8Y0W
| dormant ribosome with eIF5A, eEF2 and SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes. Front Mol Biosci, 11, 2024
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8Y0G
| Human beta-catenin crystal structure | Descriptor: | Catenin beta-1 | Authors: | Tim, F. | Deposit date: | 2024-01-22 | Release date: | 2024-03-13 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal protein of human Beta-catenin To Be Published
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8XZ7
| FGFR1 kinase domain with a covalent inhibitor 10h | Descriptor: | 5-azanyl-3-[2-[4,6-bis(fluoranyl)-2-methyl-3~{H}-benzimidazol-5-yl]ethynyl]-1-[[3-(prop-2-enoylamino)phenyl]methyl]pyrazole-4-carboxamide, Fibroblast growth factor receptor 1, SULFATE ION | Authors: | Chen, X.J, Chen, Y.H. | Deposit date: | 2024-01-20 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors. Eur.J.Med.Chem., 275, 2024
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8XZ2
| The structural model of a homodimeric D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria | Descriptor: | D-alanyl-D-alanine dipeptidase | Authors: | Konuma, T, Takai, T, Tsuchiya, C, Nishida, M, Hashiba, M, Yamada, Y, Shirai, H, Motoda, Y, Nagadoi, A, Chikaishi, E, Akagi, K, Akashi, S, Yamazaki, T, Akutsu, H, Oe, A, Ikegami, T. | Deposit date: | 2024-01-20 | Release date: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria. Protein Sci., 33, 2024
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8XYN
| Structure of the engineered retro-aldolase RA95.5-8 | Descriptor: | 4-[dodecyl(dimethyl)-$l^{4}-azanyl]butanoic acid, retro-aldolase RA95.5-8 | Authors: | Kunthic, T, Yu, M.Z, Xiang, Z. | Deposit date: | 2024-01-20 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Artificial Enzyme for Asymmetric Nitrocyclopropanation of alpha , beta-Unsaturated Aldehydes-Design and Evolution. Angew.Chem.Int.Ed.Engl., 63, 2024
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8XY0
| Activity-stability trade-off observed in variants at position 315 of the GH10 xylanase XynR | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Endo-1,4-beta-xylanase A | Authors: | Nakamura, T, Takita, T, Mizutani, K, Mikami, B, Nakamura, S, Yasukawa, K. | Deposit date: | 2024-01-19 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Activity-stability trade-off observed in variants at position 315 of the GH10 xylanase XynR. Sci Rep, 14, 2024
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8XXW
| Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, M2-7-Heavy chain, M2-7-Light chain, ... | Authors: | Liu, C, Xie, Y. | Deposit date: | 2024-01-19 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses. Cell Rep, 43, 2024
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8XXN
| Cryo-EM structure of the human 43S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXM
| Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXL
| Cryo-EM structure of the human 40S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXA
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8XX9
| Rhodothermus marinus alpha-amylase RmGH13_47A CBM48-A-B-C domains | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Tonozuka, T. | Deposit date: | 2024-01-18 | Release date: | 2024-02-07 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for the recognition of alpha-1,6-branched alpha-glucan by GH13_47 alpha-amylase from Rhodothermus marinus. Proteins, 92, 2024
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8XX0
| Crystal structure of anti-IgE antibody HMK-12 Fab complexed with IgE F(ab')2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SPE7 immunoglobulin E F(ab')2 heavy chain, ... | Authors: | Hirano, T, Koyanagi, A, Kasai, M, Okumura, K. | Deposit date: | 2024-01-17 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Allosteric inhibition of IgE-Fc epsilon RI interactions by simultaneous targeting of IgE F(ab')2 epitopes. Commun Biol, 7, 2024
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8XW9
| Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and UDP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, OXALATE ION, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2024-01-16 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis of Nucleotide Selectivity in Pyruvate Kinase. J.Mol.Biol., 436, 2024
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8XW8
| Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and GDP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2024-01-16 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of Nucleotide Selectivity in Pyruvate Kinase. J.Mol.Biol., 436, 2024
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8XW7
| Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and ADP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2024-01-16 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis of Nucleotide Selectivity in Pyruvate Kinase. J.Mol.Biol., 436, 2024
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8XW6
| Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and ATP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2024-01-16 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural Basis of Nucleotide Selectivity in Pyruvate Kinase. J.Mol.Biol., 436, 2024
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8XW4
| Cryo-EM structure of TMEM63B-Digitonin state | Descriptor: | CSC1-like protein 2 | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XW3
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8XW2
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8XW1
| Cryo-EM structure of OSCA1.2-V335W-DDM state | Descriptor: | Calcium permeable stress-gated cation channel 1 | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.49 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XW0
| Cryo-EM structure of OSCA3.1-GDN state | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XVZ
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8XVY
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8XVX
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