2FB2
 
 | | Structure of the MoaA Arg17/266/268/Ala triple mutant | | 分子名称: | IRON/SULFUR CLUSTER, Molybdenum cofactor biosynthesis protein A, S-ADENOSYLMETHIONINE, ... | | 著者 | Haenzelmann, P, Schindelin, H. | | 登録日 | 2005-12-08 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism
Proc.Natl.Acad.Sci.USA, 103, 2006
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1OLT
 | | Coproporphyrinogen III oxidase (HemN) from Escherichia coli is a Radical SAM enzyme. | | 分子名称: | IRON/SULFUR CLUSTER, OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE, S-ADENOSYLMETHIONINE | | 著者 | Layer, G, Moser, J, Heinz, D.W, Jahn, D, Schubert, W.-D. | | 登録日 | 2003-08-13 | | 公開日 | 2003-12-04 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes
Embo J., 22, 2003
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4RTB
 | | X-ray structure of the FeFe-hydrogenase maturase HydG from Carboxydothermus hydrogenoformans | | 分子名称: | CHLORIDE ION, HydG protein, IRON/SULFUR CLUSTER, ... | | 著者 | Nicolet, Y, Pagnier, A, Zeppieri, L, Martin, L, Amara, P, Fontecilla-Camps, J.C. | | 登録日 | 2014-11-14 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Crystal Structure of HydG from Carboxydothermus hydrogenoformans: A Trifunctional [FeFe]-Hydrogenase Maturase.
Chembiochem, 16, 2015
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6Q2P
 | | Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. | | 登録日 | 2019-08-08 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.452 Å) | | 主引用文献 | Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
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6Q2Q
 | | Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | | 著者 | Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. | | 登録日 | 2019-08-08 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
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5L7J
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5L7L
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7PD2
 | | Crystal structure of the substrate-free radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | 分子名称: | 5'-DEOXYADENOSINE, GLYCEROL, IRON/SULFUR CLUSTER, ... | | 著者 | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
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7PD1
 | | Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | 分子名称: | 5'-DEOXYADENOSINE, BROMIDE ION, GLYCEROL, ... | | 著者 | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
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6B4C
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5HR6
 | | X-ray crystal structure of C118A RlmN with cross-linked tRNA purified from Escherichia coli | | 分子名称: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Schwalm, E.L, Grove, T.L, Booker, S.J, Boal, A.K. | | 登録日 | 2016-01-22 | | 公開日 | 2016-04-13 | | 最終更新日 | 2016-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Science, 352, 2016
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6C8V
 | | X-ray structure of PqqE from Methylobacterium extorquens | | 分子名称: | Coenzyme PQQ synthesis protein E, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER | | 著者 | Gizzi, A.S, Grove, T.L, Bonanno, J.B, Almo, S.C. | | 登録日 | 2018-01-25 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.
Biochemistry, 57, 2018
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5HR7
 | | X-ray crystal structure of C118A RlmN from Escherichia coli with cross-linked in vitro transcribed tRNA | | 分子名称: | 5'-DEOXYADENOSINE, Dual-specificity RNA methyltransferase RlmN, IRON/SULFUR CLUSTER, ... | | 著者 | Schwalm, E.L, Grove, T.L, Booker, S.J, Boal, A.K. | | 登録日 | 2016-01-22 | | 公開日 | 2016-04-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Science, 352, 2016
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2A5H
 | | 2.1 Angstrom X-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale SB4, with Michaelis analog (L-alpha-lysine external aldimine form of pyridoxal-5'-phosphate). | | 分子名称: | IRON/SULFUR CLUSTER, L-lysine 2,3-aminomutase, LYSINE, ... | | 著者 | Lepore, B.W, Ruzicka, F.J, Frey, P.A, Ringe, D. | | 登録日 | 2005-06-30 | | 公開日 | 2005-10-04 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The X-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2FB3
 | | Structure of MoaA in complex with 5'-GTP | | 分子名称: | 5'-DEOXYADENOSINE, GUANOSINE-5'-TRIPHOSPHATE, IRON/SULFUR CLUSTER, ... | | 著者 | Haenzelmann, P, Schindelin, H. | | 登録日 | 2005-12-08 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.349 Å) | | 主引用文献 | Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism
Proc.Natl.Acad.Sci.USA, 103, 2006
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8VPO
 | | X-Ray Crystal Structure of TigE from Paramaledivibacter caminithermalis | | 分子名称: | GLYCEROL, IRON/SULFUR CLUSTER, Radical SAM core domain-containing protein | | 著者 | Grove, T.L, Lachowicz, J.C, Zizola, C. | | 登録日 | 2024-01-16 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases.
Acs Chem.Biol., 19, 2024
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8VCW
 | | X-Ray Crystal Structure of the biotin synthase from B. obeum | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Biotin synthase, ... | | 著者 | Lachowicz, J.C, Grove, T.L. | | 登録日 | 2023-12-14 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion.
J.Am.Chem.Soc., 146, 2024
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8VDW
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1R30
 | | The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Biotin synthase, ... | | 著者 | Berkovitch, F, Nicolet, Y, Wan, J.T, Jarrett, J.T, Drennan, C.L. | | 登録日 | 2003-09-30 | | 公開日 | 2004-01-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.
Science, 303, 2004
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3RFA
 | | X-ray structure of RlmN from Escherichia coli in complex with S-adenosylmethionine | | 分子名称: | IRON/SULFUR CLUSTER, Ribosomal RNA large subunit methyltransferase N, S-ADENOSYLMETHIONINE | | 著者 | Boal, A.K, Grove, T.L, McLaughlin, M.I, Yennawar, N, Booker, S.J, Rosenzweig, A.C. | | 登録日 | 2011-04-05 | | 公開日 | 2011-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
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3RF9
 | | X-ray structure of RlmN from Escherichia coli | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, IRON/SULFUR CLUSTER, Ribosomal RNA large subunit methyltransferase N | | 著者 | Boal, A.K, Grove, T.L, McLaughlin, M.I, Yennawar, N, Booker, S.J, Rosenzweig, A.C. | | 登録日 | 2011-04-05 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
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8FO0
 | | The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to a partially cleaved SAM molecule | | 分子名称: | IRON/SULFUR CLUSTER, POTASSIUM ION, Pyruvate formate-lyase 1-activating enzyme, ... | | 著者 | Moody, J.D, Saxton, A.J, Galambas, A, Lawrence, C.M, Broderick, J.B. | | 登録日 | 2022-12-29 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.
J.Biol.Chem., 299, 2023
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8FOL
 | | The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to SAM, alternate crystal form | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, POTASSIUM ION, ... | | 著者 | Moody, J.D, Saxton, A.J, Galambas, A, Lawrence, C.M, Broderick, J.B. | | 登録日 | 2022-12-31 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.
J.Biol.Chem., 299, 2023
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8FSI
 | | The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to SAM | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, POTASSIUM ION, ... | | 著者 | Moody, J.D, Galambas, A, Lawrence, C.M, Broderick, J.B. | | 登録日 | 2023-01-10 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.
J.Biol.Chem., 299, 2023
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1TV7
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