PDB: 657 resultsInfo pagesStatus searchChemie searchBIRD

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2HE4	The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif Descriptor: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2 Authors: Papagrigoriou, E, Elkins, J.M, Berridge, G, Gileady, O, Colebrook, S, Gileadi, C, Salah, E, Savitsky, P, Pantic, N, Gorrec, F, Bunkoczi, G, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Doyle, D.A, Structural Genomics Consortium (SGC) Deposit date: 2006-06-21 Release date: 2006-07-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16, 2007
2GZV	The cystal structure of the PDZ domain of human PICK1 Descriptor: PRKCA-binding protein Authors: Debreczeni, J.E, Elkins, J.M, Yang, X, Berridge, G, Bray, J, Colebrook, S, Smee, C, Savitsky, P, Gileadi, O, Turnbull, A, von Delft, F, Doyle, D.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC) Deposit date: 2006-05-12 Release date: 2006-07-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.12 Å) Cite: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16, 2007
4WSI	Crystal Structure of PALS1/Crb complex Descriptor: MAGUK p55 subfamily member 5, Protein crumbs Authors: Wei, Z, Li, Y, Zhang, M. Deposit date: 2014-10-28 Release date: 2014-11-26 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc.Natl.Acad.Sci.USA, 111, 2014
7M4R	Structural basis for SARS-CoV-2 envelope protein in recognition of human cell junction protein PALS1 Descriptor: Envelope small membrane protein, MAGUK p55 subfamily member 5 Authors: Liu, Q, Chai, J. Deposit date: 2021-03-22 Release date: 2021-03-31 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.65 Å) Cite: Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1. Nat Commun, 12, 2021
5V6T	The Plexin D1 intracellular region in complex with GIPC1 Descriptor: PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION Authors: Shang, G, Zhang, X. Deposit date: 2017-03-17 Release date: 2017-05-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.189 Å) Cite: Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
5WQL	Structure of a PDZ-protease bound to a substrate-binding adaptor Descriptor: ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA, LEU-SER-ARG-SER, ... Authors: Su, M.Y, Chang, C.I. Deposit date: 2016-11-27 Release date: 2017-11-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc Nat Commun, 8, 2017
6IQQ	Crystal structure of Prc with S452I and L252Y mutations in complex with NlpI Descriptor: CALCIUM ION, Lipoprotein NlpI, Tail-specific protease Authors: Chueh, C.K, Chang, C.I. Deposit date: 2018-11-08 Release date: 2019-07-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6IRD	Complex structure of INADL PDZ89 and PLCb4 C-terminal CC-PBM Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, GOLD ION, InaD-like protein Authors: Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. Deposit date: 2018-11-12 Release date: 2019-01-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.813 Å) Cite: An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors. Elife, 7, 2018
6IRE	Complex structure of INAD PDZ45 and NORPA CC-PBM Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein Authors: Ye, F, Li, J, Deng, X, Liu, W, Zhang, M. Deposit date: 2018-11-12 Release date: 2019-01-23 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.25 Å) Cite: An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors. Elife, 7, 2018
6IQR	Crystal structure of Prc with S452I and L252Y mutations Descriptor: Tail-specific protease Authors: Chueh, C.K, Chang, C.I. Deposit date: 2018-11-08 Release date: 2019-07-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6IQS	Crystal structure of Prc with L245A and L340G mutations in complex with NlpI Descriptor: Lipoprotein NlpI, Tail-specific protease Authors: Chuech, C.K, Chang, C.I. Deposit date: 2018-11-08 Release date: 2019-07-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6JJL	Crystal structure of the DegP dodecamer with a modulator Descriptor: CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy. Commun Biol, 3, 2020
6JJK	Crystal structure of the DegP dodecamer with a modulator Descriptor: CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy Commun Biol, 3, 2020
6JJO	Crystal structure of the DegP dodecamer with a modulator Descriptor: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.157 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy Commun Biol, 3, 2020
7W6X	Crystal structure of E. coli RseP in complex with batimastat Descriptor: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Regulator of sigma-E protease RseP, ZINC ION Authors: Takanuki, K, Imaizumi, Y, Nogi, T. Deposit date: 2021-12-02 Release date: 2022-09-07 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8, 2022
7YKG	Crystal structure of MAGI2 PDZ0-GK/pSGEF complex Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF Authors: Zhang, M, Lin, L, Zhu, J. Deposit date: 2022-07-22 Release date: 2023-08-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
4A9G	Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein Descriptor: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ Authors: Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. Deposit date: 2011-11-26 Release date: 2012-01-11 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
7YKI	Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide Descriptor: GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... Authors: Zhang, M, Lin, L, Zhu, J. Deposit date: 2022-07-22 Release date: 2023-08-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
7YKF	Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex Descriptor: Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Authors: Zhang, M, Lin, L, Zhu, J. Deposit date: 2022-07-22 Release date: 2023-08-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
7YKH	Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide Descriptor: GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... Authors: Zhang, M, Lin, L, Zhu, J. Deposit date: 2022-07-22 Release date: 2023-08-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
4A8C	Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with a binding peptide Descriptor: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ Authors: Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. Deposit date: 2011-11-20 Release date: 2012-01-11 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
5E6P	PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11 Authors: Pascoe, H.G, Zhang, X. Deposit date: 2015-10-10 Release date: 2015-11-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.215 Å) Cite: Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF. Proc.Natl.Acad.Sci.USA, 112, 2015
6SAK	Structure of the OTULINcat C129A - SNX27 PDZ domain complex. Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-27, ... Authors: Elliott, P.R, Komander, D. Deposit date: 2019-07-17 Release date: 2019-10-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Regulation of the endosomal SNX27-retromer by OTULIN. Nat Commun, 10, 2019
1KY9	Crystal Structure of DegP (HtrA) Descriptor: PROTEASE DO Authors: Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T. Deposit date: 2002-02-04 Release date: 2002-04-03 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine. Nature, 416, 2002
3MH6	HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues Descriptor: DIISOPROPYL PHOSPHONATE, Protease do Authors: Krojer, T, Sawa, J, Huber, R, Clausen, T. Deposit date: 2010-04-07 Release date: 2010-06-30 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.6 Å) Cite: HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010

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