8Q63
| Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2023-08-10 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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7XUR
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7Y9Y
| Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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7Y9X
| Structure of the Cas7-11-Csx29-guide RNA complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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3OTD
| Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative | Descriptor: | IODIDE ION, tRNA(His) guanylyltransferase | Authors: | Hyde, S.J, Eckenroth, B.E, Doublie, S. | Deposit date: | 2010-09-11 | Release date: | 2010-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
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3OTB
| Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRIPHOSPHATE, ... | Authors: | Hyde, S.J, Eckenroth, B.E, Doublie, S. | Deposit date: | 2010-09-11 | Release date: | 2010-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
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8AP1
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-09 | Release date: | 2023-08-23 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8ATV
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 5-mer RNA, pppGpGpApApA (IC5) | Descriptor: | DNA (36-MER), DNA-directed RNA polymerase, mitochondrial, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-24 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8ATW
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 6-mer RNA, pppGpGpApApApU (IC6) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-24 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8ATT
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer RNA, pppGpGpUpA (IC4) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-24 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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1AJF
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8C5U
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG (IC8) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2023-01-10 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8C5S
| Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer RNA, pppGpGpUpApApApU (IC7) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2023-01-10 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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1XSU
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1XST
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1NGM
| Crystal structure of a yeast Brf1-TBP-DNA ternary complex | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*AP*AP*AP*AP*AP*AP*AP*TP*GP*TP*TP*TP*TP*TP*T)-3', Transcription factor IIIB BRF1 subunit, ... | Authors: | Juo, Z.S, Kassavetis, G.A, Wang, J, Geiduschek, E.P, Sigler, P.B. | Deposit date: | 2002-12-17 | Release date: | 2003-03-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of a transcription factor IIIB core interface ternary complex Nature, 422, 2003
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5NOH
| HRSV M2-1 core domain | Descriptor: | Transcription elongation factor M2-1 | Authors: | Josts, I, Almeida Hernandez, Y, Molina, I.G, de Prat-Gay, G, Tidow, H. | Deposit date: | 2017-04-12 | Release date: | 2018-01-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5NKX
| HRSV M2-1 core domain, P3221 crystal form | Descriptor: | M2-1 | Authors: | Almeida Hernandez, Y, Josts, I, Molina, I.G, de Pray-Gay, G, Tidow, H. | Deposit date: | 2017-04-03 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.00008678 Å) | Cite: | Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5HCI
| GPN-loop GTPase Npa3 in complex with GDP | Descriptor: | GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | Deposit date: | 2016-01-04 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
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5HCN
| GPN-loop GTPase Npa3 in complex with GMPPCP | Descriptor: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | Deposit date: | 2016-01-04 | Release date: | 2016-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
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4PUF
| Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1 | Descriptor: | E3 ubiquitin-protein ligase SlrP, Thioredoxin | Authors: | Zouhir, S, Bernal-Bayard, J, Cordero-Alba, M, Cardenal-Munoz, E, Guimaraes, B, Lazar, N, Ramos-Morales, F, Nessler, S. | Deposit date: | 2014-03-13 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.296 Å) | Cite: | The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family. Biochem.J., 464, 2014
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1PLQ
| CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA | Descriptor: | MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) | Authors: | Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. | Deposit date: | 1995-01-02 | Release date: | 1995-03-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
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1PLR
| CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA | Descriptor: | PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) | Authors: | Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. | Deposit date: | 1995-01-02 | Release date: | 1995-03-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
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8TDZ
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2VOO
| Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN | Authors: | Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. | Deposit date: | 2008-02-19 | Release date: | 2008-05-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
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