1NCQ

The structure of HRV14 when complexed with pleconaril, an antiviral compound

Summary for 1NCQ

Related1NA1
DescriptorCOAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ... (6 entities in total)
Functional Keywordsrhinovirus 14, hrv, pleconaril, icosahedral virus, virus
Biological sourceHuman rhinovirus 14
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) P03303 P03303 P03303 P03303
Total number of polymer chains4
Total molecular weight94863.88
Authors
Zhang, Y.,Simpson, A.A.,Bator, C.M.,Chakravarty, S.,Pevear, D.C.,Skochko, G.A.,Tull, T.M.,Diana, G.,Rossmann, M.G. (deposition date: 2002-12-05, release date: 2003-12-16, Last modification date: 2011-07-13)
Primary citation
Zhang, Y.,Simpson, A.A.,Ledford, R.M.,Bator, C.M.,Chakravarty, S.,Skochko, G.A.,Demenczuk, T.M.,Watanyar, A.,Pevear, D.C.,Rossmann, M.G.
Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78:11061-11069, 2004
PubMed: 15452226 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.78.20.11061-11069.2004
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers150.8%8.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution