8YBK
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![BU of 8ybk by Molmil](/molmil-images/mine/8ybk) | Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2024-02-14 | Release date: | 2024-07-24 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes Cells, 29, 2024
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8YBJ
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![BU of 8ybj by Molmil](/molmil-images/mine/8ybj) | Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2024-02-14 | Release date: | 2024-07-24 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes Cells, 29, 2024
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8W0Z
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![BU of 8w0z by Molmil](/molmil-images/mine/8w0z) | Human LCAD complexed with Lauric Acid | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LAURIC ACID, Long-chain specific acyl-CoA dehydrogenase, ... | Authors: | Xia, C, Kim, J.J.P. | Deposit date: | 2024-02-14 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
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8W0T
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![BU of 8w0t by Molmil](/molmil-images/mine/8w0t) | Human LCAD | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, mitochondrial | Authors: | Xia, C, Kim, J.J.P. | Deposit date: | 2024-02-14 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
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8W0U
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![BU of 8w0u by Molmil](/molmil-images/mine/8w0u) | Human LCAD complexed with Acetoacetyl Coenzyme A | Descriptor: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ... | Authors: | Xia, C, Kim, J.J.P. | Deposit date: | 2024-02-14 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases. Sci Rep, 14, 2024
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8W12
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![BU of 8w12 by Molmil](/molmil-images/mine/8w12) | Cryo-EM structure of VP3-VP6 heterohexamer | Descriptor: | Core protein VP3, VP6 | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-14 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
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8S0M
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![BU of 8s0m by Molmil](/molmil-images/mine/8s0m) | Crystal structure of the HKU1 receptor binding domain in complex with TMPRSS2 and the nanobody A01 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A01, ... | Authors: | Duquerroy, S, Fernandez, I, Rey, F. | Deposit date: | 2024-02-14 | Release date: | 2024-06-26 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus. Cell, 187, 2024
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8S0L
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![BU of 8s0l by Molmil](/molmil-images/mine/8s0l) | Crystal structure of the TMPRSS2 zymogen in complex with the nanobody A07 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Nanobody A07, ... | Authors: | Duquerroy, S, Fernandez, I, Rey, F. | Deposit date: | 2024-02-14 | Release date: | 2024-06-26 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus. Cell, 187, 2024
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8S0N
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![BU of 8s0n by Molmil](/molmil-images/mine/8s0n) | |
8W0K
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![BU of 8w0k by Molmil](/molmil-images/mine/8w0k) | |
8RZV
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![BU of 8rzv by Molmil](/molmil-images/mine/8rzv) | |
8W08
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![BU of 8w08 by Molmil](/molmil-images/mine/8w08) | Crystal Structure of the worst case reconstruction of the ancestral triosephosphate isomerase of the last opisthokont common ancestor obtained by maximum likelihood | Descriptor: | FLUORIDE ION, Triosephosphate isomerase | Authors: | Perez-Nino, J.A, Rodriguez-Romero, A, Guerra-Borrego, Y, Fernandez-Velasco, D.A. | Deposit date: | 2024-02-13 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Stable monomers in the ancestral sequence reconstruction of the last opisthokont common ancestor of dimeric triosephosphate isomerase. Protein Sci., 33, 2024
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8W05
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![BU of 8w05 by Molmil](/molmil-images/mine/8w05) | |
8W06
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![BU of 8w06 by Molmil](/molmil-images/mine/8w06) | Crystal Structure of the reconstruction of the ancestral triosephosphate isomerase of the last opisthokont common ancestor obtained by maximum likelihood with PGH | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACETIC ACID, ... | Authors: | Perez-Nino, J.A, Rodriguez-Romero, A, Guerra-Borrego, Y, Fernandez-Velasco, D.A. | Deposit date: | 2024-02-13 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Stable monomers in the ancestral sequence reconstruction of the last opisthokont common ancestor of dimeric triosephosphate isomerase. Protein Sci., 33, 2024
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8YB7
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![BU of 8yb7 by Molmil](/molmil-images/mine/8yb7) | SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C3 symmetry) | Descriptor: | Non-structural protein 4, Papain-like protease nsp3 | Authors: | Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. | Deposit date: | 2024-02-12 | Release date: | 2024-06-19 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Molecular architecture of coronavirus double-membrane vesicle pore complex. Nature, 2024
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8RZE
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![BU of 8rze by Molmil](/molmil-images/mine/8rze) | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 10 | Descriptor: | 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanylmethyl]-5-pyridin-3-yl-benzoic acid, ... | Authors: | Kalnins, G. | Deposit date: | 2024-02-12 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 10 To Be Published
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8RZC
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![BU of 8rzc by Molmil](/molmil-images/mine/8rzc) | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11 | Descriptor: | 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanylmethyl]-5-imidazol-1-yl-benzoic acid, ... | Authors: | Kalnins, G. | Deposit date: | 2024-02-12 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11 To Be Published
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8RZD
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![BU of 8rzd by Molmil](/molmil-images/mine/8rzd) | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 9 | Descriptor: | 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanylmethyl]-5-(3-hydroxyphenyl)benzoic acid, ... | Authors: | Kalnins, G. | Deposit date: | 2024-02-12 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 9 To Be Published
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8VZR
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![BU of 8vzr by Molmil](/molmil-images/mine/8vzr) | Crystal structure of dehaloperoxidase A in complex with substrate 4-bromo-o-cresol | Descriptor: | 4-bromo-2-methylphenol, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase A, ... | Authors: | Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. | Deposit date: | 2024-02-12 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 63, 2024
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8RZB
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![BU of 8rzb by Molmil](/molmil-images/mine/8rzb) | IL-1beta in complex with covalent DEL hit | Descriptor: | 8-[4-methyl-3-(trifluoromethyl)phenyl]-2-[[(7S)-7-(2-morpholin-4-ylethylcarbamoyl)-4-(phenylsulfonyl)-1,4-diazepan-1-yl]carbonyl]imidazo[1,2-a]pyridine-6-carboxylic acid, Interleukin-1 beta | Authors: | Rondeau, J.-M, Lehmann, S. | Deposit date: | 2024-02-12 | Release date: | 2024-05-22 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.836 Å) | Cite: | Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
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8YB5
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![BU of 8yb5 by Molmil](/molmil-images/mine/8yb5) | SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry) | Descriptor: | Non-structural protein 4, Papain-like protease nsp3 | Authors: | Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. | Deposit date: | 2024-02-11 | Release date: | 2024-06-19 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Molecular architecture of coronavirus double-membrane vesicle pore complex. Nature, 2024
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8YB6
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![BU of 8yb6 by Molmil](/molmil-images/mine/8yb6) | Type I-EHNH Cascade complex | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | Authors: | Li, Z. | Deposit date: | 2024-02-11 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 84, 2024
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8VZM
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![BU of 8vzm by Molmil](/molmil-images/mine/8vzm) | DNA Ligase 1 captured with pre-step 3 ligation at the rA:T nicksite | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2024-02-11 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8VZL
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![BU of 8vzl by Molmil](/molmil-images/mine/8vzl) | DNA Ligase 1 captured with pre-step 3 ligation at the rG:C nicksite | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2024-02-11 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8VZ9
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![BU of 8vz9 by Molmil](/molmil-images/mine/8vz9) | Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex | Descriptor: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Ciacchi, L, Rossjohn, J, Awad, W. | Deposit date: | 2024-02-11 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil. J.Biol.Chem., 300, 2024
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