PDB: 226262 resultsInfo pagesStatus searchChemie searchBIRD

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9JDV	Human URAT1 bound with Uric acid Descriptor: Solute carrier family 22 member 12, URIC ACID Authors: Wu, C, Xu, H.E. Deposit date: 2024-09-01 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs Biorxiv, 2024
9JDY	Human URAT1 bound with verinurad Descriptor: Solute carrier family 22 member 12, verinurad Authors: Wu, C, Xu, H.E. Deposit date: 2024-09-01 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs Biorxiv, 2024
8WQZ	X-ray Crystal Structure of Pseudoazurin Met16Gly variant Descriptor: COPPER (II) ION, DI(HYDROXYETHYL)ETHER, Pseudoazurin Authors: Sugai, A, Yamaguchi, T, Kohzuma, T. Deposit date: 2023-10-12 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.2 Å) Cite: X-ray Crystal Structure of Pseudoazurin Met16Gly variant To Be Published
9C88	Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Translocating a Portion of a Branched-Degron DHFR Substrate Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... Authors: Ghanbarpour, A, Sauer, R.T, Davis, J.H. Deposit date: 2024-06-12 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Cryo-EM structure of a fully-engaged DHFR-ssrA substrate and the AAA+ ClpXP protease To Be Published
8PVU	Cryo-EM structure of DHS-ERK2 complex with 1:1 stoichiometry refined in C1 symmetry Descriptor: Deoxyhypusine synthase, Mitogen-activated protein kinase 1 Authors: Kochanowski, P, Biela, A.P, Grudnik, P. Deposit date: 2023-07-18 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: ERK1/2 regulates the DHPS-eIF5A hypusination pathway in kinase activity-dependent and independent manners Cell Rep, 2024
8RCY	L-SIGN CRD in complex with Man84. Descriptor: 1-[[1-[(2S,3S,4R,5S,6R)-2-(2-chloroethyloxy)-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-1,2,3-triazol-4-yl]methyl]guanidine, C-type lectin domain family 4 member M, CALCIUM ION, ... Authors: Thepaut, M, Bouchikri, C, Pollastri, S, Bernardi, A, Fieschi, F. Deposit date: 2023-12-07 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Unprecedented selectivity for homologous lectin targets: differential targeting of the viral receptors L-SIGN and DC-SIGN. Chem Sci, 15, 2024
8RLU	TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 S3N peptide Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... Authors: Pengelly, R.J, Godinho, L.F. Deposit date: 2024-01-03 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (2.35 Å) Cite: TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 S3N peptide To Be Published
9BA1	Solution NMR structure of the human LETM1 F-EF-hand domain in the presence of calcium Descriptor: CALCIUM ION, Mitochondrial proton/calcium exchanger protein Authors: Lin, Q.T, Stathopulos, P.B. Deposit date: 2024-04-03 Release date: 2024-10-16 Method: SOLUTION NMR Cite: An AI-informed NMR structure reveals an extraordinary LETM1 F-EF-hand domain that functions as a two-way regulator of mitochondrial calcium. Structure, 2024
9D7K	Infectious B19V capsid Descriptor: Alpha-1-antichymotrypsin Authors: Lee, H, Hafenstein, S. Deposit date: 2024-08-16 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (3 Å) Cite: Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors To Be Published
9FMR	Structure of DDB1/Cdk12/Cyclin K with molecular glue SR-4835 Descriptor: Cyclin-K, Cyclin-dependent kinase 12, DNA damage-binding protein 1, ... Authors: Anand, K, Schmitz, M, Geyer, M. Deposit date: 2024-06-07 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Structure of DDB1/Cdk12/Cyclin K with molecular glue SR-4835 To Be Published
8WPN	Cryo-EM structure of the human TRPC4 in lipid nanodiscs Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... Authors: Won, J, Jeong, H, Lee, H.H. Deposit date: 2023-10-10 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (2.82 Å) Cite: Structure of a TRP channel To Be Published
9BI9	GII.4 Sydney 2012 Polymerase domain of ProPol precursor Descriptor: MAGNESIUM ION, RNA-dependent RNA polymerase domain of Protease-Polymerase precursor Authors: Eruera, A, Krause, K. Deposit date: 2024-04-23 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: Activity and Cryo-EM Structure of the Polymerase Domain of Human Norovirus ProPol To Be Published
9C27	Infectious B19V capsid Descriptor: Capsid protein 2 Authors: Lee, H, Hafenstein, S. Deposit date: 2024-05-30 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors To Be Published
8Q4Y	Beta-galactosidase from Bacillus circulans conformational state 1 Descriptor: beta-galactosidase Authors: Kascakova, B, Hovorkova, M, Petraskova, L, Novacek, J, Pinkas, D, Gardian, Z, Kren, V, Bojarova, P, Kuta Smatanova, I. Deposit date: 2023-08-07 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (4 Å) Cite: The variable structural flexibility of the Bacillus circulans beta-galactosidase isoforms determines their unique functionalities. Structure, 2024
8QDN	NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with7-fluoro-N,N-dimethyl-1-benzofuran-2-carboxamide Descriptor: 7-fluoranyl-~{N},~{N}-dimethyl-1-benzofuran-2-carboxamide, RASK GTPase (Fragment) Authors: Buetikofer, M, Orts, J. Deposit date: 2023-08-30 Release date: 2024-10-16 Method: SOLUTION NMR Cite: NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one To Be Published
8QE6	NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine Descriptor: 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, RASK GTPase (Fragment) Authors: Buetikofer, M, Orts, J. Deposit date: 2023-08-30 Release date: 2024-10-16 Method: SOLUTION NMR Cite: NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one To Be Published
8UEN	Crystal structure of Corynebacterium ulcerans endo-beta-N-acetylglucosaminidase catalytically inactive CU43 D187A-E189A at 2.3 A (P 21 21 2) Descriptor: Corynebacterial protease CP40 Authors: Sastre, D.E, Sultana, N, Sundberg, E.J. Deposit date: 2023-10-02 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of Corynebacterium ulcerans endo-beta-N-acetylglucosaminidase catalytically inactive CU43 D187A-E189A at 2.3 A (P21 21 2) To Be Published
8UGM	FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, boronic acid-based compound Z27 bound Descriptor: 1-benzothiophen-3-ylboronic acid, CALCIUM ION, Fluorophosphonate-binding serine hydrolase E Authors: Fellner, M. Deposit date: 2023-10-05 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, boronic acid-based compound Z27 bound To Be Published
8QMV	L2 forming RubisCO derived from ancestral sequence reconstruction of the last common ancestor of Form I'' and Form I RubisCOs Descriptor: 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, RubisCO large subunit Authors: Zarzycki, J, Schulz, L, Erb, T.J, Hochberg, G.K.A. Deposit date: 2023-09-25 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Layered entrenchment maintains essentiality in the evolution of Form I Rubisco complexes Biorxiv, 2024
8QPS	Deoxyribose-5-phosphate aldolase (DERA) from Geobacillus sp. Descriptor: Deoxyribose-phosphate aldolase Authors: Paakkonen, J, Hakulinen, N, Rouvinen, J. Deposit date: 2023-10-03 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Three-dimensional structure of deoxyribose phosphate aldolase (DERA) from thermophilic Geobacillus sp. To Be Published
8QQN	Portal protein of full Haloferax tailed virus 1. Descriptor: HK97 gp6-like/SPP1 gp15-like head-tail connector, MAGNESIUM ION, Portal protein Authors: Zhang, D, Daum, B, Isupov, M.N, McLaren, M. Deposit date: 2023-10-05 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (2.342 Å) Cite: CryoEM structure of Haloferax tailed virus 1 To Be Published
8R6X	Cryo-EM structure of a coxsackievirus A6 virus-like particle Descriptor: Genome polyprotein Authors: Giannopoulou, E.A, Jakobi, A.J. Deposit date: 2023-11-23 Release date: 2024-10-16 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Enterovirus-like particles can encapsidate viral RNA To Be Published
8RDO	Holomycin methyltransferase DtpM with SAH and XRD-271Me Descriptor: D-MALATE, DtpM, GLYCEROL, ... Authors: Huber, E.M, Groll, M. Deposit date: 2023-12-08 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification. Angew.Chem.Int.Ed.Engl., 2024
8RDL	Xenorhabdin methyltransferase XrdM with SAH Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, ToxA protein Authors: Huber, E.M, Groll, M. Deposit date: 2023-12-08 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification. Angew.Chem.Int.Ed.Engl., 2024
8RDM	Holomycin methyltransferase DtpM with SAH Descriptor: DtpM, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE Authors: Huber, E.M, Groll, M. Deposit date: 2023-12-08 Release date: 2024-10-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification. Angew.Chem.Int.Ed.Engl., 2024

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