PDB: 13422 resultsInfo pagesStatus searchChemie searchBIRD

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3FJC	Crystal structure of L44W mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Blaber, M, Lee, J. Deposit date: 2008-12-14 Release date: 2009-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
3FGM	Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Blaber, M, Lee, J. Deposit date: 2008-12-06 Release date: 2009-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
4MVJ	2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate. Descriptor: ACETATE ION, ACETYLPHOSPHATE, CHLORIDE ION, ... Authors: Minasov, G, Kuhn, M, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2013-09-24 Release date: 2014-04-23 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. Plos One, 9, 2014
4K6A	Revised Crystal Structure of apo-form of Triosephosphate Isomerase (tpiA) from Escherichia coli at 1.8 Angstrom Resolution. Descriptor: SODIUM ION, Triosephosphate isomerase Authors: Minasov, G, Kuhn, M, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2013-04-15 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PLoS ONE, 9, 2014
5KJH	Crystal structure of an active polycomb repressive complex 2 in the stimulated state Descriptor: Peptide H3K27me3, Putative uncharacterized protein,Zinc finger domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Jiao, L, Liu, X. Deposit date: 2016-06-20 Release date: 2017-04-19 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2". Science, 354, 2016
7L1G	PRMT5-MEP50 Complexed with SAM Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Methylosome protein 50, ... Authors: Palte, R.L. Deposit date: 2020-12-14 Release date: 2021-04-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Development of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4- b ]furan Nucleoside Analogues. J.Org.Chem., 86, 2021
2CXV	Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-Derived betaLactone: Selective Crystallization and High-resolution Structure of the His-102 Adduct Descriptor: N-[(BENZYLOXY)CARBONYL]-L-ALANINE, Probable protein P3C Authors: Yin, J, Bergmann, E.M, Cherney, M.M, Lall, M.S, Jain, R.P, Vederas, J.C, James, M.N.G. Deposit date: 2005-07-01 Release date: 2005-12-27 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived beta-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site J.MOL.BIOL., 354, 2005
2QFL	Structure of SuhB: Inositol monophosphatase and extragenic suppressor from E. coli Descriptor: ACETATE ION, ETHYL ACETATE, Inositol-1-monophosphatase Authors: Wang, Y, Stieglitz, K.A, Bubunenko, M, Court, D, Stec, B, Roberts, M.F. Deposit date: 2007-06-27 Release date: 2007-07-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli. J.Biol.Chem., 282, 2007
6XL6	Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPo Descriptor: CHAPSO, MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2020-06-28 Release date: 2021-04-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
3QB7	Interleukin-4 mutant RGA bound to cytokine receptor common gamma Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... Authors: Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C. Deposit date: 2011-01-12 Release date: 2012-04-25 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.245 Å) Cite: Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nat.Chem.Biol., 8, 2012
3QB1	Interleukin-2 mutant D10 Descriptor: Interleukin-2 Authors: Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C. Deposit date: 2011-01-12 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Exploiting a natural conformational switch to engineer an interleukin-2 'superkine' Nature, 484, 2012
6BCB	A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... Authors: Sternweis, P.C, Chen, Z. Deposit date: 2017-10-20 Release date: 2017-12-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.401 Å) Cite: Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase. Data Brief, 17, 2018
6BCA	A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ... Authors: Sternweis, P.C, Chen, Z. Deposit date: 2017-10-20 Release date: 2017-12-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.995 Å) Cite: Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase. Data Brief, 17, 2018
5MXO	Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide stabilized by Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Andrei, S, Ottmann, C, Leysen, S. Deposit date: 2017-01-24 Release date: 2017-11-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591, 2017
1NCR	The structure of Rhinovirus 16 when complexed with pleconaril, an antiviral compound Descriptor: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, MYRISTIC ACID, ZINC ION, ... Authors: Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. Deposit date: 2002-12-05 Release date: 2003-12-16 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
6W0L	Henipavirus W protein interacts with 14-3-3 to modulate host gene expression Descriptor: 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide Authors: Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C. Deposit date: 2020-03-01 Release date: 2020-04-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression. J.Virol., 94, 2020
3RI4	Ets1 cooperative binding to widely separated sites on promoter DNA Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA Authors: Babayeva, N.D, Mino, K, Tahirov, T.H. Deposit date: 2011-04-12 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA. Plos One, 7, 2012
3K44	Crystal Structure of Drosophila melanogaster Pur-alpha Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Purine-rich binding protein-alpha, ... Authors: Graebsch, A, Roche, S, Niessing, D. Deposit date: 2009-10-05 Release date: 2009-10-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-ray structure of Pur-alpha reveals a Whirly-like fold and an unusual nucleic-acid binding surface Proc.Natl.Acad.Sci.USA, 106, 2009
1ROQ	Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3 Descriptor: 5'-R(*GP*GP*UP*AP*UP*CP*AP*CP*GP*GP*UP*AP*CP*C)-3' Authors: Du, Z, Yu, J, Andino, R, James, T.L. Deposit date: 2003-12-02 Release date: 2004-05-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3 Biochemistry, 42, 2003
7KID	PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 72 Descriptor: (1S,2R,3aR,4S,6aR)-4-[(2-amino-3,5-difluoroquinolin-7-yl)methyl]-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydropentalene-1,6a(1H)-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ... Authors: Palte, R.L. Deposit date: 2020-10-23 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J.Med.Chem., 64, 2021
7KIC	PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 34 Descriptor: (2R,3R,3aS,6S,6aR)-6-[(2-amino-3-bromoquinolin-7-yl)oxy]-2-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydro-3aH-cyclopenta[b]furan-3,3a-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ... Authors: Palte, R.L. Deposit date: 2020-10-23 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.43 Å) Cite: The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J.Med.Chem., 64, 2021
7KIB	PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 4 Descriptor: (2R,3R,3aS,6S,6aR)-6-[(2-amino-3-bromoquinolin-7-yl)oxy]-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydro-3aH-cyclopenta[b]furan-3,3a-diol, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Palte, R.L, Hayes, R.P. Deposit date: 2020-10-23 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.52 Å) Cite: The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J.Med.Chem., 64, 2021
1ND3	The structure of HRV16, when complexed with pleconaril, an antiviral compound Descriptor: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, ZINC ION, coat protein VP1, ... Authors: Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. Deposit date: 2002-12-06 Release date: 2003-12-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
1ND2	The structure of Rhinovirus 16 Descriptor: MYRISTIC ACID, ZINC ION, coat protein VP1, ... Authors: Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. Deposit date: 2002-12-06 Release date: 2003-12-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
1NCQ	The structure of HRV14 when complexed with pleconaril, an antiviral compound Descriptor: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, COAT PROTEIN VP1, COAT PROTEIN VP2, ... Authors: Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. Deposit date: 2002-12-05 Release date: 2003-12-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004

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