8J83
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![BU of 8j83 by Molmil](/molmil-images/mine/8j83) | Crystal structure of formate dehydrogenase from Methylorubrum extorquens AM1 | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Kobayashi, A, Taketa, M, Sowa, K, Kano, K, Higuchi, Y, Ogata, H. | Deposit date: | 2023-04-29 | Release date: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and function relationship of formate dehydrogenases: an overview of recent progress. Iucrj, 10, 2023
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8J82
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![BU of 8j82 by Molmil](/molmil-images/mine/8j82) | GaHNL-12gen (artificial S-hydroxynitrile lyase generated by GAOptimizer) | Descriptor: | S-hydroxynitrile lyase | Authors: | Ozawa, H, Unno, I, Sekine, R, Ito, S, Nakano, S. | Deposit date: | 2023-04-29 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Development of evolutionary algorithm-based protein redesign method Cell Rep Phys Sci, 5, 2024
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8J81
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![BU of 8j81 by Molmil](/molmil-images/mine/8j81) | MDM2 bound with a peptoid | Descriptor: | (2S)-2-[[(2S)-2-[(6-chloranyl-1H-indol-3-yl)methyl-[(2S)-2-[[(2S)-2-[ethanoyl-(phenylmethyl)amino]propanoyl]-methyl-amino]propanoyl]amino]propanoyl]-methyl-amino]-N-(3,3-dimethylbutyl)-N-[(2S)-1-oxidanylidene-1-piperazin-1-yl-propan-2-yl]propanamide, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2 | Authors: | Yokomine, M, Fukuda, Y, Ago, H, Matsuura, H, Ueno, G, Nagatoishi, S, Yamamoto, M, Tsumoto, K, Jumpei, M, Sando, S. | Deposit date: | 2023-04-28 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A structural and physicochemical study of how a peptoid binds to a protein To Be Published
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8J80
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![BU of 8j80 by Molmil](/molmil-images/mine/8j80) | Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7Y
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![BU of 8j7y by Molmil](/molmil-images/mine/8j7y) | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7X
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![BU of 8j7x by Molmil](/molmil-images/mine/8j7x) | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7W
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![BU of 8j7w by Molmil](/molmil-images/mine/8j7w) | Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7V
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![BU of 8j7v by Molmil](/molmil-images/mine/8j7v) | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7U
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![BU of 8j7u by Molmil](/molmil-images/mine/8j7u) | Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7T
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![BU of 8j7t by Molmil](/molmil-images/mine/8j7t) | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7R
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![BU of 8j7r by Molmil](/molmil-images/mine/8j7r) | Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused) | Descriptor: | Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION | Authors: | Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I. | Deposit date: | 2023-04-28 | Release date: | 2023-08-02 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun, 14, 2023
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8J7L
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![BU of 8j7l by Molmil](/molmil-images/mine/8j7l) | crystal structure of SulE mutant | Descriptor: | Alpha/beta fold hydrolase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Liu, B, He, J, Ran, T, Wang, W. | Deposit date: | 2023-04-27 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | crystal structure of SulE mutant To Be Published
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8J7K
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![BU of 8j7k by Molmil](/molmil-images/mine/8j7k) | crystal structure of SulE mutant | Descriptor: | Alpha/beta fold hydrolase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Liu, B, He, J, Ran, T, Wang, W. | Deposit date: | 2023-04-27 | Release date: | 2023-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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8J7J
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![BU of 8j7j by Molmil](/molmil-images/mine/8j7j) | crystal structure of SulE mutant | Descriptor: | Alpha/beta fold hydrolase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Liu, B, He, J, Ran, T, Wang, W. | Deposit date: | 2023-04-27 | Release date: | 2023-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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8J7I
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![BU of 8j7i by Molmil](/molmil-images/mine/8j7i) | crystal structure of SulE mutant | Descriptor: | Alpha/beta fold hydrolase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Liu, B, He, J, Ran, T, Wang, W. | Deposit date: | 2023-04-27 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | crystal structure of SulE mutant To Be Published
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8J7G
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![BU of 8j7g by Molmil](/molmil-images/mine/8j7g) | crystal structure of SulE mutant | Descriptor: | Alpha/beta fold hydrolase, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Liu, B, He, J, Ran, T, Wang, W. | Deposit date: | 2023-04-27 | Release date: | 2023-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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8J7C
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![BU of 8j7c by Molmil](/molmil-images/mine/8j7c) | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.88A with an arsenic ion bound at Cys57 | Descriptor: | ARSENIC, Triosephosphate isomerase | Authors: | Kuaprasert, B, Attarataya, J, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Mungthin, M, Leelayoova, S, Choowongkomon, K, Leartsakulpanich, U. | Deposit date: | 2023-04-27 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors To be published
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8J79
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![BU of 8j79 by Molmil](/molmil-images/mine/8j79) | |
8J74
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![BU of 8j74 by Molmil](/molmil-images/mine/8j74) | Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, dimeric state | Descriptor: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), CHOLESTEROL HEMISUCCINATE, HEXADECANE, ... | Authors: | Gao, Y, Qiu, Y, Zhao, Y. | Deposit date: | 2023-04-27 | Release date: | 2024-04-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Transport mechanism of presynaptic high-affinity choline uptake by CHT1. Nat.Struct.Mol.Biol., 31, 2024
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8J6Y
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![BU of 8j6y by Molmil](/molmil-images/mine/8j6y) | |
8J6X
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![BU of 8j6x by Molmil](/molmil-images/mine/8j6x) | |
8J6V
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![BU of 8j6v by Molmil](/molmil-images/mine/8j6v) | |
8J6R
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![BU of 8j6r by Molmil](/molmil-images/mine/8j6r) | Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex | Descriptor: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | Deposit date: | 2023-04-26 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
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8J6Q
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![BU of 8j6q by Molmil](/molmil-images/mine/8j6q) | Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex | Descriptor: | (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ... | Authors: | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | Deposit date: | 2023-04-26 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
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8J6P
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![BU of 8j6p by Molmil](/molmil-images/mine/8j6p) | Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ... | Authors: | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | Deposit date: | 2023-04-26 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
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