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3LET
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BU of 3let by Molmil
Crystal Structure of Fic domain containing AMPylator, VopS
Descriptor: Adenosine monophosphate-protein transferase vopS
Authors:Luong, P.H, Kinch, L.N, Brautigam, C.A, Grishin, N.V, Tomchick, D.R, Orth, K.
Deposit date:2010-01-15
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation
To be Published
5FTI
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BU of 5fti by Molmil
Crystal structure of the GluA2 K738M-T744K LBD in complex with glutamate (lithium form)
Descriptor: GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, GLYCEROL, ...
Authors:Nayeem, N, Green, T.
Deposit date:2016-01-13
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Distinct Structural Pathways Coordinate the Activation of Ampa Receptor-Auxiliary Subunit Complexes.
Neuron, 89, 2016
2AL4
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614.
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE, Glutamate receptor 2, ...
Authors:Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M.
Deposit date:2005-08-04
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
4XSQ
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BU of 4xsq by Molmil
Structure of a variable lymphocyte receptor-like protein Bf66946 from Branchiostoma floridae
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, variable lymphocyte receptor-like protein Bf66946
Authors:Cao, D.D, Cheng, W, Jiang, Y.L, Wang, W.J, Li, Q, Chen, Y, Zhou, C.Z.
Deposit date:2015-01-22
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of a variable lymphocyte receptor-like protein from the amphioxus Branchiostoma floridae.
Sci Rep, 6, 2016
6FFQ
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BU of 6ffq by Molmil
Solution NMR structure of CBM64 from S.thermophila
Descriptor: Glycosyl hydrolase family 5 cellulase CBM64
Authors:Heikkinen, H.A, Iwai, H.
Deposit date:2018-01-09
Release date:2019-01-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:NMR Structure Determinations of Small Proteins Using only One Fractionally 20% 13 C- and Uniformly 100% 15 N-Labeled Sample.
Molecules, 26, 2021
6FFU
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BU of 6ffu by Molmil
Solution NMR structure of CBM64 from S.thermophila using 20% 13C, 100% 15N
Descriptor: Glycosyl hydrolase family 5 cellulase CBM64
Authors:Heikkinen, H.A, Iwai, H.
Deposit date:2018-01-09
Release date:2019-01-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:NMR Structure Determinations of Small Proteins Using only One Fractionally 20% 13 C- and Uniformly 100% 15 N-Labeled Sample.
Molecules, 26, 2021
6FQK
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BU of 6fqk by Molmil
GluA2(flop) S729C ligand binding core dimer bound to ZK200775 at 1.98 Angstrom resolution
Descriptor: Glutamate receptor 2,Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
Deposit date:2018-02-14
Release date:2019-03-13
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.98010445 Å)
Cite:Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FQJ
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GluA2(flop) G724C ligand binding core dimer bound to ZK200775 at 2.50 Angstrom resolution
Descriptor: Glutamate receptor 2,Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
Deposit date:2018-02-14
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.500017 Å)
Cite:Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
3LSF
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BU of 3lsf by Molmil
Piracetam bound to the ligand binding domain of GluA2
Descriptor: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
Authors:Ahmed, A.H, Ptak, C.P, Oswald, R.E.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3LSL
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BU of 3lsl by Molmil
Piracetam bound to the ligand binding domain of GluA2 (flop form)
Descriptor: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
Authors:Ahmed, A.H, Oswald, R.E.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.122 Å)
Cite:Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
3M3F
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BU of 3m3f by Molmil
PEPA bound to the ligand binding domain of GluA3 (flop form)
Descriptor: 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, GLUTAMIC ACID, Glutamate receptor 3, ...
Authors:Ahmed, A.H, Ptak, C.P, Oswald, R.E.
Deposit date:2010-03-09
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
Biochemistry, 49, 2010
1YQ9
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BU of 1yq9 by Molmil
Structure of the unready oxidized form of [NiFe] hydrogenase
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ...
Authors:Volbeda, A, Martin, L, Cavazza, C, Matho, M, Faber, B.W, Roseboom, W, Albracht, S.P, Garcin, E, Rousset, M, Fontecilla-Camps, J.C.
Deposit date:2005-02-01
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural differences between the ready and unready oxidized states of [NiFe] hydrogenases.
J.Biol.Inorg.Chem., 10, 2005
6FQH
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BU of 6fqh by Molmil
GluA2(flop) S729C ligand binding core dimer bound to NBQX at 1.76 Angstrom resolution
Descriptor: 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2,Glutamate receptor 2
Authors:Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
Deposit date:2018-02-14
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75940013 Å)
Cite:Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
5VHZ
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BU of 5vhz by Molmil
GluA2-2xGSG1L bound to L-Quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2,Germ cell-specific gene 1-like protein
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHW
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BU of 5vhw by Molmil
GluA2-0xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHY
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BU of 5vhy by Molmil
GluA2-2xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
4PPH
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BU of 4pph by Molmil
Crystal structure of conglutin gamma, a unique basic 7S globulin from lupine seeds
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Czubinski, J, Barciszewski, J, Gilski, M, Lampart-Szczapa, E, Jaskolski, M.
Deposit date:2014-02-27
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Structure of gamma-conglutin: insight into the quaternary structure of 7S basic globulins from legumes.
Acta Crystallogr.,Sect.D, 71, 2015
3B6T
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BU of 3b6t by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Cho, Y, Lolis, E, Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
2AL5
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BU of 2al5 by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam
Descriptor: 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2
Authors:Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M.
Deposit date:2005-08-04
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
3B7D
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BU of 3b7d by Molmil
Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A resolution
Descriptor: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2
Authors:Hays, F.A, Center for Structures of Membrane Proteins (CSMP)
Deposit date:2007-10-30
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.
Science, 318, 2007
4V11
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BU of 4v11 by Molmil
Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84
Descriptor: CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ...
Authors:Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R.
Deposit date:2014-09-22
Release date:2015-02-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
6ODJ
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BU of 6odj by Molmil
PolyAla Model of the PRC from the Type 4 Secretion System of H. pylori
Descriptor: PolyAla Model of PRC from H.pylori
Authors:Chung, J.M, Sheedlo, M.J, Campbell, A, Sawhney, N, Frick-Cheng, A.E, Lacy, D.B, Cover, T.L, Ohi, M.D.
Deposit date:2019-03-26
Release date:2019-07-03
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Helicobacter pylori Cag type IV secretion system.
Elife, 8, 2019
6OEG
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BU of 6oeg by Molmil
Structure of CagX from a cryo-EM reconstruction of a T4SS
Descriptor: Type IV secretion system apparatus protein CagX
Authors:Chung, J.M, Sheedlo, M.J, Campbell, A, Sawhney, N, Frick-Cheng, A.E, Lacy, D.B, Cover, T.L, Ohi, M.D.
Deposit date:2019-03-27
Release date:2019-07-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the Helicobacter pylori Cag type IV secretion system.
Elife, 8, 2019
2CHV
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BU of 2chv by Molmil
Replication Factor C ADPNP complex
Descriptor: REPLICATION FACTOR C SMALL SUBUNIT
Authors:Seybert, A, Singleton, M.R, Cook, N, Hall, D.R, Wigley, D.B.
Deposit date:2006-03-16
Release date:2006-06-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (4 Å)
Cite:Communication between Subunits within an Archaeal Clamp-Loader Complex.
Embo J., 25, 2006
6OEH
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BU of 6oeh by Molmil
PolyAla Model of OMCC I-Layer
Descriptor: PolyAla Model of OMCC I-Layer
Authors:Chung, J.M, Sheedlo, M.J, Campbell, A, Sawhney, N, Frick-Cheng, A.E, Lacy, D.B, Cover, T.L, Ohi, M.D.
Deposit date:2019-03-27
Release date:2019-07-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the Helicobacter pylori Cag type IV secretion system.
Elife, 8, 2019

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