2G9V

The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethylpiperidine-3,4-diol and phosphate

Summary for 2G9V

Entry DOI	10.2210/pdb2g9v/pdb
Related	2g9q 2g9r 2g9u
Descriptor	Glycogen phosphorylase, muscle form, PHOSPHATE ION, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ... (4 entities in total)
Functional Keywords	glycogen phosphorylase, catalytic site, rational inhibitor design, transferase
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	1
Total formula weight	97856.43
Authors	Oikonomakos, N.G.,Tiraidis, C.,Leonidas, D.D.,Zographos, S.E. (deposition date: 2006-03-07, release date: 2007-01-16, Last modification date: 2023-11-15)
Primary citation	Oikonomakos, N.G.,Tiraidis, C.,Leonidas, D.D.,Zographos, S.E.,Kristiansen, M.,Jessen, C.U.,Norskov-Lauritsen, L.,Agius, L. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. J.Med.Chem., 49:5687-5701, 2006 Cited by PubMed: 16970395 DOI: 10.1021/jm060496g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation