7V8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v8f by Molmil](/molmil-images/mine/7v8f) | Crystal structure of UBE2L3 bound to HOIP RING1 domain. | Descriptor: | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-22 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
1F44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f44 by Molmil](/molmil-images/mine/1f44) | CRYSTAL STRUCTURE OF TRIMERIC CRE RECOMBINASE-LOX COMPLEX | Descriptor: | CRE RECOMBINASE, DNA (5'- D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*GP*C)-3'), DNA (5'-D(*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3') | Authors: | Baldwin, E.P, Woods, K.C. | Deposit date: | 2000-06-07 | Release date: | 2001-10-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Quasi-equivalence in site-specific recombinase structure and function: crystal structure and activity of trimeric Cre recombinase bound to a three-way Lox DNA junction. J.Mol.Biol., 313, 2001
|
|
8BJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bja by Molmil](/molmil-images/mine/8bja) | |
3UIN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uin by Molmil](/molmil-images/mine/3uin) | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 | Descriptor: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | Authors: | Gareau, J.R, Reverter, D, Lima, C.D. | Deposit date: | 2011-11-05 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
|
|
3UIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uip by Molmil](/molmil-images/mine/3uip) | Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | Descriptor: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | Authors: | Gareau, J.R, Reverter, D, Lima, C.D. | Deposit date: | 2011-11-05 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
|
|
3UIO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uio by Molmil](/molmil-images/mine/3uio) | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | Descriptor: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | Authors: | Gareau, J.R, Reverter, D, Lima, C.D. | Deposit date: | 2011-11-05 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
|
|
8F8U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f8u by Molmil](/molmil-images/mine/8f8u) | |
6SQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sqp by Molmil](/molmil-images/mine/6sqp) | Crystal structure of Cat MDM2-S429E RING domain homodimer | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
|
|
3G7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g7s by Molmil](/molmil-images/mine/3g7s) | |
3V7C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v7c by Molmil](/molmil-images/mine/3v7c) | Cystal structure of SaBPL in complex with inhibitor | Descriptor: | 5'-deoxy-2',3'-O-(1-methylethylidene)-5'-(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)adenosine, Biotin ligase | Authors: | Yap, M.Y, Pendini, N.R. | Deposit date: | 2011-12-20 | Release date: | 2012-04-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
|
|
8FI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fi3 by Molmil](/molmil-images/mine/8fi3) | |
4AYC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ayc by Molmil](/molmil-images/mine/4ayc) | RNF8 RING domain structure | Descriptor: | CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF8, GLYCEROL, ... | Authors: | Mattiroli, F, Vissers, J.H.A, Van Dijk, W.J, Ikpa, P, Citterio, E, Vermeulen, W, Marteijn, J.A, Sixma, T.K. | Deposit date: | 2012-06-20 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rnf168 Ubiquitinates K13-15 on H2A/H2Ax to Drive DNA Damage Signaling Cell(Cambridge,Mass.), 150, 2012
|
|
4XZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xzf by Molmil](/molmil-images/mine/4xzf) | Crystal structure of HIRAN domain of human HLTF in complex with DNA | Descriptor: | (DA)(DC)(DC)(DG)(DC)(DC)(DG)(DG)(DG)(DT)(DG)(DC)(DC), Helicase-like transcription factor | Authors: | Hishiki, A, Hashimoto, H. | Deposit date: | 2015-02-04 | Release date: | 2015-04-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance J.Biol.Chem., 290, 2015
|
|
6NVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nvp by Molmil](/molmil-images/mine/6nvp) | Crystal structure of Pseudomonas putida nuclease MPE | Descriptor: | MANGANESE (II) ION, Nuclease MPE | Authors: | Goldgur, Y, Shuman, S, Ejaz, A. | Deposit date: | 2019-02-05 | Release date: | 2019-03-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Activity and structure ofPseudomonas putidaMPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster. J.Biol.Chem., 294, 2019
|
|
6NVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nvo by Molmil](/molmil-images/mine/6nvo) | Crystal structure of Pseudomonas putida nuclease MPE | Descriptor: | MANGANESE (II) ION, Nuclease MPE | Authors: | Goldgur, Y, Shuman, S, Ejaz, A. | Deposit date: | 2019-02-05 | Release date: | 2019-03-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.196 Å) | Cite: | Activity and structure ofPseudomonas putidaMPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster. J.Biol.Chem., 294, 2019
|
|
1E8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e8c by Molmil](/molmil-images/mine/1e8c) | Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli | Descriptor: | 2,6-DIAMINOPIMELIC ACID, CHLORIDE ION, UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ... | Authors: | Gordon, E.J, Chantala, L, Dideberg, O. | Deposit date: | 2000-09-19 | Release date: | 2001-09-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Udp-N-Acetylmuramoyl-L-Alanyl-D-Glutamate: Meso-Diaminopimelate Ligase from Escherichia Coli J.Biol.Chem., 276, 2001
|
|
3TII
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tii by Molmil](/molmil-images/mine/3tii) | Tubulin tyrosine ligase | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ttl protein | Authors: | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | Deposit date: | 2011-08-20 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin. Nat.Struct.Mol.Biol., 18, 2011
|
|
5NWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nwl by Molmil](/molmil-images/mine/5nwl) | Crystal structure of a human RAD51-ATP filament. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 1, MAGNESIUM ION | Authors: | Pellegrini, L, Moschetti, T. | Deposit date: | 2017-05-06 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.93 Å) | Cite: | Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA. EMBO J., 37, 2018
|
|
5TVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tvq by Molmil](/molmil-images/mine/5tvq) | |
3TIN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tin by Molmil](/molmil-images/mine/3tin) | Tubulin tyrosine ligase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ttl protein | Authors: | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | Deposit date: | 2011-08-20 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin. Nat.Struct.Mol.Biol., 18, 2011
|
|
3TIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tig by Molmil](/molmil-images/mine/3tig) | Tubulin tyrosine ligase | Descriptor: | MAGNESIUM ION, Ttl protein | Authors: | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | Deposit date: | 2011-08-20 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin. Nat.Struct.Mol.Biol., 18, 2011
|
|
8FVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fvi by Molmil](/molmil-images/mine/8fvi) | Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 | Descriptor: | Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... | Authors: | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-01-19 | Release date: | 2023-09-06 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
|
|
6OET
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oet by Molmil](/molmil-images/mine/6oet) | Cryo-EM structure of mouse RAG1/2 STC complex | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (39-MER), ... | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | Deposit date: | 2019-03-27 | Release date: | 2020-01-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | How mouse RAG recombinase avoids DNA transposition. Nat.Struct.Mol.Biol., 27, 2020
|
|
3RPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rpg by Molmil](/molmil-images/mine/3rpg) | Bmi1/Ring1b-UbcH5c complex structure | Descriptor: | E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ... | Authors: | Bentley, M.L, Dong, K.C, Cochran, A.G. | Deposit date: | 2011-04-26 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6485 Å) | Cite: | Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Embo J., 30, 2011
|
|
6CIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cij by Molmil](/molmil-images/mine/6cij) | Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | Deposit date: | 2018-02-24 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
|
|