PDB: 660 resultsInfo pagesStatus searchChemie searchBIRD

---

8YR7	Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif Descriptor: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19 Authors: Omble, A, Mahajan, S, Kulkarni, K.A. Deposit date: 2024-03-20 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF. Commun Biol, 7, 2024
6EEY	Crystal structure of human Scribble PDZ4 R1110G Mutant Descriptor: Protein scribble homolog Authors: Janezic, E.M, Hsu, P, Hague, C. Deposit date: 2018-08-15 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.145 Å) Cite: Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands. Sci Rep, 9, 2019
7JO7	Crystal Structure of Human Scribble PDZ2 Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog Authors: How, J.Y, Kvansakul, M. Deposit date: 2020-08-06 Release date: 2021-03-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Structural basis of the human Scribble-Vangl2 association in health and disease. Biochem.J., 478, 2021
7JZQ	CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB Descriptor: 4-[(piperidin-1-yl)methyl]benzoic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALPMB peptide core Authors: Gill, N.P, Madden, D.R. Deposit date: 2020-09-02 Release date: 2021-10-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.35 Å) Cite: CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB To Be Published
7JZR	CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAEB Descriptor: 4-(2-aminoethyl)benzoic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALAEB peptide core Authors: Gill, N.P, Madden, D.R. Deposit date: 2020-09-02 Release date: 2021-10-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.54 Å) Cite: CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAEB To Be Published
7JZO	CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALTPP Descriptor: 3-(thiophen-2-yl)propanoic acid, GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, ... Authors: Gill, N.P, Madden, D.R. Deposit date: 2020-09-02 Release date: 2021-10-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.61 Å) Cite: CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALTPP To Be Published
7JZP	CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALBF Descriptor: 1-benzofuran-2-carboxylic acid, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALBF peptide core Authors: Gill, N.P, Madden, D.R. Deposit date: 2020-09-02 Release date: 2022-02-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALBF To Be Published
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. Descriptor: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 Authors: Loew, C, Flayhan, A, Pieprzyk, J. Deposit date: 2017-11-15 Release date: 2018-09-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.503321 Å) Cite: Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
6ESP	Proteome-wide analysis of phospho-regulated PDZ domain interactions Descriptor: Protein scribble homolog Authors: Chi, N.C. Deposit date: 2017-10-24 Release date: 2018-09-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Proteome-wide analysis of phospho-regulated PDZ domain interactions. Mol. Syst. Biol., 14, 2018
1D5G	SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE Descriptor: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV Authors: Kozlov, G, Gehring, K, Ekiel, I. Deposit date: 1999-10-07 Release date: 2002-07-24 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions J.Mol.Biol., 320, 2002
5WOU	Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder Descriptor: 1,2-ETHANEDIOL, GUK-holder, isoform A, ... Authors: Caria, S, Kvansakul, M. Deposit date: 2017-08-03 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large. J. Biol. Chem., 293, 2018
6GBD	Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain Descriptor: PDZ3 Authors: Kock, G, Stoll, R. Deposit date: 2018-04-13 Release date: 2018-12-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13. J. Mol. Biol., 430, 2018
5VWC	Crystal structure of human Scribble PDZ1 domain Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog Authors: Lim, K.Y.B, Kvansakul, M. Deposit date: 2017-05-21 Release date: 2017-11-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.911 Å) Cite: Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5W72	Impact of IR active probes on PDZ3 and its ligand binding studied by NMR and X-ray crystallography Descriptor: Disks large homolog 4 Authors: Lehner, F, Kudlinzki, D, Schwalbe, H, Silvers, R. Deposit date: 2017-06-19 Release date: 2017-12-13 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
6GBE	Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain-PRK2 Peptide Complex Descriptor: Serine/threonine-protein kinase N2, Tyrosine-protein phosphatase non-receptor type 13 Authors: Kock, G, Stoll, R. Deposit date: 2018-04-13 Release date: 2018-12-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13. J. Mol. Biol., 430, 2018
1GM1	Second PDZ Domain (PDZ2) of PTP-BL Descriptor: PROTEIN TYROSINE PHOSPHATASE Authors: Walma, T, Tessari, M, Aelen, J, Schepens, J, Hendriks, W, Vuister, G.W. Deposit date: 2001-09-06 Release date: 2002-03-08 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL. J. Mol. Biol., 316, 2002
5VWI	Crystal structure of human Scribble PDZ1:Beta-PIX complex Descriptor: Protein scribble homolog, beta-PIX Authors: Lim, K.Y.B, Kvansakul, M. Deposit date: 2017-05-22 Release date: 2017-11-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
7LUL	Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2021-02-22 Release date: 2021-07-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
1G9O	FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR Descriptor: NHE-RF Authors: Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. Deposit date: 2000-11-26 Release date: 2001-05-23 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
1GQ4	STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 Authors: Karthikeyan, S, Leung, T, Ladias, J.A.A. Deposit date: 2001-11-19 Release date: 2002-05-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors J.Biol.Chem., 277, 2002
1GQ5	Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 Authors: Karthikeyan, S, Leung, T, Ladias, J.A.A. Deposit date: 2001-11-20 Release date: 2002-11-14 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors J.Biol.Chem., 277, 2002
1I16	STRUCTURE OF INTERLEUKIN 16: IMPLICATIONS FOR FUNCTION, NMR, 20 STRUCTURES Descriptor: INTERLEUKIN 16 Authors: Muehlhahn, P, Zweckstetter, M, Georgescu, J, Ciosto, C, Renner, C, Lanzendoerfer, M, Lang, K, Ambrosius, D, Baier, M, Kurth, R, Holak, T.A. Deposit date: 1998-05-20 Release date: 1999-05-25 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site. Nat.Struct.Biol., 5, 1998
5ZDS	Crystal structure of the second PDZ domain of Frmpd2 Descriptor: FERM and PDZ domain-containing 2 Authors: Lu, X, Wang, X.F. Deposit date: 2018-02-24 Release date: 2019-02-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem.Biophys.Res.Commun., 516, 2019
5ZYS	Structure of Nephrin/MAGI1 complex Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin Authors: Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. Deposit date: 2018-05-28 Release date: 2019-01-23 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling. J. Am. Soc. Nephrol., 29, 2018
6ZBQ	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 5-fluoranyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021

<12345678910111213141516>