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1QNX
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BU of 1qnx by Molmil
Ves v 5, an allergen from Vespula vulgaris venom
Descriptor: SODIUM ION, VES V 5
Authors:Henriksen, A, Gajhede, M, Spangfort, M.D.
Deposit date:1999-10-25
Release date:2000-10-26
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Major Venom Allergen of Yellow Jackets, Ves V 5: Structural Characterization of a Pathogenesis-Related Protein Superfamily.
Proteins: Struct.,Funct., Genet., 45, 2001
1T6D
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BU of 1t6d by Molmil
MIRAS phasing of the Aquifex aeolicus Ppx/GppA phosphatase: crystal structure of the type II variant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, exopolyphosphatase
Authors:Kristensen, O, Laurberg, M, Liljas, A, Kastrup, J.S, Gajhede, M.
Deposit date:2004-05-06
Release date:2004-08-03
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family
Biochemistry, 43, 2004
5ZNY
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BU of 5zny by Molmil
Structure of mDR3_DD-C363G with MBP tag
Descriptor: Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION
Authors:Yin, X, Jin, T.
Deposit date:2018-04-11
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
5ZNZ
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BU of 5znz by Molmil
Structure of mDR3 DD with MBP tag mutant-I387V
Descriptor: Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION
Authors:Jin, T, Yin, X.
Deposit date:2018-04-12
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
8R8Q
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BU of 8r8q by Molmil
Lysosomal peptide transporter
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosylated lysosomal membrane protein, Major facilitator superfamily domain-containing protein 1
Authors:Jungnickel, K.E.J, Loew, C.
Deposit date:2023-11-29
Release date:2024-05-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.
Nat.Cell Biol., 2024
3MC2
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BU of 3mc2 by Molmil
Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase
Descriptor: Inhibitor of Carbonic Anhydrase
Authors:Eckenroth, B.E, Mason, A.B, Everse, S.J.
Deposit date:2010-03-26
Release date:2010-07-28
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure and evolution of the murine inhibitor of carbonic anhydrase: A member of the transferrin superfamily.
Protein Sci., 19, 2010
1W4F
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BU of 1w4f by Molmil
Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE
Authors:Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R.
Deposit date:2004-07-23
Release date:2005-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
2YCD
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BU of 2ycd by Molmil
Structure of a novel Glutathione Transferase from Agrobacterium tumefaciens.
Descriptor: GLUTATHIONE S-TRANSFERASE, PHOSPHATE ION, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Skopelitou, K, Dhavala, P, Papageorgiou, A.C, Labrou, N.E.
Deposit date:2011-03-13
Release date:2012-03-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Glutathione Transferase from Agrobacterium Tumefaciens Reveals a Novel Class of Bacterial Gst Superfamily.
Plos One, 7, 2012
1W4G
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BU of 1w4g by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state folding transitions
Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE
Authors:Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
Deposit date:2004-07-23
Release date:2005-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
1W4J
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BU of 1w4j by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
Descriptor: PYRUVATE DEHYDROGENASE E2
Authors:Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
Deposit date:2004-07-23
Release date:2005-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family.
J. Mol. Biol., 353, 2005
5VYY
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BU of 5vyy by Molmil
Structure of human Hsp90-alpha bound to resorcinylic inhibitor BnIm
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Heat shock protein HSP 90-alpha, ...
Authors:Que, N.S, Gewirth, D.T.
Deposit date:2017-05-26
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.
J. Med. Chem., 61, 2018
1SVY
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BU of 1svy by Molmil
SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE
Descriptor: CALCIUM ION, SEVERIN, SODIUM ION
Authors:Puius, Y.A, Fedorov, E.V, Eichinger, L, Sullivan, M, Schleicher, M, Almo, S.C.
Deposit date:1998-08-10
Release date:1999-08-10
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry, 39, 2000
6UT2
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BU of 6ut2 by Molmil
3D structure of the leiomodin/tropomyosin binding interface
Descriptor: Leiomodin-2, Tropomyosin alpha-1 chain chimeric peptide
Authors:Tolkatchev, D, Smith, G.E, Helms, G.L, Cort, J.R, Kostyukova, A.S.
Deposit date:2019-10-29
Release date:2020-09-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Leiomodin creates a leaky cap at the pointed end of actin-thin filaments.
Plos Biol., 18, 2020
5DIM
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BU of 5dim by Molmil
Mutant toxin in 'native' space group
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
Authors:Parker, M.W, Gorman, M.A, Lawrence, S.L.
Deposit date:2015-09-01
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of mutant toxin at 3.32 Angstrom resolution
To Be Published
3H7H
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BU of 3h7h by Molmil
Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273)
Descriptor: BETA-MERCAPTOETHANOL, Transcription elongation factor SPT4, Transcription elongation factor SPT5, ...
Authors:Wenzel, S, Wohrl, B.M, Rosch, P, Martins, B.M.
Deposit date:2009-04-27
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
Biochem.J., 425, 2010
7LSL
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BU of 7lsl by Molmil
Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H63A, crystallized in the presence of Ni(II)
Descriptor: HEME C, NICKEL (II) ION, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-18
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond
To Be Published
7LSJ
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BU of 7lsj by Molmil
Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H63A, crystallized in the presence of Cu(II)
Descriptor: CALCIUM ION, COPPER (II) ION, HEME C, ...
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-18
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond
To Be Published
7LSN
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BU of 7lsn by Molmil
Ni-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H63A, crystallized in the presence of Ni(II)
Descriptor: HEME C, NICKEL (II) ION, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-18
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond
To Be Published
7LV4
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BU of 7lv4 by Molmil
Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H97A, crystallized in the presence of Cu(II)
Descriptor: CALCIUM ION, COPPER (II) ION, HEME C, ...
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond
To Be Published
5DHL
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BU of 5dhl by Molmil
Crystal structure of Toxin, mutant N197W
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Perfringolysin O
Authors:Parker, M.W, Gorman, M.A, Lawrence, S.L.
Deposit date:2015-08-31
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structure of mutant toxin
To Be Published
7LMX
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BU of 7lmx by Molmil
A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE
Descriptor: Integrin inhibitor
Authors:Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
Deposit date:2021-02-06
Release date:2022-08-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
7LMV
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BU of 7lmv by Molmil
SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6
Descriptor: Integrin inhibitor
Authors:Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
Deposit date:2021-02-05
Release date:2022-08-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
5GOU
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BU of 5gou by Molmil
Structure of a 16-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign
Descriptor: Ferritin heavy chain
Authors:Zhang, S, Zang, J, Wang, W, Wang, H, Zhao, G.
Deposit date:2016-07-29
Release date:2017-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues.
Angew. Chem. Int. Ed. Engl., 55, 2016
8YX9
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BU of 8yx9 by Molmil
CD40 in complex with Dacetuzumab Fab
Descriptor: Dacetuzumab, Heavy chain, light chain, ...
Authors:Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K.
Deposit date:2024-04-02
Release date:2024-05-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
8YX1
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BU of 8yx1 by Molmil
CD40 in complex with Bleselumab Fab
Descriptor: Bleselumab, heavy chain, light chain, ...
Authors:Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K.
Deposit date:2024-04-01
Release date:2024-05-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024

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