3K34

Human carbonic anhydrase II with a sulfonamide inhibitor

Summary for 3K34

Entry DOI	10.2210/pdb3k34/pdb
Descriptor	Carbonic anhydrase 2, 4-(HYDROXYMERCURY)BENZOIC ACID, ZINC ION, ... (6 entities in total)
Functional Keywords	carbonic anhydrase, atomic resolution, sulfonamide inhibitor, disease mutation, lyase, metal-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	30311.92
Authors	Behnke, C.A.,Le Trong, I.,Merritt, E.A.,Teller, D.C.,Stenkamp, R.E. (deposition date: 2009-10-01, release date: 2010-05-12, Last modification date: 2023-09-06)
Primary citation	Behnke, C.A.,Le Trong, I.,Godden, J.W.,Merritt, E.A.,Teller, D.C.,Bajorath, J.,Stenkamp, R.E. Atomic resolution studies of carbonic anhydrase II. Acta Crystallogr.,Sect.D, 66:616-627, 2010 Cited by PubMed: 20445237 DOI: 10.1107/S0907444910006554 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.9 Å)

Structure validation