8FSI
The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to SAM
Summary for 8FSI
| Entry DOI | 10.2210/pdb8fsi/pdb |
| Related | 8FO0 8FOL |
| Descriptor | Pyruvate formate-lyase 1-activating enzyme, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (6 entities in total) |
| Functional Keywords | radical sam, activase, pfl, oxidoreductase |
| Biological source | Escherichia coli K-12 |
| Total number of polymer chains | 1 |
| Total formula weight | 29101.00 |
| Authors | Moody, J.D.,Galambas, A.,Lawrence, C.M.,Broderick, J.B. (deposition date: 2023-01-10, release date: 2023-05-24, Last modification date: 2023-06-21) |
| Primary citation | Moody, J.D.,Hill, S.,Lundahl, M.N.,Saxton, A.J.,Galambas, A.,Broderick, W.E.,Lawrence, C.M.,Broderick, J.B. Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage. J.Biol.Chem., 299:104791-104791, 2023 Cited by PubMed: 37156396DOI: 10.1016/j.jbc.2023.104791 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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