descriptor: 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ...
Authors:Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P.
Deposit date:2020-11-23
Release date:2021-01-13
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a transcribing RNA polymerase II-U1 snRNP complex.
Science, 371, 2021
7A5P
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BU of 7a5p by Molmil
Human C Complex Spliceosome - Medium-resolution PERIPHERY
Descriptor: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-21
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
6ZON
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BU of 6zon by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-07
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
7C06
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BU of 7c06 by Molmil
Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Descriptor: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
Authors:Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
Deposit date:2020-04-30
Release date:2020-09-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
7C08
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BU of 7c08 by Molmil
Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Descriptor: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
Authors:Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
Deposit date:2020-04-30
Release date:2020-09-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020

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