8CRO
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![BU of 8cro by Molmil](/molmil-images/mine/8cro) | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex | Descriptor: | DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... | Authors: | Tarau, D.M, Grunberger, F, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | Deposit date: | 2023-03-08 | Release date: | 2024-04-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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7NKY
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![BU of 7nky by Molmil](/molmil-images/mine/7nky) | RNA Polymerase II-Spt4/5-nucleosome-FACT structure | Descriptor: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | Authors: | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | Deposit date: | 2021-02-19 | Release date: | 2021-07-07 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
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2R93
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![BU of 2r93 by Molmil](/molmil-images/mine/2r93) | Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Lehmann, E, Brueckner, F, Cramer, P. | Deposit date: | 2007-09-12 | Release date: | 2007-11-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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5IP7
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![BU of 5ip7 by Molmil](/molmil-images/mine/5ip7) | Structure of RNA Polymerase II-Tfg1 peptide complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-03-09 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Transcription initiation complex structures elucidate DNA opening. Nature, 533, 2016
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3QT1
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![BU of 3qt1 by Molmil](/molmil-images/mine/3qt1) | RNA polymerase II variant containing A Chimeric RPB9-C11 subunit | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. | Deposit date: | 2011-02-22 | Release date: | 2011-03-23 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Evolution of two modes of intrinsic RNA polymerase transcript cleavage. J.Biol.Chem., 286, 2011
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3PO3
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![BU of 3po3 by Molmil](/molmil-images/mine/3po3) | Arrested RNA Polymerase II reactivation intermediate | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DNA non-template strand, ... | Authors: | Cheung, A.C.M, Cramer, P. | Deposit date: | 2010-11-21 | Release date: | 2011-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature, 471, 2011
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3PO2
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![BU of 3po2 by Molmil](/molmil-images/mine/3po2) | Arrested RNA Polymerase II elongation complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Cheung, A.C.M, Cramer, P. | Deposit date: | 2010-11-21 | Release date: | 2011-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature, 471, 2011
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1E3H
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![BU of 1e3h by Molmil](/molmil-images/mine/1e3h) | SeMet derivative of Streptomyces antibioticus PNPase/GPSI enzyme | Descriptor: | GUANOSINE PENTAPHOSPHATE SYNTHETASE, SULFATE ION | Authors: | Symmons, M.F, Jones, G.H, Luisi, B.F. | Deposit date: | 2000-06-15 | Release date: | 2000-11-05 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Duplicated Fold is the Structural Basis for Polynucleotide Phosphorylase Catalytic Activity, Processivity, and Regulation Structure, 8, 2000
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1E3P
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![BU of 1e3p by Molmil](/molmil-images/mine/1e3p) | tungstate derivative of Streptomyces antibioticus PNPase/GPSI enzyme | Descriptor: | Polyribonucleotide nucleotidyltransferase, SULFATE ION, TUNGSTATE(VI)ION | Authors: | Symmons, M.F, Jones, G.H, Luisi, B.F. | Deposit date: | 2000-06-20 | Release date: | 2000-11-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Duplicated Fold is the Structural Basis for Polynucleotide Phosphorylase Catalytic Activity, Processivity, and Regulation Structure, 8, 2000
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3V11
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![BU of 3v11 by Molmil](/molmil-images/mine/3v11) | |
4V1N
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![BU of 4v1n by Molmil](/molmil-images/mine/4v1n) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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4V1O
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![BU of 4v1o by Molmil](/molmil-images/mine/4v1o) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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4V8S
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![BU of 4v8s by Molmil](/molmil-images/mine/4v8s) | Archaeal RNAP-DNA binary complex at 4.32Ang | Descriptor: | 5'-D(*AP*TP*AP*GP*AP*GP*TP*AP*TP*AP*AP*GP*AP*TP *AP*G)-3', 5'-D(*TP*CP*TP*TP*AP*TP*AP*CP*TP*CP*TP*AP*TP*CP)-3', DNA-DIRECTED RNA POLYMERASE, ... | Authors: | Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2012-07-12 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.323 Å) | Cite: | Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA. Nucleic Acids Res., 40, 2012
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3FKI
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![BU of 3fki by Molmil](/molmil-images/mine/3fki) | 12-Subunit RNA Polymerase II Refined with Zn-SAD data | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Meyer, P.A, Ye, P, Suh, M.H, Zhang, M, Fu, J. | Deposit date: | 2008-12-16 | Release date: | 2009-03-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.88 Å) | Cite: | Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data J.Biol.Chem., 284, 2009
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3H3V
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![BU of 3h3v by Molmil](/molmil-images/mine/3h3v) | Yeast RNAP II containing poly(A)-signal sequence in the active site | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... | Authors: | Dengl, S, Cramer, P. | Deposit date: | 2009-04-17 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
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3H0G
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![BU of 3h0g by Molmil](/molmil-images/mine/3h0g) | RNA Polymerase II from Schizosaccharomyces pombe | Descriptor: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2009-04-09 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc.Natl.Acad.Sci.USA, 106, 2009
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5OT2
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![BU of 5ot2 by Molmil](/molmil-images/mine/5ot2) | RNA polymerase II elongation complex in the presence of 3d-Napht-A | Descriptor: | 2-ethyl-7-methoxy-naphthalene, DNA non-template strand, DNA template strand, ... | Authors: | Malvezzi, S, Farnung, L, Aloisi, C, Angelov, T, Cramer, P, Sturla, S.J. | Deposit date: | 2017-08-19 | Release date: | 2017-11-01 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Mechanism of RNA polymerase II stalling by DNA alkylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6LQU
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![BU of 6lqu by Molmil](/molmil-images/mine/6lqu) | |
4Q7J
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![BU of 4q7j by Molmil](/molmil-images/mine/4q7j) | Complex structure of viral RNA polymerase | Descriptor: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ... | Authors: | Takeshita, D. | Deposit date: | 2014-04-25 | Release date: | 2014-08-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1. Nucleic Acids Res., 42, 2014
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6LQS
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6LQR
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![BU of 6lqr by Molmil](/molmil-images/mine/6lqr) | |
5U5Q
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![BU of 5u5q by Molmil](/molmil-images/mine/5u5q) | 12 Subunit RNA Polymerase II at Room Temperature collected using SFX | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A. | Deposit date: | 2016-12-07 | Release date: | 2017-03-29 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Double-flow focused liquid injector for efficient serial femtosecond crystallography. Sci Rep, 7, 2017
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6LQT
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![BU of 6lqt by Molmil](/molmil-images/mine/6lqt) | |
4BY7
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![BU of 4by7 by Molmil](/molmil-images/mine/4by7) | elongating RNA Polymerase II-Bye1 TLD complex | Descriptor: | , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | Deposit date: | 2013-07-18 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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6LQQ
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![BU of 6lqq by Molmil](/molmil-images/mine/6lqq) | |