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7VAU
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BU of 7vau by Molmil
V1EG of V/A-ATPase from Thermus thermophilus at low ATP concentration, state2-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7VAY
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BU of 7vay by Molmil
V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
2PT1
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BU of 2pt1 by Molmil
FutA1 Synechocystis PCC 6803
Descriptor: Iron transport protein, SULFATE ION
Authors:Koropatkin, N.M, Randich, A.M, Bhattachryya-Pakrasi, M, Pakrasi, H.B, Smith, T.J.
Deposit date:2007-05-07
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the iron-binding protein, FutA1, from Synechocystis 6803.
J.Biol.Chem., 282, 2007
1N0V
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BU of 1n0v by Molmil
Crystal structure of elongation factor 2
Descriptor: Elongation factor 2
Authors:Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R.
Deposit date:2002-10-15
Release date:2002-11-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat.Struct.Biol., 10, 2003
3ZO3
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BU of 3zo3 by Molmil
The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
Descriptor: 6-(2,9-DIAZASPIRO[5.5]UNDECAN-2-YL)-9H-PURINE, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ...
Authors:Allen, C.E, Chow, C.L, Caldwell, J.J, Westwood, I.M, van Montfort, R.L, Collins, I.
Deposit date:2013-02-20
Release date:2013-03-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases.
Bioorg. Med. Chem., 21, 2013
6J5L
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BU of 6j5l by Molmil
Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
Descriptor: High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide
Authors:Kensuke, A, Kazutaka, I.
Deposit date:2019-01-11
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain.
Bioorg.Med.Chem.Lett., 29, 2019
7Z4C
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BU of 7z4c by Molmil
SpCas9 bound to 6 nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 6 nucleotide complementary DNA substrate, Target strand of 6 nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4G
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BU of 7z4g by Molmil
SpCas9 bound to 12-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 12-nucleotide complementary DNA substrate, Target strand of 12-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4H
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BU of 7z4h by Molmil
SpCas9 bound to 14-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 14-nucleotide complementary DNA substrate, Target strand of 14-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4K
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BU of 7z4k by Molmil
SpCas9 bound to 10-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10-nucleotide complementary DNA substrate, Target strand of 10-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-04
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
2BBD
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BU of 2bbd by Molmil
Crystal Structure of the STIV MCP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, coat protein
Authors:Khayat, R.
Deposit date:2005-10-17
Release date:2005-12-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2VL0
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BU of 2vl0 by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC)
Descriptor: Cys-loop ligand-gated ion channel
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-01-07
Release date:2008-03-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:X-Ray Structure of a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nature, 452, 2008
1N0U
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BU of 1n0u by Molmil
Crystal structure of yeast elongation factor 2 in complex with sordarin
Descriptor: Elongation factor 2, [1R-(1.ALPHA.,3A.BETA.,4.BETA.,4A.BETA.,7.BETA.,7A.ALPHA.,8A.BETA.)]8A-[(6-DEOXY-4-O-METHYL-BETA-D-ALTROPYRANOSYLOXY)METHYL]-4-FORMYL-4,4A,5,6,7,7A,8,8A-OCTAHYDRO-7-METHYL-3-(1-METHYLETHYL)-1,4-METHANO-S-INDACENE-3A(1H)-CARBOXYLIC ACID
Authors:Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R.
Deposit date:2002-10-15
Release date:2003-02-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat. Struct. Biol., 10, 2003
1GML
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BU of 1gml by Molmil
crystal structure of the mouse CCT gamma apical domain (triclinic)
Descriptor: GLYCEROL, T-COMPLEX PROTEIN 1 SUBUNIT GAMMA
Authors:Pappenberger, G, Wilsher, J.A, Roe, S.M, Willison, K.R, Pearl, L.H.
Deposit date:2001-09-17
Release date:2002-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Cct Gamma Apical Domain:: Implications for Substrate Binding to the Eukaryotic Cytosolic Chaperonin
J.Mol.Biol., 318, 2002
1GN1
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BU of 1gn1 by Molmil
crystal structure of the mouse CCT gamma apical domain (monoclinic)
Descriptor: CALCIUM ION, CCT-GAMMA
Authors:Pappenberger, G, Wilsher, J.A, Roe, S.M, Willison, K.R, Pearl, L.H.
Deposit date:2001-10-01
Release date:2002-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Cct Gamma Apical Domain:: Implications for Substrate Binding to the Eukaryotic Cytosolic Chaperonin
J.Mol.Biol., 318, 2002
2VCO
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BU of 2vco by Molmil
Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope
Descriptor: NICKEL (II) ION, PROTEIN FIMH, SULFATE ION, ...
Authors:Wellens, A, Garofalo, C, Nguyen, H, Wyns, L, De Greve, H, Hultgren, S.J, Bouckaert, J.
Deposit date:2007-09-26
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the Fimh-Oligomannose-3 Complex.
Plos One, 3, 2008
4MTA
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BU of 4mta by Molmil
Crystal structure of Pim-1 kinase domain in complex with 2-methyl-5-phenylfuran-3-carboxylic acid
Descriptor: 2-methyl-5-phenylfuran-3-carboxylic acid, GLYCEROL, Serine/threonine-protein kinase pim-1
Authors:Scheufler, C, Be, C.
Deposit date:2013-09-19
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies.
J Biomol Screen, 20, 2015
2PT2
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BU of 2pt2 by Molmil
Structure of FutA1 with Iron(II)
Descriptor: 1,2-ETHANEDIOL, FE (II) ION, Iron transport protein, ...
Authors:Koropatkin, N.M, Randich, A.M, Bhattachryya-Pakrasi, M, Pakrasi, H.B, Smith, T.J.
Deposit date:2007-05-07
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the iron-binding protein, FutA1, from Synechocystis 6803.
J.Biol.Chem., 282, 2007
5VWT
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BU of 5vwt by Molmil
Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADPH
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2017-05-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.
J. Am. Chem. Soc., 134, 2012
2YKS
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BU of 2yks by Molmil
PENTAMERIC LIGAND GATED ION CHANNEL ELIC MUTANT F246A
Descriptor: CYS-LOOP LIGAND-GATED ION CHANNEL
Authors:Zimmermann, I, Dutzler, R.
Deposit date:2011-05-30
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel Elic.
Plos Biol., 9, 2011
4NT1
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BU of 4nt1 by Molmil
Crystal structure of apo-form of Arabidopsis ACD11 (accelerated-cell-death 11) at 1.8 Angstrom resolution
Descriptor: SODIUM ION, accelerated-cell-death 11
Authors:Simanshu, D.K, Brown, R.E, Patel, D.J.
Deposit date:2013-11-29
Release date:2014-02-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4M3W
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BU of 4m3w by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-4 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
2HW4
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BU of 2hw4 by Molmil
Crystal structure of human phosphohistidine phosphatase
Descriptor: 14 kDa phosphohistidine phosphatase, FORMIC ACID
Authors:Busam, R.D, Thorsell, A.G, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Stenmark, P, Sundstrom, M, Uppenberg, J, Van Den Berg, S, Weigelt, J, Persson, C, Hallberg, B.M, Structural Genomics Consortium (SGC)
Deposit date:2006-07-31
Release date:2006-08-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:First structure of a eukaryotic phosphohistidine phosphatase
J.Biol.Chem., 281, 2006
6U5S
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BU of 6u5s by Molmil
NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in pseudo-symmetric global conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Nakagawa, T.
Deposit date:2019-08-28
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6HMW
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BU of 6hmw by Molmil
Cholera toxin classical B-pentamer in complex with fucose
Descriptor: BICINE, CALCIUM ION, Cholera enterotoxin B-subunit, ...
Authors:Krengel, U, Heim, J.B.
Deposit date:2018-09-13
Release date:2019-08-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.
Sci Rep, 9, 2019

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