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4IEA
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BU of 4iea by Molmil
14-3-3 isoform sigma in complex with a phosphorylated C-RAF peptide
Descriptor: 14-3-3 protein sigma, RAF proto-oncogene serine/threonine-protein kinase
Authors:Molzan, M, Ottmann, C.
Deposit date:2012-12-13
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers.
Acs Chem.Biol., 8, 2013
4IOF
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BU of 4iof by Molmil
Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)
Descriptor: Fab-bound IDE, heavy chain, light chain, ...
Authors:McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J.
Deposit date:2013-01-07
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.353 Å)
Cite:Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IOS
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BU of 4ios by Molmil
Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11.
Descriptor: BPP, GLYCEROL, Llama nanobody 11
Authors:Desmyter, A, Farenc, C, Mahony, J, Spinelli, S, Bebeacua, C, Blangy, S, Veesler, D, van Sinderen, D, Cambillau, C.
Deposit date:2013-01-08
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
2MUG
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BU of 2mug by Molmil
Protective cellular immunity against P. falciparum malaria merozoite is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex
Descriptor: Serine-repeat antigen protein
Authors:Patarroyo, M, Salazar, L, Cifuentes, G, Lozano, J, Delgado, G, Rivera, Z, Rosas, J, Vargas, L.
Deposit date:2014-09-09
Release date:2014-10-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Protective cellular immunity against P. falciparum malaria merozoites is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex.
Biochimie, 88, 2006
6VSB
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BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
Deposit date:2020-02-10
Release date:2020-02-26
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
3OC5
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BU of 3oc5 by Molmil
Crystal Structure of the vibrio cholerae secreted colonization factor TcpF
Descriptor: Toxin coregulated pilus biosynthesis protein F
Authors:Craig, L, Kolappan, S, Yuen, A.S.W.
Deposit date:2010-08-09
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site.
J.Mol.Biol., 409, 2011
3OC8
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BU of 3oc8 by Molmil
Crystal Structure of the C-terminal Domain of the Vibrio cholerae soluble colonization factor TcpF
Descriptor: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ...
Authors:Craig, L, Kolappan, S, Yuen, A.S.W.
Deposit date:2010-08-09
Release date:2011-04-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site.
J.Mol.Biol., 409, 2011
4UX8
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BU of 4ux8 by Molmil
RET recognition of GDNF-GFRalpha1 ligand by a composite binding site promotes membrane-proximal self-association
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF FAMILY RECEPTOR ALPHA-1, ...
Authors:Goodman, K, Kjaer, S, Beuron, F, Knowles, P, Nawrotek, A, Burns, E, Purkiss, A, George, R, Santoro, M, Morris, E.P, McDonald, N.Q.
Deposit date:2014-08-19
Release date:2014-10-01
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (24 Å)
Cite:Ret Recognition of Gdnf-Gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association.
Cell Rep., 8, 2014
4V86
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BU of 4v86 by Molmil
Structure-function Analysis of Receptor-binding in Adeno-Associated Virus Serotype 6 (AAV-6)
Descriptor: Capsid protein VP1
Authors:Xie, Q.
Deposit date:2011-09-13
Release date:2014-07-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure-function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6).
Virology, 420, 2011
1TCR
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BU of 1tcr by Molmil
MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garcia, K.C, Degano, M, Stanfield, R.L, Wilson, I.A.
Deposit date:1996-09-12
Release date:1997-03-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science, 274, 1996
1T2J
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BU of 1t2j by Molmil
Crystal structure of a Human VH domain
Descriptor: DI(HYDROXYETHYL)ETHER, M12-Variable Heavy domain
Authors:Gaur, R.K, Fischer, R, Hoffmann, K.M.V.
Deposit date:2004-04-21
Release date:2005-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a human VH domain at 1.5 angstrom
To be Published
5HCG
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BU of 5hcg by Molmil
CRYSTAL STRUCTURE OF FREE-CODV.
Descriptor: CODV heavy-chain, CODV light chain
Authors:Vallee, F, Dupuy, A, Rak, A.
Deposit date:2016-01-04
Release date:2016-03-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.
Mabs, 8, 2016
5V8O
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BU of 5v8o by Molmil
Discovery of a high affinity inhibitor of cGAS
Descriptor: 5-phenyltetrazolo[1,5-a]pyrimidin-7-ol, Cyclic GMP-AMP synthase, ZINC ION
Authors:Hall, J.
Deposit date:2017-03-22
Release date:2017-09-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
PLoS ONE, 12, 2017
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
Descriptor: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
Authors:James, L.C, Kiss, L.
Deposit date:2022-06-14
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
3T1P
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BU of 3t1p by Molmil
Crystal structure of an alpha-1-antitrypsin trimer
Descriptor: Alpha-1-antitrypsin
Authors:Huntington, J.A, Yamasaki, M.
Deposit date:2011-07-22
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
EMBO Rep., 12, 2011
3S96
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BU of 3s96 by Molmil
Crystal structure of 3B5H10
Descriptor: 3B5H10 FAB heavy chain, 3B5H10 FAB light chain
Authors:Weisgraber, K, Peters-Libeu, C, Rutenber, E, Newhouse, Y, Finkbeiner, S.
Deposit date:2011-05-31
Release date:2012-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
3VI4
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BU of 3vi4 by Molmil
Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Nagae, M, Nogi, T, Takagi, J.
Deposit date:2011-09-21
Release date:2012-02-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor
J.Cell Biol., 197, 2012
3VI3
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BU of 3vi3 by Molmil
Crystal structure of alpha5beta1 integrin headpiece (ligand-free form)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Nagae, M, Nogi, T, Takagi, J.
Deposit date:2011-09-21
Release date:2012-02-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor
J.Cell Biol., 197, 2012
8TTN
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BU of 8ttn by Molmil
PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E)
Descriptor: Microtubule-associated protein tau
Authors:El Mammeri, N, Dregni, A.J, Duan, P, Hong, M.
Deposit date:2023-08-14
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTL
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BU of 8ttl by Molmil
AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E)
Descriptor: Microtubule-associated protein tau
Authors:El Mammeri, N, Dregni, A.J, Duan, P, Hong, M.
Deposit date:2023-08-14
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UKV
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BU of 8ukv by Molmil
Crystal structure of nanobody/VHH domain of 34E5 in complex with the extracellular region of the epidermal growth factor variant III (EGFRvIII)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Stayrook, S.E, Ferguson, K.M, Bagchi, A.
Deposit date:2023-10-15
Release date:2024-06-19
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structural insights into the role and targeting of EGFRvIII.
Structure, 2024
1DKK
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BU of 1dkk by Molmil
BOBWHITE QUAIL LYSOZYME WITH NITRATE
Descriptor: LYSOZYME, NITRATE ION
Authors:Jeffrey, P.D, Sheriff, S.
Deposit date:1996-01-10
Release date:1996-07-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
1DKJ
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BU of 1dkj by Molmil
BOBWHITE QUAIL LYSOZYME
Descriptor: LYSOZYME
Authors:Jeffrey, P.D, Sheriff, S.
Deposit date:1996-01-10
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
2LHV
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BU of 2lhv by Molmil
Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat
Descriptor: MUC2 Mucin Domain Peptide
Authors:Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D.
Deposit date:2011-08-18
Release date:2012-04-04
Last modified:2012-06-27
Method:SOLUTION NMR
Cite:Deciphering structural elements of mucin glycoprotein recognition.
Acs Chem.Biol., 7, 2012
1JYI
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BU of 1jyi by Molmil
CONCANAVALIN A/12-MER PEPTIDE COMPLEX
Descriptor: 12-mer peptide, CALCIUM ION, Concanavalin-Br, ...
Authors:Jain, D, Kaur, K.J, Sundaravadivel, B, Salunke, D.M.
Deposit date:2001-09-12
Release date:2002-09-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and Functional Consequences of Peptide-carbohydrate Mimicry. Crystal Structure of a Carbohydrate-mimicking Peptide Bound to Concanavalin A.
J.Biol.Chem., 275, 2000

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