1P98
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4UEJ
| Closed state of galactitol-1-phosphate 5-dehydrogenase from E. coli in complex with glycerol. | Descriptor: | GALACTITOL-1-PHOSPHATE 5-DEHYDROGENASE, GLYCEROL, ZINC ION | Authors: | Benavente, R, Esteban-Torres, M, Kohring, G.W, Cortes-Cabrera, A, Gago, F, Acebron, I, de las Rivas, B, Munoz, R, Mancheno, J.M. | Deposit date: | 2014-12-18 | Release date: | 2015-07-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Enantioselective Oxidation of Galactitol 1-Phosphate by Galactitol-1-Phosphate 5-Dehydrogenase from Escherichia Coli Acta Crystallogr.,Sect.D, 71, 2015
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4UEO
| Open state of galactitol-1-phosphate 5-dehydrogenase from E. coli, with zinc in the catalytic site. | Descriptor: | GALACTITOL-1-PHOSPHATE 5-DEHYDROGENASE, ZINC ION | Authors: | Benavente, R, Esteban-Torres, M, Kohring, G.W, Cortes-Cabrera, A, Gago, F, Acebron, I, de las Rivas, B, Munoz, R, Mancheno, J.M. | Deposit date: | 2014-12-18 | Release date: | 2015-07-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enantioselective Oxidation of Galactitol 1-Phosphate by Galactitol-1-Phosphate 5-Dehydrogenase from Escherichia Coli Acta Crystallogr.,Sect.D, 71, 2015
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6RW4
| Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2019-06-03 | Release date: | 2020-06-03 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Distinct pre-initiation steps in human mitochondrial translation. Nat Commun, 11, 2020
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7DVQ
| Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | Authors: | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | Deposit date: | 2021-01-14 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of the activated human minor spliceosome. Science, 371, 2021
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7QH7
| Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | Deposit date: | 2021-12-10 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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6RW5
| Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF2 and IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2019-06-03 | Release date: | 2020-06-03 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Distinct pre-initiation steps in human mitochondrial translation. Nat Commun, 11, 2020
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6S01
| Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | Deposit date: | 2019-06-13 | Release date: | 2019-12-18 | Last modified: | 2020-01-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
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7D6F
| The crystal structure of ARMS-PBM/MAGI2-PDZ4 | Descriptor: | GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ... | Authors: | Ye, J, Zhang, Y, Zhong, Z, Wang, C. | Deposit date: | 2020-09-30 | Release date: | 2020-11-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode. Neurochem.Int., 149, 2021
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2FPF
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1VIW
| TENEBRIO MOLITOR ALPHA-AMYLASE-INHIBITOR COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, ALPHA-AMYLASE-INHIBITOR, ... | Authors: | Nahoum, V, Egloff, M.P, Payan, F. | Deposit date: | 1998-07-21 | Release date: | 1999-07-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A plant-seed inhibitor of two classes of alpha-amylases: X-ray analysis of Tenebrio molitor larvae alpha-amylase in complex with the bean Phaseolus vulgaris inhibitor. Acta Crystallogr.,Sect.D, 55, 1999
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9PAP
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6EG0
| Crystal structure of Dpr4 Ig1-Ig2 in complex with DIP-Eta Ig1-Ig3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cosmanescu, F, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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7AAL
| Crystal structure of the F-BAR domain of PSTIPIP1, G258A mutant | Descriptor: | Proline-serine-threonine phosphatase-interacting protein 1 | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | Deposit date: | 2020-09-04 | Release date: | 2022-02-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Cell.Mol.Life Sci., 79, 2022
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7AAM
| Crystal structure of the F-BAR domain of PSTIPIP1 bound to the CTH domain of the phosphatase LYP | Descriptor: | GLYCEROL, Proline-serine-threonine phosphatase-interacting protein 1, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | Deposit date: | 2020-09-04 | Release date: | 2022-02-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Cell.Mol.Life Sci., 79, 2022
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7AAN
| Crystal structure of the F-BAR domain of PSTIPIP1 | Descriptor: | Proline-serine-threonine phosphatase-interacting protein 1 | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | Deposit date: | 2020-09-04 | Release date: | 2022-02-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Cell.Mol.Life Sci., 79, 2022
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6EFY
| Crystal Structure of DIP-Alpha Ig1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein alpha, isoform A, ... | Authors: | Cosmanescu, F, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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6FF7
| human Bact spliceosome core structure | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | Authors: | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | Deposit date: | 2018-01-03 | Release date: | 2019-03-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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7AXN
| 14-3-3 sigma in complex with Pin1 binding site pS72 and covalently bound TCF521-026 | Descriptor: | 14-3-3 protein sigma, 3-chloranyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Ottmann, C. | Deposit date: | 2020-11-10 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7AYF
| 14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-110 | Descriptor: | 14-3-3 protein sigma, 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Ottmann, C. | Deposit date: | 2020-11-12 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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3WUV
| Structure basis of inactivating cell abscission with chimera peptide 2 | Descriptor: | Centrosomal protein of 55 kDa, peptide from Programmed cell death 6-interacting protein | Authors: | Kim, H.J, Matsuura, A, Lee, H.H. | Deposit date: | 2014-05-05 | Release date: | 2015-07-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells. Proc.Natl.Acad.Sci.USA, 112, 2015
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7AZ2
| 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1014 | Descriptor: | 1-[4-methyl-2-(trifluoromethyl)phenyl]-2-phenyl-imidazole, 14-3-3 protein sigma, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Ottmann, C. | Deposit date: | 2020-11-14 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.081 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7AOG
| 14-3-3 sigma in complex with Pin1 binding site pS72 | Descriptor: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2020-10-14 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7AZ1
| 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1013 | Descriptor: | 1-[4-methyl-3-(trifluoromethyl)phenyl]-2-phenyl-imidazole, 14-3-3 protein sigma, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Ottmann, C. | Deposit date: | 2020-11-14 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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6G05
| RORGT (264-518;C455S) IN COMPLEX WITH INVERSE AGONIST "CPD-2" AND RIP140 PEPTIDE AT 1.90A | Descriptor: | 2-(4-ethylsulfonylphenyl)-~{N}-[4-phenyl-5-(phenylcarbonyl)-1,3-thiazol-2-yl]ethanamide, Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1 | Authors: | Kallen, J. | Deposit date: | 2018-03-16 | Release date: | 2018-07-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimizing a Weakly Binding Fragment into a Potent ROR gamma t Inverse Agonist with Efficacy in an in Vivo Inflammation Model. J. Med. Chem., 61, 2018
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