3K7K
Crystal structure of the complex between Carbonic Anhydrase II and anions
Summary for 3K7K
| Entry DOI | 10.2210/pdb3k7k/pdb |
| Related | 1BV3 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
| Functional Keywords | inorganic anion, trithiocarbonate, x ray, carbonic anhydrase ii, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29665.28 |
| Authors | Temperini, C. (deposition date: 2009-10-13, release date: 2010-01-26, Last modification date: 2023-11-01) |
| Primary citation | Temperini, C.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct-An inhibitor mimicking the sulfonamide and urea binding to the enzyme Bioorg.Med.Chem.Lett., 20:474-478, 2010 Cited by PubMed: 20005709DOI: 10.1016/j.bmcl.2009.11.124 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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