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3P8R
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BU of 3p8r by Molmil
CRYSTAL STRUCTURE OF POLYPRENYL SYNTHASE FROM Vibrio cholerae
Descriptor: Geranyltranstransferase
Authors:Patskovsky, Y, Toro, R, Dickey, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-10-14
Release date:2010-10-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1ILT
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BU of 1ilt by Molmil
X-RAY STRUCTURE OF INTERLEUKIN-1 RECEPTOR ANTAGONIST AT 2.0 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-1 RECEPTOR ANTAGONIST
Authors:Brandhuber, B.J, Vigers, G.P.A.
Deposit date:1994-03-09
Release date:1995-04-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution.
J.Biol.Chem., 269, 1994
3P9W
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BU of 3p9w by Molmil
Crystal structure of an engineered human autonomous VH Domain in complex with VEGF
Descriptor: Vascular endothelial growth factor A, human VEGF
Authors:Ma, X, Wiesmann, C.
Deposit date:2010-10-18
Release date:2012-04-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Design of Synthetic Autonomous VH Domain Libraries and Structural Analysis of a VH Domain Bound to Vascular Endothelial Growth Factor.
J.Mol.Biol., 425, 2013
6D3O
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BU of 6d3o by Molmil
Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with HH4, an alpha/beta-Peptide with Irregular Secondary Structure
Descriptor: HH4 alpha/beta-Peptide, Vascular endothelial growth factor A
Authors:Thomas, N.C, Forest, K.T, Gellman, S.H.
Deposit date:2018-04-16
Release date:2019-04-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:High-Resolution Structures for a Complex Between a Non-Helical Foldamer and VEGF
To Be Published
2FJG
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BU of 2fjg by Molmil
Structure of the G6 Fab, a phage derived Fab fragment, in complex with VEGF
Descriptor: Fab heavy chain, Fab light chain, SULFATE ION, ...
Authors:Wiesmann, C.
Deposit date:2006-01-02
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.
J.Biol.Chem., 281, 2006
1ILR
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BU of 1ilr by Molmil
CRYSTAL STRUCTURE OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST
Descriptor: INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
Authors:Schreuder, H.A, Rondeau, J.-M, Tardif, C.
Deposit date:1994-06-20
Release date:1995-02-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.
Eur.J.Biochem., 227, 1995
2GPN
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BU of 2gpn by Molmil
100 K STRUCTURE OF GLYCOGEN PHOSPHORYLASE AT 2.0 ANGSTROMS RESOLUTION
Descriptor: GLYCOGEN PHOSPHORYLASE B
Authors:Gregoriou, M, Noble, M.E.M, Watson, K.A, Garman, E.F, Krulle, T.M, De La Fuente, C, Fleet, G.W.J, Oikonomakos, N.G, Johnson, L.N.
Deposit date:1998-03-26
Release date:1998-07-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein Sci., 7, 1998
3OYR
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BU of 3oyr by Molmil
Crystal structure of polyprenyl synthase from Caulobacter crescentus CB15 complexed with calcium and isoprenyl diphosphate
Descriptor: CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, PYROPHOSPHATE 2-, ...
Authors:Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-09-23
Release date:2010-10-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
3P8L
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BU of 3p8l by Molmil
Crystal structure of polyprenyl synthase from Enterococcus faecalis V583
Descriptor: Geranyltranstransferase
Authors:Patskovsky, Y, Toro, R, Dickey, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-10-14
Release date:2010-11-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IRP
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BU of 1irp by Molmil
SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
Descriptor: INTERLEUKIN-1 RECEPTOR ANTAGONIST
Authors:Stockman, B.J, Scahill, T.A, Strakalaitis, N.A.
Deposit date:1994-10-18
Release date:1995-02-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of human interleukin-1 receptor antagonist protein.
FEBS Lett., 349, 1994
2F3S
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BU of 2f3s by Molmil
Crystal Structure of the glycogen phosphorylase B / ethyl-N-(beta-D-glucopyranosyl)oxamate complex
Descriptor: Glycogen phosphorylase, muscle form, N-[ethoxy(oxo)acetyl]-beta-D-glucopyranosylamine, ...
Authors:Oikonomakos, N.G, Leonidas, D.D.
Deposit date:2005-11-22
Release date:2006-05-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.
Bioorg.Med.Chem., 14, 2006
1IOB
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BU of 1iob by Molmil
INTERLEUKIN-1 BETA FROM JOINT X-RAY AND NMR REFINEMENT
Descriptor: INTERLEUKIN-1 BETA
Authors:Shaanan, B, Clore, G.M.
Deposit date:1996-03-14
Release date:1996-08-17
Last modified:2024-05-01
Method:SOLUTION NMR (2 Å), X-RAY DIFFRACTION
Cite:Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science, 257, 1992
3P41
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BU of 3p41 by Molmil
Crystal structure of polyprenyl synthetase from pseudomonas fluorescens pf-5 complexed with magnesium and isoprenyl pyrophosphate
Descriptor: CHLORIDE ION, DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, ...
Authors:Patskovsky, Y, Toro, R, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-10-05
Release date:2010-10-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
3QKI
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BU of 3qki by Molmil
Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
Descriptor: Glucose-6-phosphate isomerase
Authors:Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC)
Deposit date:2011-02-01
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
TO BE PUBLISHED
2G9U
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BU of 2g9u by Molmil
The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethyl-1-(3-phenylpropyl)-piperidine-3,4-diol and phosphate
Descriptor: (3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL, Glycogen phosphorylase, muscle form, ...
Authors:Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E.
Deposit date:2006-03-07
Release date:2007-01-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
J.Med.Chem., 49, 2006
2G9V
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BU of 2g9v by Molmil
The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethylpiperidine-3,4-diol and phosphate
Descriptor: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, Glycogen phosphorylase, muscle form, ...
Authors:Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E.
Deposit date:2006-03-07
Release date:2007-01-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
J.Med.Chem., 49, 2006
3QTK
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BU of 3qtk by Molmil
The crystal structure of chemically synthesized VEGF-A
Descriptor: ACETATE ION, GLYCEROL, Vascular endothelial growth factor A, ...
Authors:Mandal, K, Kent, S.B.H.
Deposit date:2011-02-22
Release date:2011-07-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Total chemical synthesis of biologically active vascular endothelial growth factor.
Angew.Chem.Int.Ed.Engl., 50, 2011
1JIQ
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BU of 1jiq by Molmil
Crystal Structure of Human Autocrine Motility Factor
Descriptor: autocrine motility factor
Authors:Tanaka, N, Haga, A, Uemura, H, Akiyama, H, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T.
Deposit date:2001-07-02
Release date:2002-06-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
2FOR
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BU of 2for by Molmil
Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
Descriptor: Geranyltranstransferase, ISOPENTYL PYROPHOSPHATE, PHOSPHATE ION
Authors:Minasov, G, Brunzelle, J.S, Shuvalova, L, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-01-13
Release date:2006-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
To be Published
1K08
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BU of 1k08 by Molmil
Crystallographic Binding Study of 10 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase b
Descriptor: Glycogen Phosphorylase, N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine, PYRIDOXAL-5'-PHOSPHATE
Authors:Oikonomakos, N.G, Kosmopoulou, M, Zographos, S.E, Leonidas, D.D, Chrysina, E.D, Somsak, L, Nagy, V, Praly, J.P, Docsa, T, Toth, B, Gergely, P.
Deposit date:2001-09-18
Release date:2001-10-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
Eur.J.Biochem., 269, 2002
3PH7
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BU of 3ph7 by Molmil
Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate
Descriptor: Farnesyl pyrophosphate synthase, GERANYLGERANYL DIPHOSPHATE
Authors:Wernimont, A.K, Dunford, J, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC)
Deposit date:2010-11-03
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.
J.Biol.Chem., 286, 2011
3POK
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BU of 3pok by Molmil
Interleukin-1-beta LBT L3 Mutant
Descriptor: Interleukin-1 beta
Authors:Barthelmes, K, Reynolds, A.M, Peisach, E, Jonker, H.R.A, DeNunzio, N.J, Allen, K.N, Imperiali, B, Schwalbe, H.
Deposit date:2010-11-22
Release date:2011-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Engineering encodable lanthanide-binding tags into loop regions of proteins.
J.Am.Chem.Soc., 133, 2011
3Q2Q
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BU of 3q2q by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from Corynebacterium glutamicum complexed with calcium and isoprenyl diphosphate
Descriptor: CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, ...
Authors:Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Poulter, C.D, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-12-20
Release date:2011-01-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
2H8O
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BU of 2h8o by Molmil
The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens
Descriptor: Geranyltranstransferase
Authors:Zhang, R, Xu, X, Gu, J, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-06-07
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens
To be Published
3PDE
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BU of 3pde by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from Lactobacillus brevis atcc 367 complexed with isoprenyl diphosphate and magnesium
Descriptor: DIMETHYLALLYL DIPHOSPHATE, Farnesyl-diphosphate synthase, GLYCEROL, ...
Authors:Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-10-22
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013

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