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4ZRJ
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BU of 4zrj by Molmil
Structure of Merlin-FERM and CTD
Descriptor: GLYCEROL, Merlin
Authors:Lin, Z, Li, F, Long, J, Shen, Y.
Deposit date:2015-05-12
Release date:2015-06-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
4YL8
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BU of 4yl8 by Molmil
Crystal structure of the Crumbs/Moesin complex
Descriptor: GLYCEROL, IODIDE ION, Moesin, ...
Authors:Wei, Z, Li, Y, Zhang, M.
Deposit date:2015-03-05
Release date:2015-04-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin
J.Biol.Chem., 290, 2015
2D10
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BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
1NI2
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BU of 1ni2 by Molmil
Structure of the active FERM domain of Ezrin
Descriptor: Ezrin
Authors:Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
6D2Q
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BU of 6d2q by Molmil
Crystal structure of the FERM domain of zebrafish FARP1
Descriptor: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Authors:Kuo, Y.C, Zhang, X.
Deposit date:2018-04-13
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
6D2K
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BU of 6d2k by Molmil
Crystal structure of the FERM domain of mouse FARP2
Descriptor: FERM, ARHGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2018-04-13
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
1EF1
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BU of 1ef1 by Molmil
CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor: MOESIN, SULFATE ION
Authors:Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
1E5W
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BU of 1e5w by Molmil
Structure of isolated FERM domain and first long helix of moesin
Descriptor: MOESIN
Authors:Edwards, S.D, Keep, N.H.
Deposit date:2000-08-03
Release date:2001-06-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
6CB0
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BU of 6cb0 by Molmil
Crystal Structure of the FAK FERM domain
Descriptor: Focal adhesion kinase 1
Authors:Dementiev, A, Marlowe, T.
Deposit date:2018-02-01
Release date:2019-02-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site.
BMC Mol Cell Biol, 20, 2019
6D21
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BU of 6d21 by Molmil
Crystal structure of the FERM domain of zebrafish FARP2
Descriptor: FERM, RhoGEF and pleckstrin domain protein 2
Authors:Kuo, Y.C, Zhang, X.
Deposit date:2018-04-12
Release date:2018-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
2EMS
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BU of 2ems by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43
Descriptor: Leukosialin, Radixin
Authors:Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
6CDS
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BU of 6cds by Molmil
Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ...
Authors:Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T.
Deposit date:2018-02-09
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun, 9, 2018
2EMT
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BU of 2emt by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1
Descriptor: P-selectin glycoprotein ligand 1, Radixin
Authors:Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
1MK7
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BU of 1mk7 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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BU of 1miz by Molmil
Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1GG3
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BU of 1gg3 by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor: ERYTHROID MEMBRANE PROTEIN 4.1R
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1GC6
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BU of 1gc6 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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BU of 1gc7 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor: RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1MK9
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BU of 1mk9 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
2D2Q
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BU of 2d2q by Molmil
Crystal structure of the dimerized radixin FERM domain
Descriptor: Radixin
Authors:Kitano, K, Yusa, F, Hakoshima, T.
Deposit date:2005-09-15
Release date:2006-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2YVC
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BU of 2yvc by Molmil
Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
Descriptor: Neprilysin, Radixin
Authors:Terawaki, S, Kitano, K, Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
8TEC
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BU of 8tec by Molmil
Crystal structure of Kindlin2 in complex with acylated beta1 integrin peptide
Descriptor: Fermitin family homolog 2, Integrin beta-1
Authors:Zhang, P.F, Wu, J.H.
Deposit date:2023-07-06
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
Iscience, 27, 2024
8T0D
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BU of 8t0d by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation
Descriptor: Integrin beta-2,Talin-1
Authors:Wu, J, Gao, T.
Deposit date:2023-05-31
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024

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