1HE3
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![BU of 1he3 by Molmil](/molmil-images/mine/1he3) | Human biliverdin IX beta reductase: NADP/mesobiliverdin IV alpha ternary complex | Descriptor: | BILIVERDIN IX BETA REDUCTASE, MESOBILIVERDIN IV ALPHA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M. | Deposit date: | 2000-11-18 | Release date: | 2001-02-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme Nat.Struct.Biol., 8, 2001
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1QSS
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![BU of 1qss by Molmil](/molmil-images/mine/1qss) | DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ... | Authors: | Li, Y, Mitaxov, V, Waksman, G. | Deposit date: | 1999-06-23 | Release date: | 1999-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
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1HE2
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![BU of 1he2 by Molmil](/molmil-images/mine/1he2) | Human biliverdin IX beta reductase: NADP/biliverdin IX alpha ternary complex | Descriptor: | BILIVERDIN IX BETA REDUCTASE, BILIVERDINE IX ALPHA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M. | Deposit date: | 2000-11-18 | Release date: | 2001-02-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme Nat.Struct.Biol., 8, 2001
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1AXG
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![BU of 1axg by Molmil](/molmil-images/mine/1axg) | CRYSTAL STRUCTURE OF THE VAL203->ALA MUTANT OF LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH COFACTOR NAD AND INHIBITOR TRIFLUOROETHANOL SOLVED TO 2.5 ANGSTROM RESOLUTION | Descriptor: | ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | Authors: | Colby, T.D, Chin, J.K, Bahnson, B.J, Goldstein, B.M, Klinman, J.P. | Deposit date: | 1997-10-15 | Release date: | 1998-04-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A link between protein structure and enzyme catalyzed hydrogen tunneling. Proc.Natl.Acad.Sci.USA, 94, 1997
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5JPQ
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![BU of 5jpq by Molmil](/molmil-images/mine/5jpq) | Cryo-EM structure of the 90S pre-ribosome | Descriptor: | 18S ribosomal RNA, Bms1, Emg1, ... | Authors: | Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R. | Deposit date: | 2016-05-04 | Release date: | 2016-07-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome. Cell, 166, 2016
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5KK1
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![BU of 5kk1 by Molmil](/molmil-images/mine/5kk1) | |
6O7Y
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![BU of 6o7y by Molmil](/molmil-images/mine/6o7y) | Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-4 | Descriptor: | 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(S)-({(2R,3R,4R,5R)-3-{[(R)-{[(2R,3R,4R,5R)-3-{[(S)-{[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-{[(S)-hydroxy{[(2R,3R,4R,5R)-3-hydroxy-4-methoxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methoxy}phosphoryl]oxy}-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-[6-(dimethylamino)-9H-purin-9-yl]-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-3H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION | Authors: | Guimaraes, B.G, Reolon, L.W. | Deposit date: | 2019-03-08 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4. Nucleic Acids Res., 47, 2019
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6O80
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![BU of 6o80 by Molmil](/molmil-images/mine/6o80) | |
1B7G
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![BU of 1b7g by Molmil](/molmil-images/mine/1b7g) | GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE | Descriptor: | PROTEIN (GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE), SULFATE ION | Authors: | Isupov, M.N, Littlechild, J.A. | Deposit date: | 1999-01-22 | Release date: | 1999-10-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus. J.Mol.Biol., 291, 1999
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6O7Z
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![BU of 6o7z by Molmil](/molmil-images/mine/6o7z) | Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-1 | Descriptor: | 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(S)-{[(R)-({(2R,3R,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-3-hydroxy-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION | Authors: | Guimaraes, B.G, Reolon, L.W. | Deposit date: | 2019-03-08 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4. Nucleic Acids Res., 47, 2019
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1AXE
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![BU of 1axe by Molmil](/molmil-images/mine/1axe) | CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL | Descriptor: | ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | Authors: | Colby, T.D, Chin, J.K, Goldstein, B.M. | Deposit date: | 1997-10-15 | Release date: | 1998-04-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A link between protein structure and enzyme catalyzed hydrogen tunneling. Proc.Natl.Acad.Sci.USA, 94, 1997
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1Q9H
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![BU of 1q9h by Molmil](/molmil-images/mine/1q9h) | 3-Dimensional structure of native Cel7A from Talaromyces emersonii | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, cellobiohydrolase I catalytic domain | Authors: | Grassick, A, Thompson, R, Murray, P.G, Collins, C.M, Byrnes, L, Tuohy, M.G, Birrane, G, Higgins, T.M. | Deposit date: | 2003-08-25 | Release date: | 2004-11-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii Eur.J.Biochem., 271, 2004
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1QXJ
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![BU of 1qxj by Molmil](/molmil-images/mine/1qxj) | Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus | Descriptor: | Glucose-6-phosphate isomerase, NICKEL (II) ION | Authors: | Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, T, Schonheit, P, Davies, C. | Deposit date: | 2003-09-07 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus J.Biol.Chem., 278, 2003
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7ASE
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![BU of 7ase by Molmil](/molmil-images/mine/7ase) | 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase | Descriptor: | 18S, 40S ribosomal protein S10, putative, ... | Authors: | Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. | Deposit date: | 2020-10-27 | Release date: | 2021-04-14 | Last modified: | 2021-04-21 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
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3BQ0
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![BU of 3bq0 by Molmil](/molmil-images/mine/3bq0) | Pre-insertion binary complex of Dbh DNA polymerase | Descriptor: | CALCIUM ION, DNA (5'-D(*DGP*DAP*DAP*DGP*DCP*DCP*DGP*DGP*DCP*DG)-3'), DNA (5'-D(*DT*DTP*DCP*DCP*DGP*DCP*DCP*DCP*DGP*DGP*DCP*DTP*DTP*DCP*DC)-3'), ... | Authors: | Pata, J.D, Wilson, R.C. | Deposit date: | 2007-12-19 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Mol.Cell, 29, 2008
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6YAL
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![BU of 6yal by Molmil](/molmil-images/mine/6yal) | Mammalian 48S late-stage initiation complex with beta-globin mRNA | Descriptor: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | Authors: | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | Deposit date: | 2020-03-12 | Release date: | 2020-04-08 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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1QHT
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![BU of 1qht by Molmil](/molmil-images/mine/1qht) | |
5JHK
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![BU of 5jhk by Molmil](/molmil-images/mine/5jhk) | X-ray structure of neuropilin-1 b1 domain complexed with Arg-6 ligand. | Descriptor: | N-(benzenecarbonyl)glycyl-L-arginine, Neuropilin-1 | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-04-21 | Release date: | 2017-05-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
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1QWQ
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![BU of 1qwq by Molmil](/molmil-images/mine/1qwq) | Solution structure of the monomeric N67D mutant of Bovine Seminal Ribonuclease | Descriptor: | Ribonuclease | Authors: | Avitabile, F, Alfano, C, Spadaccini, R, Crescenzi, O, D'Ursi, A.M, D'Alessio, G, Tancredi, T, Picone, D. | Deposit date: | 2003-09-03 | Release date: | 2003-09-16 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | THE SWAPPING OF TERMINAL ARMS IN RIBONUCLEASES: COMPARISON OF THE SOLUTION STRUCTURE OF MONOMERIC BOVINE SEMINAL AND PANCREATIC RIBONUCLEASES Biochemistry, 42, 2003
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1H8A
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![BU of 1h8a by Molmil](/molmil-images/mine/1h8a) | CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX3 | Descriptor: | CAAT/ENHANCER BINDING PROTEIN BETA, DNA(5'-(*CP*CP*AP*GP*TP*CP*CP*GP*TP*TP*AP* AP*GP*GP*AP*TP*TP*GP*CP*GP*CP*CP*AP*CP*AP*T)-3'), DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ... | Authors: | Tahirov, T.H, Ogata, K. | Deposit date: | 2001-01-31 | Release date: | 2002-01-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter Cell(Cambridge,Mass.), 108, 2002
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7RLO
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![BU of 7rlo by Molmil](/molmil-images/mine/7rlo) | Structure of the human eukaryotic translation initiation factor 2B (eIF2B) in complex with a viral protein NSs | Descriptor: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | Authors: | Wang, L, Schoof, M, Cogan, J, Lawrence, R, Boone, M, Wuerth, J, Frost, M, Walter, P. | Deposit date: | 2021-07-26 | Release date: | 2021-12-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun, 12, 2021
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4L8A
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![BU of 4l8a by Molmil](/molmil-images/mine/4l8a) | Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA | Descriptor: | 1,2-ETHANEDIOL, COENZYME A, N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine, ... | Authors: | Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-06-16 | Release date: | 2013-07-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J.Biol.Chem., 288, 2013
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9WGA
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![BU of 9wga by Molmil](/molmil-images/mine/9wga) | |
6YAN
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![BU of 6yan by Molmil](/molmil-images/mine/6yan) | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | Authors: | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | Deposit date: | 2020-03-12 | Release date: | 2020-04-08 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6WF5
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![BU of 6wf5 by Molmil](/molmil-images/mine/6wf5) | Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2) | Descriptor: | (2R)-2-hydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide, ACE-MET-LEU-GLY-PRO-NH2, N-alpha-acetyltransferase 50 | Authors: | Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E. | Deposit date: | 2020-04-03 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library. Acs Med.Chem.Lett., 11, 2020
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