4GY7
| Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution | Descriptor: | 1,2-ETHANEDIOL, ACETONE, BETA-MERCAPTOETHANOL, ... | Authors: | Begum, A, Banumathi, S, Choudhary, M.I, Betzel, C. | Deposit date: | 2012-09-05 | Release date: | 2012-11-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.492 Å) | Cite: | Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution To be Published
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4LGY
| Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. | Deposit date: | 2013-06-30 | Release date: | 2013-12-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
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1DGO
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4P58
| Crystal structure of mouse comt bound to an inhibitor | Descriptor: | 1',3'-dimethyl-1H,1'H-3,4'-bipyrazole, Catechol O-methyltransferase | Authors: | Lanier, M. | Deposit date: | 2014-03-15 | Release date: | 2014-06-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT). J.Med.Chem., 57, 2014
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4LMS
| Light harvesting complex PC645 from the cryptophyte Chroomonas sp. CCMP270 | Descriptor: | 15,16-DIHYDROBILIVERDIN, HEXAETHYLENE GLYCOL, PHYCOCYANOBILIN, ... | Authors: | Harrop, S.J, Wilk, K.E, Curmi, P.M.G. | Deposit date: | 2013-07-11 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Single-residue insertion switches the quaternary structure and exciton states of cryptophyte light-harvesting proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LM6
| Light harvesting complex PC612 from the cryptophyte Hemiselmis virescens M1635 | Descriptor: | 15,16-DIHYDROBILIVERDIN, PHYCOCYANOBILIN, cryptophyte phycocyanin alpha chain, ... | Authors: | Harrop, S.J, Wilk, K.E, Curmi, P.M.G. | Deposit date: | 2013-07-10 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Single-residue insertion switches the quaternary structure and exciton states of cryptophyte light-harvesting proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LKA
| Crystal Structure of MOZ double PHD finger histone H3K9ac complex | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | Deposit date: | 2013-07-07 | Release date: | 2013-10-16 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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1ZG5
| NarL complexed to narG-89 promoter palindromic tail-to-tail DNA site | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*CP*CP*CP*TP*AP*TP*AP*GP*GP*GP*GP*TP*AP*CP*G)-3', Nitrate/nitrite response regulator protein narL, SULFATE ION | Authors: | Maris, A.E, Kaczor-Grzeskowiak, M, Ma, Z, Kopka, M.L, Gunsalus, R.P, Dickerson, R.E. | Deposit date: | 2005-04-20 | Release date: | 2005-11-22 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Primary and Secondary Modes of DNA Recognition by the NarL Two-Component Response Regulator. Biochemistry, 44, 2005
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4LMX
| Light harvesting complex PE555 from the cryptophyte Hemiselmis andersenii CCMP644 | Descriptor: | 15,16-DIHYDROBILIVERDIN, PHYCOERYTHROBILIN, cryptophyte phycoerythrin (alpha-1 chain), ... | Authors: | Harrop, S.J, Wilk, K.E, Curmi, P.M.G. | Deposit date: | 2013-07-11 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Single-residue insertion switches the quaternary structure and exciton states of cryptophyte light-harvesting proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LDC
| Crystal Structure of DOC2B C2B domain | Descriptor: | CALCIUM ION, CITRATE ANION, Double C2-like domain-containing protein beta | Authors: | Giladi, M, Almagor, L, Hirsch, J.A. | Deposit date: | 2013-06-24 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.264 Å) | Cite: | The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis. J.Mol.Biol., 425, 2013
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1DL6
| SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN | Descriptor: | TRANSCRIPTION FACTOR II B (TFIIB), ZINC ION | Authors: | Chen, H.-T, Legault, P, Glushka, J, Omichinski, J.G, Scott, R.A. | Deposit date: | 1999-12-08 | Release date: | 2000-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription. Protein Sci., 9, 2000
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4E4K
| Crystal Structure of PPARgamma with the ligand JO21 | Descriptor: | (2S)-3-phenyl-2-{[2'-(propan-2-yl)biphenyl-4-yl]oxy}propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Loiodice, F, Fracchiolla, G, Laghezza, A, Carbonara, G, Piemontese, L, Lavecchia, A, Novellino, E. | Deposit date: | 2012-03-13 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | New 2-(Aryloxy)-3-phenylpropanoic Acids as Peroxisome Proliferator-Activated Receptor alpha/gamma Dual Agonists Able To Upregulate Mitochondrial Carnitine Shuttle System Gene Expression. J.Med.Chem., 56, 2013
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4E4Q
| Crystal structure of PPARgamma with the ligand FS214 | Descriptor: | (2R)-3-phenyl-2-{[2'-(propan-2-yl)biphenyl-4-yl]oxy}propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Loiodice, F, Fracchiolla, G, Laghezza, A, Carbonara, G, Piemontese, L, Lavecchia, A, Novellino, E. | Deposit date: | 2012-03-13 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | New 2-(Aryloxy)-3-phenylpropanoic Acids as Peroxisome Proliferator-Activated Receptor alpha/gamma Dual Agonists Able To Upregulate Mitochondrial Carnitine Shuttle System Gene Expression. J.Med.Chem., 56, 2013
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4R4R
| Crystal structure of chimeric beta-lactamase cTEM-19m at 1.2 angstrom resolution | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | Deposit date: | 2014-08-19 | Release date: | 2015-11-11 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Sci Rep, 9, 2019
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4IWM
| Crystal Structure of the Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii (in P21 form) | Descriptor: | UPF0135 protein MJ0927 | Authors: | Kuan, S.M, Chen, S.C, Yang, C.S, Chen, Y.R, Liu, Y.H, Chen, Y. | Deposit date: | 2013-01-24 | Release date: | 2014-01-29 | Last modified: | 2021-04-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a conserved hypothetical protein MJ0927 from Methanocaldococcus jannaschii reveals a novel quaternary assembly in the Nif3 family. Biomed Res Int, 2014, 2014
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4CA5
| Human Angiotensin converting enzyme in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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4R4S
| Crystal structure of chimeric beta-lactamase cTEM-19m at 1.1 angstrom resolution | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | Deposit date: | 2014-08-19 | Release date: | 2015-11-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Sci Rep, 9, 2019
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4R7P
| Human UDP-glucose pyrophosphorylase isoform 1 in complex with UDP-glucose | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ... | Authors: | Fuehring, J, Cramer, J.T, Schneider, J, Baruch, P, Gerardy-Schahn, R, Fedorov, R. | Deposit date: | 2014-08-28 | Release date: | 2015-04-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | A Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism. Sci Rep, 5
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4HE2
| Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ... | Authors: | Shi, R, Zhu, D.W, Lin, S.X. | Deposit date: | 2012-10-03 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway. Plos One, 8, 2013
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1YCN
| X-RAY STRUCTURE OF ANNEXIN FROM ARABIDOPSIS THALIANA GENE AT1G35720 | Descriptor: | putative Ca2+-dependent membrane-binding protein annexin | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2004-12-22 | Release date: | 2005-01-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | X-RAY STRUCTURE OF ANNEXIN FROM ARABIDOPSIS THALIANA GENE AT1G35720 To be published
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4H1M
| Crystal structure of PYK2 with the indole 10c | Descriptor: | 7-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)-N-(propan-2-yl)-1H-indole-2-carboxamide, Protein-tyrosine kinase 2-beta | Authors: | Han, S. | Deposit date: | 2012-09-10 | Release date: | 2012-11-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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1YCC
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4LLB
| Crystal Structure of MOZ double PHD finger histone H3K14ac complex | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | Deposit date: | 2013-07-09 | Release date: | 2013-10-16 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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2A6K
| Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR | Descriptor: | DODECAPEPTIDE: SLGDNLTNHNLR, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain | Authors: | Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M. | Deposit date: | 2005-07-03 | Release date: | 2006-06-13 | Last modified: | 2018-03-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response. Immunity, 24, 2006
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4L78
| Xenon Trapping and Statistical Coupling Analysis Uncover Regions Important for Structure and Function of Multidomain Protein StPurL | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. | Deposit date: | 2013-06-13 | Release date: | 2013-12-11 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
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