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3NKV
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BU of 3nkv by Molmil
Crystal structure of Rab1b covalently modified with AMP at Y77
Descriptor: ADENOSINE MONOPHOSPHATE, BARIUM ION, MAGNESIUM ION, ...
Authors:Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A.
Deposit date:2010-06-21
Release date:2010-08-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science, 329, 2010
2L0X
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BU of 2l0x by Molmil
Solution structure of the 21 kDa GTPase RHEB bound to GDP
Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Stoll, R, Heumann, R, Berghaus, C, Kock, G.
Deposit date:2010-07-19
Release date:2010-08-04
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Ras homolog enriched in brain (Rheb) enhances apoptotic signaling.
J.Biol.Chem., 285, 2010
3OES
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BU of 3oes by Molmil
Crystal structure of the small GTPase RhebL1
Descriptor: GTPase RhebL1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Nedyalkova, L, Zhong, N, Tempel, W, Tong, Y, Shen, L, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-08-13
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structure of the small GTPase RhebL1
to be published
2KWI
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BU of 2kwi by Molmil
RalB-RLIP76 (RalBP1) complex
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RalA-binding protein 1, ...
Authors:Fenwick, R.B, Campbell, L.J, Rajasekar, K, Prasannan, S, Nietlispach, D, Camonis, J, Owen, D, Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
3NC0
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BU of 3nc0 by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II)
Descriptor: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBY
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BU of 3nby by Molmil
Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBZ
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BU of 3nbz by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I)
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3K9L
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BU of 3k9l by Molmil
Allosteric modulation of H-Ras GTPase
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Fetics, S, Young, M, Buhrman, G, Mattos, C.
Deposit date:2009-10-15
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Allosteric modulation of H-Ras GTPase
To be Published
3OIW
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BU of 3oiw by Molmil
H-RasG12V with allosteric switch in the "on" state
Descriptor: ACETATE ION, CALCIUM ION, GTPase HRas, ...
Authors:Kumar, S, Buhrman, G, Mattos, C.
Deposit date:2010-08-20
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase.
J.Biol.Chem., 286, 2011
3OIV
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BU of 3oiv by Molmil
H-RasG12V with allosteric switch in the "off" state
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
Authors:Buhrman, G, Mattos, C.
Deposit date:2010-08-20
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.837 Å)
Cite:Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase.
J.Biol.Chem., 286, 2011
3OIU
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BU of 3oiu by Molmil
H-RasQ61L with allosteric switch in the "on" state
Descriptor: ACETATE ION, CALCIUM ION, GTPase HRas, ...
Authors:Buhrman, G, Mattos, C.
Deposit date:2010-08-20
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase.
J.Biol.Chem., 286, 2011
3L8Y
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BU of 3l8y by Molmil
Complex of Ras with cyclen
Descriptor: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3L8Z
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BU of 3l8z by Molmil
H-Ras wildtype new crystal form
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3Q3J
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BU of 3q3j by Molmil
Crystal structure of plexin A2 RBD in complex with Rnd1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A2, ...
Authors:Wang, H, Tempel, W, Tong, Y, Guan, X, Shen, L, Buren, L, Zhang, N, Wernimont, A.K, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-12-21
Release date:2011-01-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Crystal structure of plexin A2 RBD in complex with Rnd1
to be published
3PIR
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BU of 3pir by Molmil
Crystal structure of M-RasD41E in complex with GppNHp (type 1)
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras
Authors:Muraoka, S, Matsumoto, K, Shima, F, Hu, L, Ijiri, Y, Hirai, R, Liao, J, Kataoka, T.
Deposit date:2010-11-07
Release date:2011-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of M-RasD41E in complex with GppNHp (type 1)
To be Published
3PIT
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BU of 3pit by Molmil
Crystal structure of M-RasD41E in complex with GppNHp (type 2)
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras
Authors:Muraoka, S, Matsumoto, K, Shima, F, Hu, L, Ijiri, Y, Hirai, R, Liao, J, Kataoka, T.
Deposit date:2010-11-08
Release date:2011-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of M-RasD41E in complex with GppNHp (type 2)
To be Published
3MSX
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BU of 3msx by Molmil
Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ...
Authors:Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S.
Deposit date:2010-04-29
Release date:2011-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
To be Published
2YC2
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BU of 2yc2 by Molmil
Intraflagellar Transport Complex 25-27 from Chlamydomonas
Descriptor: CALCIUM ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, SMALL RAB-RELATED GTPASE
Authors:Bhogaraju, S, Taschner, M, Lorentzen, E.
Deposit date:2011-03-11
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.588 Å)
Cite:Crystal Structure of the Intraflagellar Transport Complex 25/27.
Embo J., 30, 2011
2YC4
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BU of 2yc4 by Molmil
Intraflagellar Transport Complex 25-27 from Chlamydomonas
Descriptor: CALCIUM ION, CHLORIDE ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, ...
Authors:Bhogaraju, S, Taschner, M, Lorentzen, E.
Deposit date:2011-03-11
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Intraflagellar Transport Complex 25/27.
Embo J., 30, 2011
3QBT
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BU of 3qbt by Molmil
Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp
Descriptor: Inositol polyphosphate 5-phosphatase OCRL-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hou, X, Hagemann, N, Schoebel, S, Blankenfeldt, W, Goody, R.S, Erdmann, K.S, Itzen, A.
Deposit date:2011-01-14
Release date:2011-03-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1.
Embo J., 30, 2011
2YIN
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BU of 2yin by Molmil
STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1.
Descriptor: DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1
Authors:Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D.
Deposit date:2011-05-16
Release date:2011-05-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors.
J.Biol.Chem., 286, 2011
2Y8E
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BU of 2y8e by Molmil
Crystal structure of D. melanogaster Rab6 GTPase bound to GMPPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-PROTEIN 6, ...
Authors:Walden, M, Edwards, T.A.
Deposit date:2011-02-04
Release date:2011-07-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structure of the Drosophila Melanogaster Rab6 Gtpase at 1.4 A Resolution
Acta Crystallogr.,Sect.F, 67, 2011
3T06
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BU of 3t06 by Molmil
Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA
Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Bielnicki, J.A, Derewenda, U, Derewenda, Z.S.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
J.Biol.Chem., 286, 2011
3SUA
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BU of 3sua by Molmil
Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-B1, ...
Authors:Bell, C.H, Aricescu, A.R, Jones, E.Y, Siebold, C.
Deposit date:2011-07-11
Release date:2011-09-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.39 Å)
Cite:A Dual Binding Mode for RhoGTPases in Plexin Signalling.
Plos Biol., 9, 2011

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PDB entries from 2024-11-13

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