9JDV

Human URAT1 bound with Uric acid

Summary for 9JDV

• Entry DOI: 10.2210/pdb9jdv/pdb
• EMDB information: 61399
• Descriptor: Solute carrier family 22 member 12, URIC ACID (3 entities in total)
• Functional Keywords: urat1, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 59839.94

Authors

Wu, C.,Zhang, C.,Jin, S.,Wang, J.J.,Jiang, Y.,Yang, D.,Xu, H.E. (deposition date: 2024-09-01, release date: 2024-10-16, Last modification date: 2024-10-30)

• Primary citation: Wu, C.,Zhang, C.,Jin, S.,Wang, J.J.,Dai, A.,Xu, J.,Zhang, H.,Yang, X.,He, X.,Yuan, Q.,Hu, W.,Xu, Y.,Wang, M.,Jiang, Y.,Yang, D.,Xu, H.E.; Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs; Biorxiv, 2024; DOI: 10.1101/2024.09.11.612394

Experimental method

ELECTRON MICROSCOPY (3.32 Å)