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2OPG
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The crystal structure of the 10th PDZ domain of MPDZ
Descriptor: Multiple PDZ domain protein, SODIUM ION
Authors:Gileadi, C, Phillips, C, Elkins, J, Papagrigoriou, E, Ugochukwu, E, Gorrec, F, Savitsky, P, Umeano, C, Berridge, G, Gileadi, O, Salah, E, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-01-29
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 10th PDZ domain of MPDZ
To be Published
1YBO
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BU of 1ybo by Molmil
Crystal structure of the PDZ tandem of human syntenin with syndecan peptide
Descriptor: Syndecan-4, Syntenin 1
Authors:Grembecka, J, Cooper, D.R, Cierpicki, T, Kang, B.S, Devedjiev, Y, Derewenda, Z.
Deposit date:2004-12-21
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
2OQS
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BU of 2oqs by Molmil
Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide
Descriptor: C-terminal HPV-18 E6 peptide, Disks large homolog 1
Authors:Liu, Y, Baleja, J.D, Henry, G.D, Hegde, R.S.
Deposit date:2007-02-01
Release date:2007-09-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.
Biochemistry, 46, 2007
2OSG
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BU of 2osg by Molmil
Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2
Descriptor: Tight junction protein ZO-2
Authors:Wu, J.W, Yang, Y.S, Zhang, J.H, Ji, P, Wu, J.H, Shi, Y.Y.
Deposit date:2007-02-05
Release date:2007-09-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins
J.Biol.Chem., 282, 2007
1Z86
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Solution structure of the PDZ domain of alpha-syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
1XZ9
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BU of 1xz9 by Molmil
Structure of AF-6 PDZ domain
Descriptor: Afadin
Authors:Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H.
Deposit date:2004-11-12
Release date:2005-11-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angew.Chem.Int.Ed.Engl., 45, 2006
2L4S
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BU of 2l4s by Molmil
Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L
Descriptor: Tax1-binding protein 3
Authors:Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S.
Deposit date:2010-10-13
Release date:2011-04-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
2PKT
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Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Uppenberg, J, Gileadi, C, Elkins, J, Bray, J, Burgess-Brown, N, Salah, E, Gileadi, O, Bunkoczi, G, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-04-18
Release date:2007-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
1ZOK
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PDZ1 Domain Of Synapse Associated Protein 97
Descriptor: Presynaptic protein SAP97
Authors:Wang, L, Piserchio, A, Mierke, D.F.
Deposit date:2005-05-13
Release date:2005-06-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.
J.Biol.Chem., 280, 2005
2M0U
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BU of 2m0u by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1
Descriptor: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2MHO
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BU of 2mho by Molmil
Solution State Structure PSD-95 PDZ1 with 5HT2C Receptor peptide
Descriptor: Disks large homolog 4, peptide from 5-hydroxytryptamine receptor 2C
Authors:Dorr, L.A, Phelan, M.M, Lian, L.
Deposit date:2013-11-29
Release date:2014-03-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Interactions of the 5-Hydroxytryptamine Receptor 2a and 2c Variants with the PSD-MAGUK proteins, PSD-95 and SAP997
To be Published
1ZUB
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Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide
Descriptor: ELKS1b, Regulating synaptic membrane exocytosis protein 1
Authors:Lu, J, Li, H, Wang, Y, Sudhof, T.C, Rizo, J.
Deposit date:2005-05-30
Release date:2005-08-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide
J.Mol.Biol., 352, 2005
2PKU
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Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
Descriptor: PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE)
Authors:Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M.
Deposit date:2007-04-18
Release date:2007-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Embo J., 26, 2007
2Q3G
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BU of 2q3g by Molmil
Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PDZ and LIM domain protein 7
Authors:Gileadi, C, Papagrigoriou, E, Elkins, J, Burgess-Brown, N, Salah, E, Gileadi, O, Umeano, C, Bunkoczi, G, von Delft, F, Uppenberg, J, Pike, A.C.W, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-06-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2M0Z
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cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13
Authors:Walser, R, Zerbe, O, Hamm, P.
Deposit date:2012-11-09
Release date:2013-07-03
Last modified:2013-08-07
Method:SOLUTION NMR
Cite:Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
2PNT
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BU of 2pnt by Molmil
Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1
Descriptor: CHLORIDE ION, General receptor for phosphoinositides 1-associated scaffold protein
Authors:Elkins, J, Papagrigoriou, E, Cooper, C, Gileadi, C, Uppenberg, J, Bray, J, von Delft, F, Pike, A.C.W, Ugochukwu, E, Umeano, C, Gileadi, O, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-04-25
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2F0A
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BU of 2f0a by Molmil
Crystal Structure of Monomeric Uncomplexed form of Xenopus dishevelled PDZ domain
Descriptor: COBALT (II) ION, SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
Authors:Friedland, N, Hung, L.-W, Cheyette, B, Moon, R.T, Earnest, T.N.
Deposit date:2005-11-12
Release date:2005-11-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational flexibility in the PDZ domain of Dishevelled induced by target binding
TO BE PUBLISHED
2FNE
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BU of 2fne by Molmil
The crystal structure of the 13th PDZ domain of MPDZ
Descriptor: Multiple PDZ domain protein
Authors:Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FCF
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BU of 2fcf by Molmil
The crystal structure of the 7th PDZ domain of MPDZ (MUPP-1)
Descriptor: Multiple PDZ domain protein
Authors:Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2005-12-12
Release date:2006-01-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2I1N
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BU of 2i1n by Molmil
Crystal structure of the 1st PDZ domain of Human DLG3
Descriptor: Discs, large homolog 3, SODIUM ION
Authors:Turnbull, A.P, Phillips, C, Bunkoczi, G, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Gorrec, F, Umeano, C, Elkins, J, Berridge, G, Savitsky, P, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-08-14
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2I04
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BU of 2i04 by Molmil
X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6
Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, SULFATE ION, ...
Authors:Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M.
Deposit date:2006-08-09
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
2I0L
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BU of 2i0l by Molmil
X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6.
Descriptor: Disks large homolog 1, peptide E6
Authors:Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M.
Deposit date:2006-08-10
Release date:2007-02-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
2I0I
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BU of 2i0i by Molmil
X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6
Descriptor: Disks large homolog 1, peptide E6
Authors:Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M.
Deposit date:2006-08-10
Release date:2007-02-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
2HE4
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The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif
Descriptor: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Authors:Papagrigoriou, E, Elkins, J.M, Berridge, G, Gileady, O, Colebrook, S, Gileadi, C, Salah, E, Savitsky, P, Pantic, N, Gorrec, F, Bunkoczi, G, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2IWQ
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7th PDZ domain of Multiple PDZ Domain Protein MPDZ
Descriptor: MULTIPLE PDZ DOMAIN PROTEIN
Authors:Elkins, J.M, Berridge, G, Savitsky, P, Smee, C.E.A, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A.
Deposit date:2006-07-03
Release date:2006-07-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007

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