4MTA

Crystal structure of Pim-1 kinase domain in complex with 2-methyl-5-phenylfuran-3-carboxylic acid

Summary for 4MTA

Entry DOI	10.2210/pdb4mta/pdb
Descriptor	Serine/threonine-protein kinase pim-1, 2-methyl-5-phenylfuran-3-carboxylic acid, GLYCEROL, ... (4 entities in total)
Functional Keywords	serine/threonine-protein kinase, atp-binding, transferase
Biological source	Homo sapiens (human)
Cellular location	Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
Total number of polymer chains	1
Total formula weight	33140.58
Authors	Scheufler, C.,Be, C. (deposition date: 2013-09-19, release date: 2015-01-14, Last modification date: 2023-09-20)
Primary citation	Kutchukian, P.S.,Wassermann, A.M.,Lindvall, M.K.,Wright, S.K.,Ottl, J.,Jacob, J.,Scheufler, C.,Marzinzik, A.,Brooijmans, N.,Glick, M. Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies. J Biomol Screen, 20:588-596, 2015 Cited by PubMed: 25550355 DOI: 10.1177/1087057114565080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation