8SFC
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![BU of 8sfc by Molmil](/molmil-images/mine/8sfc) | Crystal structure of the engineered SsoPox variant IVA4 in alternate state | Descriptor: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | Authors: | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | Deposit date: | 2023-04-10 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase To Be Published
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5LKQ
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![BU of 5lkq by Molmil](/molmil-images/mine/5lkq) | Protease domain of RadA | Descriptor: | DNA repair protein RadA | Authors: | Rapisarda, C, Fronzes, R. | Deposit date: | 2016-07-22 | Release date: | 2017-06-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension. Nat Commun, 8, 2017
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2RM9
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![BU of 2rm9 by Molmil](/molmil-images/mine/2rm9) | Astressin2B | Descriptor: | Astressin2B | Authors: | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | Deposit date: | 2007-10-16 | Release date: | 2008-01-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
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2RME
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![BU of 2rme by Molmil](/molmil-images/mine/2rme) | Stressin | Descriptor: | Stressin | Authors: | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | Deposit date: | 2007-10-16 | Release date: | 2008-01-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
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5LVC
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![BU of 5lvc by Molmil](/molmil-images/mine/5lvc) | Aichi virus 1: empty particle | Descriptor: | VP0, VP1, VP3 | Authors: | Sabin, C, Fuzik, T, Skubnik, K, Palkova, L, Lindberg, A.M, Plevka, P. | Deposit date: | 2016-09-13 | Release date: | 2016-12-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of Aichi Virus 1 and Its Empty Particle: Clues to Kobuvirus Genome Release Mechanism. J.Virol., 90, 2016
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5LF4
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![BU of 5lf4 by Molmil](/molmil-images/mine/5lf4) | Human 20S proteasome complex with Delanzomib at 2.0 Angstrom | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | Deposit date: | 2016-06-30 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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7CDB
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![BU of 7cdb by Molmil](/molmil-images/mine/7cdb) | Structure of GABARAPL1 in complex with GABA(A) receptor gamma 2 | Descriptor: | ACETATE ION, CITRIC ACID, Gamma-aminobutyric acid receptor subunit gamma-2, ... | Authors: | Li, J, Ye, J, Zhu, R, Kong, C, Zhang, M, Wang, C. | Deposit date: | 2020-06-19 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Structural basis of GABARAP-mediated GABA A receptor trafficking and functions on GABAergic synaptic transmission. Nat Commun, 12, 2021
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5LF6
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![BU of 5lf6 by Molmil](/molmil-images/mine/5lf6) | Human 20S proteasome complex with Z-LLY-ketoaldehyde at 2.1 Angstrom | Descriptor: | CHLORIDE ION, LLY-ketoaldehyde peptide, MAGNESIUM ION, ... | Authors: | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | Deposit date: | 2016-06-30 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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7VGE
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![BU of 7vge by Molmil](/molmil-images/mine/7vge) | Structure of the PDZ deleted variant of HtrA2 protease (S306A) | Descriptor: | Serine protease HTRA2, mitochondrial | Authors: | Parui, A.L, Mishra, V, Bhaumik, P, Bose, K. | Deposit date: | 2021-09-15 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2. Structure, 30, 2022
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2RMH
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![BU of 2rmh by Molmil](/molmil-images/mine/2rmh) | Human Urocortin 3 | Descriptor: | Urocortin-3 | Authors: | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | Deposit date: | 2007-10-16 | Release date: | 2008-01-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Common and divergent structural features of a series of corticotropin releasing factor-related peptides J.Am.Chem.Soc., 129, 2007
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5LEY
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![BU of 5ley by Molmil](/molmil-images/mine/5ley) | Human 20S proteasome complex with Oprozomib at 1.9 Angstrom | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | Deposit date: | 2016-06-30 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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4C5W
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![BU of 4c5w by Molmil](/molmil-images/mine/4c5w) | Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 4-(Ethyldimethylammonio)butanoate | Descriptor: | GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, N-OXALYLGLYCINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-09-16 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
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6DME
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![BU of 6dme by Molmil](/molmil-images/mine/6dme) | ppGpp Riboswitch bound to ppGpp, thallium acetate structure | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, THALLIUM (I) ION, ... | Authors: | Peselis, A, Serganov, A. | Deposit date: | 2018-06-05 | Release date: | 2018-11-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
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5LF7
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![BU of 5lf7 by Molmil](/molmil-images/mine/5lf7) | Human 20S proteasome complex with Ixazomib at 2.0 Angstrom | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | Deposit date: | 2016-06-30 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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6DWN
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![BU of 6dwn by Molmil](/molmil-images/mine/6dwn) | Structure of Human Cytochrome P450 1A1 with Erlotinib | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Bart, A.G, Scott, E.E. | Deposit date: | 2018-06-26 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. J. Biol. Chem., 293, 2018
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8T9N
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![BU of 8t9n by Molmil](/molmil-images/mine/8t9n) | Bacillus subtilis RsgI GGG mutant | Descriptor: | Anti-sigma-I factor RsgI | Authors: | Brogan, A.P, Habib, C, Hobbs, S.J, Kranzusch, P.J, Rudner, D.Z. | Deposit date: | 2023-06-24 | Release date: | 2023-09-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis. Proc.Natl.Acad.Sci.USA, 120, 2023
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4EAI
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![BU of 4eai by Molmil](/molmil-images/mine/4eai) | Co-crystal structure of an AMPK core with AMP | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. | Deposit date: | 2012-03-22 | Release date: | 2012-06-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.285 Å) | Cite: | AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
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4EAK
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![BU of 4eak by Molmil](/molmil-images/mine/4eak) | Co-crystal structure of an AMPK core with ATP | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. | Deposit date: | 2012-03-22 | Release date: | 2012-06-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
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2UXW
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![BU of 2uxw by Molmil](/molmil-images/mine/2uxw) | Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL) | Descriptor: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, TRANS DELTA2 PALMITENOYL-COENZYMEA, ... | Authors: | Pike, A.C.W, Hozjan, V, Smee, C, Berridge, G, Burgess, N, Salah, E, Bunkoczi, G, Uppenberg, J, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U. | Deposit date: | 2007-03-30 | Release date: | 2007-05-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl) To be Published
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7NNK
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![BU of 7nnk by Molmil](/molmil-images/mine/7nnk) | Crystal structure of S116A mutant of hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 in complex with hydroxypyruvate | Descriptor: | 3-HYDROXYPYRUVIC ACID, HpcH/HpaI aldolase, MAGNESIUM ION | Authors: | Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. | Deposit date: | 2021-02-25 | Release date: | 2022-11-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
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7O7G
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![BU of 7o7g by Molmil](/molmil-images/mine/7o7g) | Crystal structure of the Shewanella oneidensis MR1 MtrC mutant H561M | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Edwards, M.J, van Wonderen, J.H, Newton-Payne, S.E, Butt, J.N, Clarke, T.A. | Deposit date: | 2021-04-13 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Nanosecond heme-to-heme electron transfer rates in a multiheme cytochrome nanowire reported by a spectrally unique His/Met-ligated heme. Proc.Natl.Acad.Sci.USA, 118, 2021
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4EAJ
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![BU of 4eaj by Molmil](/molmil-images/mine/4eaj) | Co-crystal of AMPK core with AMP soaked with ATP | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. | Deposit date: | 2012-03-22 | Release date: | 2012-06-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.609 Å) | Cite: | AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
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1KA5
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![BU of 1ka5 by Molmil](/molmil-images/mine/1ka5) | Refined Solution Structure of Histidine Containing Phosphocarrier Protein from Staphyloccocus aureus | Descriptor: | PHOSPHOCARRIER PROTEIN HPR | Authors: | Maurer, T, Meier, S, Hengstenberg, W, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE) | Deposit date: | 2001-10-31 | Release date: | 2003-06-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-resolution structure of the histidine-containing phosphocarrier protein (HPr) from Staphylococcus aureus and characterization of its interaction with the bifunctional HPr kinase/phosphorylase J.Bacteriol., 186, 2004
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7AJQ
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![BU of 7ajq by Molmil](/molmil-images/mine/7ajq) | cryo-EM structure of ExbBD from Serratia Marcescens | Descriptor: | Biopolymer transport protein ExbB, Biopolymer transport protein ExbD | Authors: | Biou, V, Adaixo, R, Coureux, P.D, Delepelaire, P, Chami, M. | Deposit date: | 2020-09-29 | Release date: | 2021-10-06 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog. Commun Biol, 5, 2022
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7NR1
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![BU of 7nr1 by Molmil](/molmil-images/mine/7nr1) | Crystal structure of holo-S116A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 | Descriptor: | HpcH/HpaI aldolase, MAGNESIUM ION | Authors: | Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. | Deposit date: | 2021-03-02 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
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