8XZ2

The structural model of a homodimeric D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria

Summary for 8XZ2

• Entry DOI: 10.2210/pdb8xz2/pdb
• Related: 1r44
• Descriptor: D-alanyl-D-alanine dipeptidase (1 entity in total)
• Functional Keywords: acid-selective unlabeling, antimicrobial resistance, homodimer, residual dipolar coupling (rdc), transfer cross saturation (tcs), vancomycin-resistant enterococci, vanx, metal binding protein
• Biological source: Enterococcus faecium
• Total number of polymer chains: 2
• Total formula weight: 46816.34

Authors

Konuma, T.,Takai, T.,Tsuchiya, C.,Nishida, M.,Hashiba, M.,Yamada, Y.,Shirai, H.,Motoda, Y.,Nagadoi, A.,Chikaishi, E.,Akagi, K.,Akashi, S.,Yamazaki, T.,Akutsu, H.,Oe, A.,Ikegami, T. (deposition date: 2024-01-20, release date: 2024-05-22)

• Primary citation: Konuma, T.,Takai, T.,Tsuchiya, C.,Nishida, M.,Hashiba, M.,Yamada, Y.,Shirai, H.,Motoda, Y.,Nagadoi, A.,Chikaishi, E.,Akagi, K.I.,Akashi, S.,Yamazaki, T.,Akutsu, H.,Ikegami, T.; Analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria.; Protein Sci., 33:e5002-e5002, 2024; PubMed: 38723146; DOI: 10.1002/pro.5002

Experimental method

SOLUTION NMR