8CU1
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![BU of 8cu1 by Molmil](/molmil-images/mine/8cu1) | Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 500ns, with eightfold extrapolation of structure factor differences | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | Authors: | Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D. | Deposit date: | 2022-05-16 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Direct visualization of electric field-stimulated ion conduction in a potassium channel To Be Published
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8CU3
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![BU of 8cu3 by Molmil](/molmil-images/mine/8cu3) | Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 200ns, with eightfold extrapolation of structure factor differences | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | Authors: | Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D. | Deposit date: | 2022-05-16 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Direct visualization of electric field-stimulated ion conduction in a potassium channel To Be Published
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8CU2
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![BU of 8cu2 by Molmil](/molmil-images/mine/8cu2) | Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 100ns, with eightfold extrapolation of structure factor differences | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | Authors: | Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D. | Deposit date: | 2022-05-16 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Direct visualization of electric field-stimulated ion conduction in a potassium channel To Be Published
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6V22
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![BU of 6v22 by Molmil](/molmil-images/mine/6v22) | Cryo-EM structure of Ca2+-bound hsSlo1-beta4 channel complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tao, X, MacKinnon, R. | Deposit date: | 2019-11-22 | Release date: | 2019-12-25 | Last modified: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4. Elife, 8, 2019
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1BUN
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![BU of 1bun by Molmil](/molmil-images/mine/1bun) | STRUCTURE OF BETA2-BUNGAROTOXIN: POTASSIUM CHANNEL BINDING BY KUNITZ MODULES AND TARGETED PHOSPHOLIPASE ACTION | Descriptor: | BETA2-BUNGAROTOXIN, SODIUM ION | Authors: | Kwong, P.D, Mcdonald, N.Q, Sigler, P.B, Hendrickson, W.A. | Deposit date: | 1995-10-15 | Release date: | 1996-04-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of beta 2-bungarotoxin: potassium channel binding by Kunitz modules and targeted phospholipase action. Structure, 3, 1995
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7LJ5
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![BU of 7lj5 by Molmil](/molmil-images/mine/7lj5) | |
7LJB
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7LJ4
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![BU of 7lj4 by Molmil](/molmil-images/mine/7lj4) | |
2HEO
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![BU of 2heo by Molmil](/molmil-images/mine/2heo) | General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers. | Descriptor: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 | Authors: | Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P. | Deposit date: | 2006-06-21 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers. J.Am.Chem.Soc., 128, 2006
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2K1E
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![BU of 2k1e by Molmil](/molmil-images/mine/2k1e) | NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA | Descriptor: | water soluble analogue of potassium channel, KcsA | Authors: | Ma, D, Xu, Y, Tillman, T, Tang, P, Meirovitch, E, Eckenhoff, R, Carnini, A. | Deposit date: | 2008-02-29 | Release date: | 2008-11-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1B4G
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![BU of 1b4g by Molmil](/molmil-images/mine/1b4g) | CONTROL OF K+ CHANNEL GATING BY PROTEIN PHOSPHORYLATION: STRUCTURAL SWITCHES OF THE INACTIVATION GATE, NMR, 22 STRUCTURES | Descriptor: | POTASSIUM CHANNEL | Authors: | Antz, C, Bauer, T, Kalbacher, H, Frank, R, Covarrubias, M, Kalbitzer, H.R, Ruppersberg, J.P, Baukrowitz, T, Fakler, B. | Deposit date: | 1998-12-22 | Release date: | 1999-04-27 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate. Nat.Struct.Biol., 6, 1999
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1B4I
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![BU of 1b4i by Molmil](/molmil-images/mine/1b4i) | Control of K+ Channel Gating by protein phosphorylation: structural switches of the inactivation gate, NMR, 22 structures | Descriptor: | POTASSIUM CHANNEL | Authors: | Antz, C, Bauer, T, Kalbacher, H, Frank, R, Covarrubias, M, Kalbitzer, H.R, Ruppersberg, J.P, Baukrowitz, T, Fakler, B. | Deposit date: | 1998-12-22 | Release date: | 1999-04-27 | Last modified: | 2022-03-23 | Method: | SOLUTION NMR | Cite: | Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate. Nat.Struct.Biol., 6, 1999
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5VA1
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![BU of 5va1 by Molmil](/molmil-images/mine/5va1) | |
7PQT
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![BU of 7pqt by Molmil](/molmil-images/mine/7pqt) | Apo human Kv3.1 cryo-EM structure | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | Authors: | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | Deposit date: | 2021-09-20 | Release date: | 2022-08-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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6WLV
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![BU of 6wlv by Molmil](/molmil-images/mine/6wlv) | TASK2 in MSP1D1 lipid nanodisc at pH 6.5 | Descriptor: | POTASSIUM ION, Potassium channel TASK2 | Authors: | Li, B, Brohawn, S.G. | Deposit date: | 2020-04-20 | Release date: | 2020-07-15 | Last modified: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural basis for pH gating of the two-pore domain K + channel TASK2. Nature, 586, 2020
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6WM0
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![BU of 6wm0 by Molmil](/molmil-images/mine/6wm0) | TASK2 in MSP1D1 lipid nanodisc at pH 8.5 | Descriptor: | POTASSIUM ION, Potassium channel TASK2 | Authors: | Li, B, Brohawn, S.G. | Deposit date: | 2020-04-20 | Release date: | 2020-07-15 | Last modified: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural basis for pH gating of the two-pore domain K + channel TASK2. Nature, 586, 2020
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7LGV
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7UK5
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4LLO
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2OVC
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7UKD
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![BU of 7ukd by Molmil](/molmil-images/mine/7ukd) | Human Kv4.2-KChIP2 channel complex in an inactivated state, class 2, transmembrane region | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2 | Authors: | Zhao, H, Dai, Y, Lee, C.H. | Deposit date: | 2022-04-01 | Release date: | 2022-06-29 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes. Mol.Cell, 82, 2022
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7UKC
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![BU of 7ukc by Molmil](/molmil-images/mine/7ukc) | Human Kv4.2-KChIP2 channel complex in an inactivated state, class 1, transmembrane region | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2 | Authors: | Zhao, H, Dai, Y, Lee, C.H. | Deposit date: | 2022-04-01 | Release date: | 2022-06-29 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes. Mol.Cell, 82, 2022
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7UKE
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1WPD
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![BU of 1wpd by Molmil](/molmil-images/mine/1wpd) | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins | Descriptor: | Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3 | Authors: | Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M. | Deposit date: | 2004-09-01 | Release date: | 2004-10-19 | Last modified: | 2019-12-18 | Method: | SOLUTION NMR | Cite: | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins J.Biol.Chem., 279, 2004
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1F6G
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![BU of 1f6g by Molmil](/molmil-images/mine/1f6g) | POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD | Descriptor: | VOLTAGE-GATED POTASSIUM CHANNEL | Authors: | Cortes, D.M, Perozo, E. | Deposit date: | 2000-06-21 | Release date: | 2001-02-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J.Gen.Physiol., 117, 2001
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