PDB: 494 resultsInfo pagesStatus searchChemie searchBIRD

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2P8Q	Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain Descriptor: Importin beta-1 subunit, Snurportin-1 Authors: Mitrousis, G, Cingolani, G. Deposit date: 2007-03-22 Release date: 2008-01-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
4ZDU	Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein Descriptor: Importin subunit alpha-1, Peptide from Nucleoprotein Authors: Nakada, R, Hirano, H, Matsuura, Y. Deposit date: 2015-04-19 Release date: 2015-10-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein Sci Rep, 5, 2015
2Q5D	Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form Descriptor: Importin beta-1 subunit, Snurportin-1 Authors: Mitrousis, G, Cingolani, G. Deposit date: 2007-05-31 Release date: 2008-01-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
6IUA	Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (S1678D) Descriptor: Importin subunit alpha-1, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2018-11-27 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha. Biochem. Biophys. Res. Commun., 510, 2019
6IU7	Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (wild-type) Descriptor: Importin subunit alpha-1, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2018-11-27 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha. Biochem. Biophys. Res. Commun., 510, 2019
4XRK	Crystal Structure of Importin Beta in a Polyethylene Glycol Condition Descriptor: Importin Beta Authors: Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A. Deposit date: 2015-01-21 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Impact of the crystallization condition on importin-beta conformation. Acta Crystallogr D Struct Biol, 72, 2016
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS Descriptor: Importin subunit alpha, Large T antigen Authors: Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2014-12-11 Release date: 2015-07-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7553 Å) Cite: Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
4OIH	Importin Alpha in Complex with the Bipartite NLS of Prp20 Descriptor: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1 Authors: Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K. Deposit date: 2014-01-19 Release date: 2014-02-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20 Plos One, 8, 2013
8Q8K	KI Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-18 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
6BWB	Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 Descriptor: Importin subunit alpha-3, Protein W Authors: Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-14 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
6BWA	Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2 Descriptor: Importin subunit alpha-3, Protein W Authors: Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-14 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
1PJN	Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex Descriptor: Histone-binding protein N1/N2, Importin alpha-2 subunit Authors: Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. Deposit date: 2003-06-03 Release date: 2003-08-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
6BW9	Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1 Descriptor: Importin subunit alpha-3, Protein W Authors: Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-14 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
6BW1	Hendra virus W protein C-terminus in complex with Importin alpha 1 Descriptor: Importin subunit alpha-1, Protein W Authors: Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-14 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
6BW0	Nipah virus W protein C-terminus in complex with Importin alpha 1 Descriptor: Importin subunit alpha-1, Protein W Authors: Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-14 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
5K9S	Importin-alpha in complex with HNF1-beta peptide Descriptor: HNF1 beta A splice variant 2, Importin subunit alpha-1 Authors: Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. Deposit date: 2016-06-01 Release date: 2016-11-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Importin-alpha in complex with HNF1-beta peptide To Be Published
1Q1S	Mouse Importin alpha- phosphorylated SV40 CN peptide complex Descriptor: Importin alpha-2 subunit, Large T antigen Authors: Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. Deposit date: 2003-07-22 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
1Q1T	Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex Descriptor: Importin alpha-2 subunit, Large T antigen Authors: Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. Deposit date: 2003-07-22 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
3UL1	Mouse importin alpha: nucleoplasmin cNLS peptide complex Descriptor: Importin subunit alpha-2, Nucleoplasmin Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3FEY	Crystal structure of the CBC-importin alpha complex. Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 Authors: Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. Deposit date: 2008-12-01 Release date: 2009-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
3FEX	Crystal structure of the CBC-importin alpha complex. Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 Authors: Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. Deposit date: 2008-12-01 Release date: 2009-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.549 Å) Cite: The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
6BVV	Nipah virus W protein C-terminus in complex with Importin alpha 3 Descriptor: Importin subunit alpha-3, Protein W Authors: Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. Deposit date: 2017-12-13 Release date: 2018-07-04 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
3UKZ	Mouse importin alpha: mouse CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKY	Mouse importin alpha: yeast CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3RZX	Mouse importin alpha-Ku70 NLS peptide complex Descriptor: Importin subunit alpha-2, Ku70 NLS peptide Authors: Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2011-05-12 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011

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