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7NTF
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BU of 7ntf by Molmil
Cryo-EM structure of unliganded O-GlcNAc transferase
Descriptor: Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Meek, R.W, Blaza, J.N, Davies, G.J.
Deposit date:2021-03-09
Release date:2021-11-17
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (5.32 Å)
Cite:Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT.
Nat Commun, 12, 2021
6TNT
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BU of 6tnt by Molmil
SUMOylated apoAPC/C with repositioned APC2 WHB domain
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Barford, D, Yatskevich, S.
Deposit date:2019-12-10
Release date:2021-01-13
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
3LCA
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BU of 3lca by Molmil
Structure of Tom71 complexed with Hsp70 Ssa1 C terminal tail indicating conformational plasticity
Descriptor: GLYCEROL, Heat shock protein SSA1, Protein TOM71
Authors:Li, J.Z, Sha, B.D.
Deposit date:2010-01-10
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
3NF1
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BU of 3nf1 by Molmil
Crystal structure of the TPR domain of kinesin light chain 1
Descriptor: Kinesin light chain 1
Authors:Tong, Y, Tempel, W, Shen, L, Shen, Y, Nedyalkova, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-06-09
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the TPR domain of kinesin light chain 1
to be published
7AI4
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BU of 7ai4 by Molmil
Crystal structure of the KLC1-TPR domain truncated from its nonTPR region ([A1-B6]-Delta-nonTPR fragment)
Descriptor: Isoform C of Kinesin light chain 1,Isoform C of Kinesin light chain 1
Authors:Menetrey, J, Llinas, P.
Deposit date:2020-09-26
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Structural investigations of the dynamics of the TPR domain of kinesin light chain
To Be Published
7AIE
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BU of 7aie by Molmil
Crystal structure of a truncated form of the KLC1-TPR domain ([A1-B5] fragment) - Monoclinic crystal form
Descriptor: Kinesin light chain 1, MAGNESIUM ION
Authors:Menetrey, J, Llinas, P.
Deposit date:2020-09-27
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.287 Å)
Cite:Structural investigations of the dynamics of the TPR domain of kinesin light chain
To Be Published
2NC9
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BU of 2nc9 by Molmil
Apo solution structure of Hop TPR2A
Descriptor: Stress-induced-phosphoprotein 1
Authors:Darby, J.F, Vidler, L.R, Simpson, P.J, Matthews, S.J, Sharp, S.Y, Pearl, L.H, Hoelder, S, Workman, P.
Deposit date:2016-03-23
Release date:2017-03-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Sci Rep, 10, 2020
5G05
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BU of 5g05 by Molmil
Cryo-EM structure of combined apo phosphorylated APC
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
Deposit date:2016-03-16
Release date:2016-05-25
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5FJY
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BU of 5fjy by Molmil
Crystal structure of mouse kinesin light chain 2 (residues 161-480)
Descriptor: KINESIN LIGHT CHAIN 2, UNKNOWN PEPTIDE
Authors:Pernigo, S, Yip, Y.Y, Sanger, A, Xu, M, Dodding, M.P, Steiner, R.A.
Deposit date:2015-10-14
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4 Å)
Cite:The Light Chains of Kinesin-1 are Autoinhibited.
Proc.Natl.Acad.Sci.USA, 113, 2016
5OJ8
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BU of 5oj8 by Molmil
Crystal structure of the KLC1-TPR domain ([A1-B5] fragment)
Descriptor: Kinesin light chain 1, PHOSPHATE ION
Authors:Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J.
Deposit date:2017-07-20
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.
PLoS ONE, 12, 2017
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
3VTY
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BU of 3vty by Molmil
Crystal structure of MamA
Descriptor: CHLORIDE ION, MamA
Authors:Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
Deposit date:2012-06-08
Release date:2012-10-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
3VTX
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BU of 3vtx by Molmil
Crystal structure of MamA protein
Descriptor: GLYCEROL, MamA
Authors:Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
Deposit date:2012-06-08
Release date:2012-10-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
3ZFW
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BU of 3zfw by Molmil
Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide
Descriptor: KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2
Authors:Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P.
Deposit date:2012-12-12
Release date:2013-04-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Kinesin-1:Cargo Recognition.
Science, 340, 2013
6EOU
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BU of 6eou by Molmil
O-GlcNAc transferase TPR domain with the intellectual disability associated mutation L254F
Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Gundogdu, M, van Aalten, D.M.F.
Deposit date:2017-10-10
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix.
Cell Chem Biol, 25, 2018
6EJN
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BU of 6ejn by Molmil
The KLC2 TPR domain bound to the JIP3 leucine zipper domain
Descriptor: C-Jun-amino-terminal kinase-interacting protein 3, Kinesin light chain 2
Authors:Cockburn, J, Hesketh, S.J, Way, M.
Deposit date:2017-09-22
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3.
Structure, 26, 2018
6FO1
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BU of 6fo1 by Molmil
Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ...
Authors:Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O.
Deposit date:2018-02-05
Release date:2018-04-04
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
6FUZ
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BU of 6fuz by Molmil
Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1
Descriptor: GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody
Authors:Pernigo, S, Dodding, M.P, Steiner, R.A.
Deposit date:2018-02-28
Release date:2018-05-02
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
6FV0
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BU of 6fv0 by Molmil
Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA
Descriptor: DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody
Authors:Pernigo, S, Dodding, M.P, Steiner, R.A.
Deposit date:2018-02-28
Release date:2018-03-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
8DTG
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BU of 8dtg by Molmil
Cryo-EM structure of Arabidopsis SPY alternative conformation 1
Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
Deposit date:2022-07-25
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTI
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BU of 8dti by Molmil
Cryo-EM structure of Arabidopsis SPY in complex with GDP-fucose
Descriptor: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
Deposit date:2022-07-25
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTH
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BU of 8dth by Molmil
Cryo-EM structure of Arabidopsis SPY alternative conformation 2
Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
Deposit date:2022-07-25
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTF
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BU of 8dtf by Molmil
Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
Deposit date:2022-07-25
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
3CVQ
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BU of 3cvq by Molmil
Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (7-SKL)
Descriptor: GLYCEROL, PTS1 peptide 7-SKL (Ac-SNRWSKL), Peroxisome targeting signal 1 receptor PEX5
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-18
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
8EBF
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BU of 8ebf by Molmil
C-terminal (TPR) domain of LIC11990 from Leptospira interrogans
Descriptor: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL
Authors:Larrieux, N, Buschiazzo, A.
Deposit date:2022-08-31
Release date:2022-09-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990)
To Be Published

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