7OM3
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![BU of 7om3 by Molmil](/molmil-images/mine/7om3) | Crystal structure of KOD DNA Polymerase in a binary complex with Hypoxanthine containing template | Descriptor: | 1,2-ETHANEDIOL, 21nt Template, BROMIDE ION, ... | Authors: | Betz, K, Kropp, H.M, Diederichs, K, Marx, A. | Deposit date: | 2021-05-21 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
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7OPL
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![BU of 7opl by Molmil](/molmil-images/mine/7opl) | |
1WN7
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![BU of 1wn7 by Molmil](/molmil-images/mine/1wn7) | Crystal structure of archaeal family B DNA polymerase mutant | Descriptor: | Family B DNA Polymerase, GLYCEROL, NICKEL (II) ION | Authors: | Kuroita, T, Matsumura, H, Yokota, N, Hashimoto, H, Imanaka, T, Inoue, T, Kai, Y. | Deposit date: | 2004-07-28 | Release date: | 2005-08-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Mechanism for Coordination of Proofreading and Polymerase Activities in Archaeal DNA Polymerases J.Mol.Biol., 351, 2005
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1WNS
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![BU of 1wns by Molmil](/molmil-images/mine/1wns) | Crystal structure of family B DNA polymerase from hyperthermophilic archaeon pyrococcus kodakaraensis KOD1 | Descriptor: | DNA POLYMERASE | Authors: | Hashimoto, H, Inoue, T, Kai, Y, Fujiwara, S, Takagi, M, Nishioka, M, Imanaka, T. | Deposit date: | 2004-08-09 | Release date: | 2004-08-17 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of DNA Polymerase from Hyperthermophilic Archaeon Pyrococcus Kodakaraensis Kod1 J.Mol.Biol., 306, 2001
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6S1N
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![BU of 6s1n by Molmil](/molmil-images/mine/6s1n) | Human polymerase delta holoenzyme Conformer 2 | Descriptor: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | Authors: | Lancey, C, Hamdan, S.M, De Biasio, A. | Deposit date: | 2019-06-19 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.86 Å) | Cite: | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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6S1O
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![BU of 6s1o by Molmil](/molmil-images/mine/6s1o) | Human polymerase delta holoenzyme Conformer 3 | Descriptor: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | Authors: | Lancey, C, Hamdan, S.M, De Biasio, A. | Deposit date: | 2019-06-19 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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5VU7
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![BU of 5vu7 by Molmil](/molmil-images/mine/5vu7) | TNA polymerase, open ternary complex | Descriptor: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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1WAF
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![BU of 1waf by Molmil](/molmil-images/mine/1waf) | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | Descriptor: | DNA POLYMERASE, GUANOSINE | Authors: | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | Deposit date: | 1997-04-13 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell(Cambridge,Mass.), 89, 1997
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1WAJ
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![BU of 1waj by Molmil](/molmil-images/mine/1waj) | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | Descriptor: | DNA POLYMERASE, GUANOSINE-5'-MONOPHOSPHATE | Authors: | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | Deposit date: | 1997-04-13 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell(Cambridge,Mass.), 89, 1997
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5MDN
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![BU of 5mdn by Molmil](/molmil-images/mine/5mdn) | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis | Descriptor: | DNA polymerase, MAGNESIUM ION | Authors: | Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. | Deposit date: | 2016-11-12 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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5N2E
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![BU of 5n2e by Molmil](/molmil-images/mine/5n2e) | Structure of the E9 DNA polymerase from vaccinia virus | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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6S1M
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![BU of 6s1m by Molmil](/molmil-images/mine/6s1m) | Human polymerase delta holoenzyme Conformer 1 | Descriptor: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | Authors: | Lancey, C, Hamdan, S.M, De Biasio, A. | Deposit date: | 2019-06-19 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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5N2H
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![BU of 5n2h by Molmil](/molmil-images/mine/5n2h) | Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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5N2G
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![BU of 5n2g by Molmil](/molmil-images/mine/5n2g) | Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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6TNZ
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![BU of 6tnz by Molmil](/molmil-images/mine/6tnz) | Human polymerase delta-FEN1-PCNA toolbelt | Descriptor: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | Authors: | Lancey, C, Hamdan, S.M, De Biasio, A. | Deposit date: | 2019-12-10 | Release date: | 2019-12-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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5VU9
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![BU of 5vu9 by Molmil](/molmil-images/mine/5vu9) | TNA polymerase, translocated product | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
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![BU of 5vu8 by Molmil](/molmil-images/mine/5vu8) | TNA polymerase, closed ternary complex | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU6
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![BU of 5vu6 by Molmil](/molmil-images/mine/5vu6) | |
7RSS
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![BU of 7rss by Molmil](/molmil-images/mine/7rss) | Kod-RI incorporating DNA, n+2 | Descriptor: | DNA polymerase, Primer, Template | Authors: | Hajjar, M, Chim, N, Chaput, J.C. | Deposit date: | 2021-08-11 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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7RSR
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![BU of 7rsr by Molmil](/molmil-images/mine/7rsr) | Kod-RI incorporating PMT, n+2 | Descriptor: | DNA polymerase, Primer, Template | Authors: | Hajjar, M, Chim, N, Chaput, J.C. | Deposit date: | 2021-08-11 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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6ISG
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![BU of 6isg by Molmil](/molmil-images/mine/6isg) | Structure of 9N-I DNA polymerase incorporation with dG in the active site | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*AP*CP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*G)-3'), ... | Authors: | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | Deposit date: | 2018-11-16 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.401 Å) | Cite: | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
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6ISF
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![BU of 6isf by Molmil](/molmil-images/mine/6isf) | Structure of 9N-I DNA polymerase incorporation with dT in the active site | Descriptor: | CALCIUM ION, DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*T)-3'), ... | Authors: | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | Deposit date: | 2018-11-16 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
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6ISH
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![BU of 6ish by Molmil](/molmil-images/mine/6ish) | Structure of 9N-I DNA polymerase incorporation with 3'-AL in the active site | Descriptor: | CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*(DAL))-3'), ... | Authors: | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | Deposit date: | 2018-11-16 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
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6IS7
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![BU of 6is7 by Molmil](/molmil-images/mine/6is7) | Structure of 9N-I DNA polymerase incorporation with dA in the active site | Descriptor: | CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*A)-3'), ... | Authors: | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | Deposit date: | 2018-11-15 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
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6ISI
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![BU of 6isi by Molmil](/molmil-images/mine/6isi) | Structure of 9N-I DNA polymerase incorporation with 3'-CL in the active site | Descriptor: | 3-[2-[2-(2-azanylethoxy)ethoxy]ethoxy]propanoic acid, CALCIUM ION, DNA (5'-D(P*AP*CP*GP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | Authors: | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | Deposit date: | 2018-11-16 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
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