PDB: 45817 resultsInfo pagesStatus searchChemie searchBIRD

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3UXP	Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA 5'-D(P*AP*CP*TP*CP*AP*CP*AP*TP*A)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*G)-3', ... Authors: Gridley, C.L, Jaeger, J. Deposit date: 2011-12-05 Release date: 2012-12-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.723 Å) Cite: Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta. Biochemistry, 52, 2013
2BPF	STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R, Kumar, A, Wilson, S.H, Kraut, J. Deposit date: 1994-05-19 Release date: 1994-12-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science, 264, 1994
4K4G	Ternary crystal structures of human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND L-DCTP. Descriptor: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ACETATE ION, CACODYLATE ION, ... Authors: Vyas, R, Suo, Z. Deposit date: 2013-04-12 Release date: 2014-07-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111, 2014
4K4I	Ternary crystal structures of a human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)FTC-TP. Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ... Authors: Vyas, R, Suo, Z. Deposit date: 2013-04-12 Release date: 2014-07-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111, 2014
6UI2	Structure of human DNA polymerase eta complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(FMG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2019-09-30 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase eta. Molecules, 24, 2019
2R9L	Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DAP*DCP*DGP*DCP*DA)-3'), ... Authors: Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J. Deposit date: 2007-09-13 Release date: 2008-01-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of a NHEJ polymerase-mediated DNA synaptic complex Science, 318, 2007
4K4H	Ternary crystal structures of a human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)3TC-TP. Descriptor: ACETATE ION, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... Authors: Vyas, R, Suo, Z. Deposit date: 2013-04-12 Release date: 2014-07-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111, 2014
4LEY	Structure of mouse cGAS bound to 18 bp DNA Descriptor: 18 bp dsDNA, Cyclic GMP-AMP synthase, ZINC ION Authors: Li, P. Deposit date: 2013-06-26 Release date: 2013-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization. Immunity, 39, 2013
3WPD	Crystal structure of horse TLR9 in complex with inhibitory DNA4084 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*G)-3'), ... Authors: Ohto, U, Tanji, H, Shimizu, T. Deposit date: 2014-01-11 Release date: 2015-02-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 Nature, 520, 2015
2IS2	Crystal structure of UvrD-DNA binary complex Descriptor: 33-MER, DNA helicase II, FORMIC ACID, ... Authors: Yang, W, Lee, J.Y. Deposit date: 2006-10-16 Release date: 2007-01-09 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell(Cambridge,Mass.), 127, 2006
2IS1	Crystal structure of UvrD-DNA-SO4 complex Descriptor: 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*TP*TP*TP*TP*T)-3', DNA helicase II, ... Authors: Yang, W, Lee, J.Y. Deposit date: 2006-10-16 Release date: 2007-01-09 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell(Cambridge,Mass.), 127, 2006
3WPG	Crystal structure of mouse TLR9 in complex with inhibitory DNA4084 (form 1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*GP*AP*A)-3'), SULFATE ION, ... Authors: Ohto, U, Shimizu, T. Deposit date: 2014-01-11 Release date: 2015-02-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.246 Å) Cite: Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 Nature, 520, 2015
1F69	CRYSTAL STRUCTURE OF THE B-DNA HEXAMER GGCGCC WITH COBALT HEXAMINE Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*GP*CP*C)-3'), MAGNESIUM ION Authors: Vargason, J.M, Eichman, B.F, Ho, P.S. Deposit date: 2000-06-20 Release date: 2000-08-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The extended and eccentric E-DNA structure induced by cytosine methylation or bromination. Nat.Struct.Biol., 7, 2000
2IS6	Crystal structure of UvrD-DNA-ADPMgF3 ternary complex Descriptor: 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*GP*TP*TP*AP*T)-3', ADENOSINE-5'-DIPHOSPHATE, DNA helicase II, ... Authors: Yang, W, Lee, J.Y. Deposit date: 2006-10-16 Release date: 2007-01-09 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell(Cambridge,Mass.), 127, 2006
3EYI	The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA Descriptor: 5'-TCGCGCG-3', Z-DNA-binding protein 1 Authors: Ha, S.C, Kim, K.K. Deposit date: 2008-10-21 Release date: 2009-01-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA. Proc.Natl.Acad.Sci.USA, 105, 2008
1OUP	Crystal structure of the periplasmic endonuclease Vvn complexed with octamer double stranded DNA Descriptor: 5'-D(*GP*CP*GP*AP*TP*C)-3', 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', 5'-D(P*GP*C)-3', ... Authors: Yuan, H.S, Li, C.-L. Deposit date: 2003-03-25 Release date: 2003-08-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site. Embo J., 22, 2003
3WPH	Crystal structure of mouse TLR9 in complex with inhibitory DNA4084 (form 2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*GP*AP*A)-3'), SULFATE ION, ... Authors: Ohto, U, Shimizu, T. Deposit date: 2014-01-11 Release date: 2015-02-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.327 Å) Cite: Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 Nature, 520, 2015
2IS4	Crystal structure of UvrD-DNA-ADPNP ternary complex Descriptor: 25-MER, DNA helicase II, MAGNESIUM ION, ... Authors: Yang, W, Lee, J.Y. Deposit date: 2006-10-16 Release date: 2007-01-09 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell(Cambridge,Mass.), 127, 2006
6S2E	Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon Descriptor: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... Authors: Grabarczyk, D.B, Song, B. Deposit date: 2019-06-20 Release date: 2020-07-08 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
4IRB	Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4 Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ... Authors: Schormann, N, Zhukovskaya, N, Sartmatova, D, Nuth, M, Ricciardi, R.P, Chattopadhyay, D. Deposit date: 2013-01-14 Release date: 2014-02-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase To be Published
8A5Q	Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... Authors: Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. Deposit date: 2022-06-15 Release date: 2022-12-14 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
8A5P	Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... Authors: Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. Deposit date: 2022-06-15 Release date: 2022-12-14 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
4K8Z	KOD Polymerase in binary complex with dsDNA Descriptor: 1,2-ETHANEDIOL, COBALT HEXAMMINE(III), DNA (5'-D(*AP*AP*AP*TP*TP*CP*GP*CP*AP*GP*TP*TP*CP*GP*CP*G)-3'), ... Authors: Bergen, K, Betz, K, Welte, W, Diederichs, K, Marx, A. Deposit date: 2013-04-19 Release date: 2013-06-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex Chembiochem, 14, 2013
227D	A CRYSTALLOGRAPHIC AND SPECTROSCOPIC STUDY OF THE COMPLEX BETWEEN D(CGCGAATTCGCG)2 AND 2,5-BIS(4-GUANYLPHENYL)FURAN, AN ANALOGUE OF BERENIL. STRUCTURAL ORIGINS OF ENHANCED DNA-BINDING AFFINITY Descriptor: 2,5-BIS(4-GUANYLPHENYL)FURAN, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') Authors: Laughton, C.A, Tanious, F, Nunn, C.M, Boykin, D.W, Wilson, W.D, Neidle, S. Deposit date: 1995-08-08 Release date: 1995-11-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity. Biochemistry, 35, 1996
8EAK	SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 2 Descriptor: 46-mer DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022

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