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2KMP
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Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
1DS3
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CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I
Descriptor: OVOMUCOID
Authors:Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2000-01-06
Release date:2001-01-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2M5X
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BU of 2m5x by Molmil
Novel method of protein purification for structural research. Example of ultra high resolution structure of SPI-2 inhibitor by X-ray and NMR spectroscopy.
Descriptor: Silk protease inhibitor 2
Authors:Lenarcic Zivkovic, M, Dvornyk, A, Kludkiewicz, B, Kopera, E, Zagorski-Ostoja, W, Grzelak, K, Zhukov, I, Bal, W.
Deposit date:2013-03-12
Release date:2014-03-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
2N71
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NMR structure of CmPI-II, a serin protease inhibitor isolated from mollusk Cenchitis muricatus
Descriptor: Protease inhibitor 2
Authors:Cabrera-Munoz, A, Rojas, L, Alonso del Rivero Antigua, M, Pires, J.
Deposit date:2015-09-01
Release date:2016-09-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of CmPI-II, a non-classical Kazal protease inhibitor: Understanding its conformational dynamics and subtilisin A inhibition.
J.Struct.Biol., 206, 2019
2OVO
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BU of 2ovo by Molmil
THE CRYSTAL AND MOLECULAR STRUCTURE OF THE THIRD DOMAIN OF SILVER PHEASANT OVOMUCOID (OMSVP3)
Descriptor: OVOMUCOID THIRD DOMAIN
Authors:Bode, W, Epp, O.
Deposit date:1985-06-11
Release date:1985-11-08
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal and molecular structure of the third domain of silver pheasant ovomucoid (OMSVP3).
Eur.J.Biochem., 147, 1985
2LEO
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BU of 2leo by Molmil
Solution structure of esophageal cancer-related gene 2
Descriptor: Serine protease inhibitor Kazal-type 7
Authors:Feng, Y, Geng, Y, Wang, J.
Deposit date:2011-06-20
Release date:2012-05-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure note: human esophageal cancer-related gene 2
J.Biomol.Nmr, 53, 2012
2N52
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The solution structure of the kallikrein inhibitor SPINK6
Descriptor: Serine protease inhibitor Kazal-type 6
Authors:Grotzinger, J.
Deposit date:2015-07-06
Release date:2016-03-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The solution structure of the kallikrein-related peptidases inhibitor SPINK6.
Biochem.Biophys.Res.Commun., 471, 2016
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
1TUR
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BU of 1tur by Molmil
SOLUTION STRUCTURE OF TURKEY OVOMUCOID THIRD DOMAIN AS DETERMINED FROM NUCLEAR MAGNETIC RESONANCE DATA
Descriptor: OVOMUCOID
Authors:Krezel, A.M, Darba, P, Robertson, A.D, Fejzo, J, Macura, S, Markley, J.L.
Deposit date:1994-07-06
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of turkey ovomucoid third domain as determined from nuclear magnetic resonance data.
J.Mol.Biol., 242, 1994
1TUS
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BU of 1tus by Molmil
SOLUTION STRUCTURE OF REACTIVE-SITE HYDROLYZED TURKEY OVOMUCOID THIRD DOMAIN BY NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY METHODS
Descriptor: OVOMUCOID
Authors:Walkenhorst, W.F, Krezel, A.M, Rhyu, G.I, Markley, J.L.
Deposit date:1994-07-06
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of reactive-site hydrolyzed turkey ovomucoid third domain by nuclear magnetic resonance and distance geometry methods.
J.Mol.Biol., 242, 1994
1UVF
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BU of 1uvf by Molmil
Solution Structure of the structured part of the 15th Domain of LEKTI
Descriptor: SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
Authors:Vitzithum, K, Roesch, P, Marx, U.C.
Deposit date:2004-01-20
Release date:2005-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
Biochemistry, 43, 2004
1UVG
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Solution structure of the 15th Domain of LEKTI
Descriptor: SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
Authors:Vitzithum, K, Roesch, P, Marx, U.C.
Deposit date:2004-01-20
Release date:2005-04-14
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
Biochemistry, 43, 2004
6KBR
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BU of 6kbr by Molmil
Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
Descriptor: GLYCEROL, K41043, Kallikrein-4
Authors:Kawaguchi, Y, Nishimiya, D.
Deposit date:2019-06-26
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
7E50
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BU of 7e50 by Molmil
Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
Descriptor: AAEL006007-PA, GLYCEROL, Plasminogen, ...
Authors:Varsha, A.W, Jobichen, C, Mok, Y.K.
Deposit date:2021-02-16
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
2F3C
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BU of 2f3c by Molmil
Crystal structure of infestin 1, a Kazal-type serineprotease inhibitor, in complex with trypsin
Descriptor: CALCIUM ION, Cationic trypsin, SULFATE ION, ...
Authors:Campos, I.T.N, Tanaka, A.S, Barbosa, J.A.R.G.
Deposit date:2005-11-20
Release date:2006-12-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure.
Acta Crystallogr.,Sect.D, 68, 2012
7QE8
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BU of 7qe8 by Molmil
Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE9
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BU of 7qe9 by Molmil
Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
1AN1
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BU of 1an1 by Molmil
LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX
Descriptor: CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR
Authors:Priestle, J.P, Di Marco, S.
Deposit date:1997-06-26
Release date:1998-07-01
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure, 5, 1997
1BMO
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BU of 1bmo by Molmil
BM-40, FS/EC DOMAIN PAIR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BM-40, CALCIUM ION
Authors:Hohenester, E, Maurer, P, Timpl, R.
Deposit date:1997-03-25
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.
EMBO J., 16, 1997
1YU6
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BU of 1yu6 by Molmil
Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex
Descriptor: CALCIUM ION, Ovomucoid, Subtilisin Carlsberg
Authors:Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2005-02-11
Release date:2005-05-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
3SGB
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BU of 3sgb by Molmil
STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
Descriptor: PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3)
Authors:Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G.
Deposit date:1983-01-21
Release date:1983-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
3SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
Descriptor: Ovomucoid, PHOSPHATE ION, Streptogrisin B
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2003-08-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2SGP
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PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Descriptor: OVOMUCOID INHIBITOR, PHOSPHATE ION, PROTEINASE B
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2001-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Descriptor: Ovomucoid, PHOSPHATE ION, Streptogrisin B
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2003-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2SGE
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GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
Descriptor: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2003-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
Protein Sci., 4, 1995

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數據於2024-05-01公開中

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