3RS5
 
 | | H-Ras soaked in 55% dimethylformamide: 1 of 10 in MSCS set | | 分子名称: | CALCIUM ION, DIMETHYLFORMAMIDE, GTPase HRas, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RRY
 | | H-Ras crosslinked control, soaked in aqueous solution: one of 10 in MSCS set | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RS4
 | | H-Ras soaked in 60% 1,6-hexanediol: 1 of 10 in MSCS set | | 分子名称: | CALCIUM ION, GTPase HRas, HEXANE-1,6-DIOL, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RSO
 | | H-Ras soaked in 20% S,R,S-bisfuranol: 1 of 10 in MSCS set | | 分子名称: | (3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-ol, CALCIUM ION, GTPase HRas, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RAB
 | | GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PROTEIN (RAB3A) | | 著者 | Dumas, J.J, Zhu, Z, Connolly, J.L, Lambright, D.G. | | 登録日 | 1998-11-16 | | 公開日 | 1999-04-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of activation and GTP hydrolysis in Rab proteins.
Structure Fold.Des., 7, 1999
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3RS0
 | | H-Ras soaked in neat cyclopentanol: one of 10 in MSCS set | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RS2
 | | H-Ras soaked in 50% 2,2,2-trifluoroethanol: one of 10 in MSCS set | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Mattos, C, Buhrman, G, Kearney, B. | | 登録日 | 2011-05-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
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3RWM
 | | Crystal Structure of Ypt32 in Complex with GppNHp | | 分子名称: | GTP-binding protein YPT32/YPT11, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Sultana, A, Dregger, C, Jin, Y, Franklin, E, Weisman, L.S, Khan, A.R. | | 登録日 | 2011-05-09 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The activation cycle of Rab GTPase Ypt32 reveals structural determinants of effector recruitment and GDI binding.
Febs Lett., 585, 2011
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3RWO
 | | Crystal structure of YPT32 in complex with GDP | | 分子名称: | GTP-binding protein YPT32/YPT11, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Sultana, A, Jin, Y, Dregger, C, Franklin, E, Weisman, L.S, Khan, A.R. | | 登録日 | 2011-05-09 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The activation cycle of Rab GTPase Ypt32 reveals structural determinants of effector recruitment and GDI binding.
Febs Lett., 585, 2011
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3SBE
 | | Crystal structure of RAC1 P29S mutant | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-06-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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3SEA
 | | Structure of Rheb-Y35A mutant in GDP- and GMPPNP-bound forms | | 分子名称: | ACETATE ION, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Mazhab-Jafari, M.T, Marshall, C.B, Ishiyama, N, Vuk, S, Ikura, M. | | 登録日 | 2011-06-10 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis.
Structure, 20, 2012
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3SBD
 | | Crystal structure of RAC1 P29S mutant | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-06-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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3SFV
 | | Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ... | | 著者 | Yin, K, Lu, D, Zhu, D, Zhang, H, Li, B, Xu, S, Gu, L. | | 登録日 | 2011-06-14 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
Plos Pathog., 8, 2012
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3TGP
 | | Room temperature H-ras | | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Fraser, J.S, Alber, T. | | 登録日 | 2011-08-17 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.3075 Å) | | 主引用文献 | Accessing protein conformational ensembles using room-temperature X-ray crystallography.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3TH5
 | | Crystal structure of wild-type RAC1 | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-08-18 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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3TKL
 | | Crystal structure of the GTP-bound Rab1a in complex with the coiled-coil domain of LidA from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ... | | 著者 | Cheng, W, Yin, K, Lu, D, Li, B, Zhu, D, Chen, Y, Zhang, H, Xu, S, Chai, J, Gu, L. | | 登録日 | 2011-08-27 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.183 Å) | | 主引用文献 | Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state
Plos Pathog., 8, 2012
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3TVD
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8DNJ
 | | Crystal structure of human KRAS G12C covalently bound with AstraZeneca WO2020/178282A1 compound 76 | | 分子名称: | 1-[(5S,9P,12aR)-9-(2-chloro-6-hydroxyphenyl)-8-ethynyl-10-fluoro-3,4,12,12a-tetrahydro-6H-pyrazino[2,1-c][1,4]benzoxazepin-2(1H)-yl]propan-1-one, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Mohr, C. | | 登録日 | 2022-07-11 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Modeling receptor flexibility in the structure-based design of KRAS G12C inhibitors.
J.Comput.Aided Mol.Des., 36, 2022
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8DNI
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8DNK
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8EBZ
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8EM0
 | | HRAS R97V Crystal Form 1 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.109 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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8ELT
 | | HRAS R97G Crystal Form 2 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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8ELV
 | | HRAS R97I Crystal Form 2 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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8ELX
 | | HRAS R97I Crystal Form 1 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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