PDB: 1329 件ウェブページステータス検索Chemie searchBIRD

---

3K34	Human carbonic anhydrase II with a sulfonamide inhibitor 分子名称: (4-SULFAMOYL-PHENYL)-THIOCARBAMIC ACID O-(2-THIOPHEN-3-YL-ETHYL) ESTER, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Behnke, C.A, Le Trong, I, Merritt, E.A, Teller, D.C, Stenkamp, R.E. 登録日 2009-10-01 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Atomic resolution studies of carbonic anhydrase II. Acta Crystallogr.,Sect.D, 66, 2010
3K7K	Crystal structure of the complex between Carbonic Anhydrase II and anions 分子名称: Carbonic anhydrase 2, MERCURY (II) ION, ZINC ION, ... 著者 Temperini, C. 登録日 2009-10-13 公開日 2010-01-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct-An inhibitor mimicking the sulfonamide and urea binding to the enzyme Bioorg.Med.Chem.Lett., 20, 2010
3KIG	Mutant carbonic anhydrase II in complex with an azide and an alkyne 分子名称: 2-azido-N-(2-sulfanylethyl)ethanamide, 3-ethynylbenzenesulfonamide, Carbonic anhydrase 2, ... 著者 Schulze-Wischeler, J, Niehage, N.U, Heine, A, Klebe, G. 登録日 2009-11-02 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry. Chemistry, 17, 2011
3KKX	Neutron structure of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Fisher, S.Z, Langan, P.A. 登録日 2009-11-06 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 Neutron structure of human carbonic anhydrase II: implications for proton transfer. Biochemistry, 49, 2010
3KLD	PTPRG CNTN4 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin 4, Receptor-type tyrosine-protein phosphatase gamma 著者 Bouyain, S. 登録日 2009-11-07 公開日 2009-12-22 最終更新日 2021-03-31 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Proc.Natl.Acad.Sci.USA, 107, 2010
3KNE	Carbonic Anhydrase II H64C mutant in complex with an in situ formed triazole 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, N-[(S)-(1-{2-oxo-2-[(3-sulfanylpropyl)amino]ethyl}-1H-1,2,3-triazol-5-yl)(phenyl)methyl]-4-sulfamoylbenzamide, ... 著者 Schulze-Wischeler, J, Heine, A, Klebe, G. 登録日 2009-11-12 公開日 2011-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry. Chemistry, 17, 2011
3KOK	Crystal structure of cobalt (II) human carbonic anhydrase II at pH 8.5 分子名称: COBALT (II) ION, Carbonic anhydrase 2 著者 Avvaru, B.S. 登録日 2009-11-13 公開日 2010-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II. Arch.Biochem.Biophys., 502, 2010
3KOI	Crystal structure of cobalt (III) human carbonic anhydrase II at pH 6.0 分子名称: COBALT (III) ION, Carbonic anhydrase 2 著者 Avvaru, B.S. 登録日 2009-11-13 公開日 2010-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II. Arch.Biochem.Biophys., 502, 2010
3KON	Crystal structure of cobalt (II) human carbonic anhydrase II at pH 11.0 分子名称: COBALT (II) ION, Carbonic anhydrase 2 著者 Avvaru, B.S. 登録日 2009-11-13 公開日 2010-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II. Arch.Biochem.Biophys., 502, 2010
3KS3	High resolution structure of Human Carbonic Anhydrase II at 0.9 A 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 Avvaru, B.S. 登録日 2009-11-20 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 A short, strong hydrogen bond in the active site of human carbonic anhydrase II. Biochemistry, 49, 2010
3KWA	Polyamines inhibit carbonic anhydrases 分子名称: Carbonic anhydrase 2, MERCURY (II) ION, SPERMINE, ... 著者 Temperini, C. 登録日 2009-12-01 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule J.Med.Chem., 53, 2010
3L14	Human Carbonic Anhydrase II complexed with Althiazide 分子名称: 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Quirit, J.G, Robbins, A, Genis, C, Tu, C, Silverman, D.N, McKenna, R. 登録日 2009-12-10 公開日 2011-01-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 The Promiscuous Nature of Althiazide in Adducts with CA II and CA IX Mimic To be Published
3LXE	Human Carbonic Anhydrase I in complex with topiramate 分子名称: Carbonic anhydrase 1, ZINC ION, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate 著者 Alterio, V, De Simone, G, Monti, S.M, Truppo, E. 登録日 2010-02-25 公開日 2010-07-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. Org.Biomol.Chem., 2010
3M04	Carbonic Anhydrase II in complex with novel sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, ZINC ION, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G, Sandner, N.U. 登録日 2010-03-02 公開日 2011-05-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural investigation and inhibitor studies on Carbonic Anhydrase II To be Published
2X7T	Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors. 分子名称: (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ... 著者 Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L. 登録日 2010-03-03 公開日 2010-03-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-Steroidal Inhibitors. Biochemistry, 49, 2010
2X7S	Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors. 分子名称: (13ALPHA,14BETA,17ALPHA)-3-HYDROXY-2-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL SULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ... 著者 Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L. 登録日 2010-03-03 公開日 2010-03-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Nonsteroidal Inhibitors. Biochemistry, 49, 2010
2X7U	Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors. 分子名称: (9BETA,14BETA,17BETA)-17-HYDROXY-2-METHOXYESTRA-1,3,5(10)-TRIEN-3-YL SULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ... 著者 Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L. 登録日 2010-03-03 公開日 2010-03-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-Steroidal Inhibitors. Biochemistry, 49, 2010
3M14	Carbonic Anhydrase II in complex with novel sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, N-[(2Z)-1,3-thiazolidin-2-ylidene]sulfamide, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G, Sandner, N.U. 登録日 2010-03-04 公開日 2011-05-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural investigation and inhibitor studies on Carbonic Anhydrase II To be Published
3M1J	The crystal structure of a NAMI A-Carbonic Anhydrase II adduct discloses the mode of action of this novel anticancer metallodrug 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, IMIDAZOLE, ... 著者 Temperini, C, Messori, L. 登録日 2010-03-05 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins Chemmedchem, 5, 2010
3M1W	Carbonic Anhyrdase II mutant W5CH64C with closed disulfide bond in complex with sulfate 分子名称: Carbonic anhydrase 2, SULFATE ION, ZINC ION 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-05 公開日 2011-05-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Mutational Study on Carbonic Anhydrase II To be Published
3M1K	Carbonic Anhydrase in complex with fragment 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 1-hydroxy-2-sulfanylpyridinium, Carbonic anhydrase 2, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-05 公開日 2010-11-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry. Chemmedchem, 5, 2010
3M1Q	Carbonic Anhydrase II mutant W5C-H64C with opened disulfide bond 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-05 公開日 2011-05-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Mutational study on Carbonic Anhydrase II To be Published
3M2X	Carbonic Anhydrase II in complex with novel sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, N-[(R)-[(3,4-dimethoxyphenyl)amino](phenoxy)methyl]sulfamide, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-08 公開日 2011-05-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural investigation and inhibitor studies on Carbonic Anhydrase II To be Published
3M2Y	Carbonic Anhydrase II in complex with novel sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-08 公開日 2011-05-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Structural investigation and inhibitor stuies on Carbonic Anhydrase II To be Published
3M2N	Crystal structure of human carbonic anhydrase isozyme II with 4-{2-[N-(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide 分子名称: 4-{2-[(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Golovenko, D. 登録日 2010-03-08 公開日 2011-02-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012

<78910111213141516171819202122>