8TTL
AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E)
Summary for 8TTL
| Entry DOI | 10.2210/pdb8ttl/pdb |
| EMDB information | 41610 |
| Descriptor | Microtubule-associated protein tau (1 entity in total) |
| Functional Keywords | tau, amyloid fibril, phosphomimetic, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 241115.60 |
| Authors | El Mammeri, N.,Dregni, A.J.,Duan, P.,Hong, M. (deposition date: 2023-08-14, release date: 2024-06-26) |
| Primary citation | Mammeri, N.E.,Dregni, A.J.,Duan, P.,Hong, M. Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation. Proc.Natl.Acad.Sci.USA, 121:e2316175121-e2316175121, 2024 Cited by PubMed: 38408247DOI: 10.1073/pnas.2316175121 PDB entries with the same primary citation |
| Experimental method |
Structure validation
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