PDB: 1288 resultsInfo pagesStatus searchChemie searchBIRD

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6HLQ	Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HTQ	Stringent response control by a bifunctional RelA enzyme in the presence and absence of the ribosome Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Wilson, D.N, Abdelshahid, M. Deposit date: 2018-10-04 Release date: 2019-10-23 Last modified: 2020-09-30 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel. Cell Rep, 32, 2020
6HKO	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-07 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6JCY	Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2019-01-30 Release date: 2019-05-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.106 Å) Cite: Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res., 47, 2019
8DPX	Preligand association structure of DR5 Descriptor: Tumor necrosis factor receptor superfamily member 10B Authors: Du, G, Zhao, L, Chou, J.J. Deposit date: 2022-07-17 Release date: 2023-02-15 Method: SOLUTION NMR Cite: Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation. Cell Res., 33, 2023
5WQ6	Crystal Structure of hMNDA-PYD with MBP tag Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MBP tagged hMNDA-PYD, ... Authors: Jin, T.C, Xiao, T.S. Deposit date: 2016-11-23 Release date: 2017-02-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.648 Å) Cite: Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
4MB6	Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. Descriptor: Adenine phosphoribosyltransferase, SODIUM ION Authors: Pavithra, G.C, Kim, J, Hegde, R.P, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-08-19 Release date: 2013-09-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis To be published
4DN1	Crystal structure of an ENOLASE (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate Descriptor: CHLORIDE ION, FORMIC ACID, Isomerase/lactonizing enzyme, ... Authors: Vetting, M.W, Toro, R, Bhosle, R, Bouvier, J.T, Wasserman, S.R, Morisco, L.L, Sojitra, S, Al Obaidi, N.F, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) Deposit date: 2012-02-08 Release date: 2012-03-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal structure of an enolase (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate to be published
3KY9	Autoinhibited Vav1 Descriptor: Proto-oncogene vav, ZINC ION Authors: Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B. Deposit date: 2009-12-04 Release date: 2010-02-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.731 Å) Cite: Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 Cell(Cambridge,Mass.), 140, 2010
4DXC	Crystal structure of the engineered MBP TEM-1 fusion protein RG13, C2 space group Descriptor: Maltose-binding periplasmic protein, Beta-lactamase TEM chimera, ZINC ION Authors: van den Akker, F, Ke, W. Deposit date: 2012-02-27 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of an Engineered beta-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation. Plos One, 7, 2012
4LZA	Crystal structure of adenine phosphoribosyltransferase from Thermoanaerobacter pseudethanolicus ATCC 33223, NYSGRC Target 029700. Descriptor: Adenine phosphoribosyltransferase, CHLORIDE ION Authors: Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-07-31 Release date: 2013-08-14 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Crystal structure of adenine phosphoribosyltransferase from Thermoanaerobacter pseudethanolicus ATCC 33223, NYSGRC Target 029700. To be Published
7XI2	Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with phosphate Descriptor: ACETATE ION, Adenine phosphoribosyltransferase, CHLORIDE ION, ... Authors: Yadav, P, Kushwaha, G.S, Bhavesh, N.S. Deposit date: 2022-04-11 Release date: 2023-04-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with phosphate To Be Published
7XMN	Structure of SARS-CoV-2 ORF8 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltodextrin-binding protein, ... Authors: Chen, X, Xu, W. Deposit date: 2022-04-26 Release date: 2023-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Glycosylated, Lipid-Binding, CDR-Like Domains of SARS-CoV-2 ORF8 Indicate Unique Sites of Immune Regulation. Microbiol Spectr, 11, 2023
6USM	Structure of nuclease domain of human parvovirus B19 non-structural protein 1 in complex with zinc Descriptor: Maltodextrin-binding protein, Non-structural protein NS1, ZINC ION, ... Authors: Tewary, S.K. Deposit date: 2019-10-28 Release date: 2020-12-09 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.37 Å) Cite: B19 Parvovirus Non-structural protein 1 in complex with zinc To Be Published
7CJX	UDP-glucuronosyltransferase 2B15 C-terminal domain-L446S Descriptor: L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B15 Authors: Wang, C.Y, Zhang, L. Deposit date: 2020-07-14 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.986414 Å) Cite: Structure of UDP-glucuronosyltransferase 2B15 C-terminal domain L446S at 1.99 Angstroms resolution To Be Published
7FV2	PanDDA analysis group deposition -- PHIP in complex with Z445899798 Descriptor: N-(2-methoxyethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FV1	PanDDA analysis group deposition -- PHIP in complex with Z4912742920 Descriptor: PH-interacting protein, tert-butyl [3-({[4-(furan-2-carbonyl)piperazine-1-carbonyl]amino}methyl)phenyl]carbamate Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVI	PanDDA analysis group deposition -- PHIP in complex with Z183306756 Descriptor: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FVG	PanDDA analysis group deposition -- PHIP in complex with Z992453336 Descriptor: N-(4-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVL	PanDDA analysis group deposition -- PHIP in complex with Z4140355932 Descriptor: N-{[(2S)-5,5-dimethyl-1,4-dioxan-2-yl]methyl}-4-(3-hydroxybenzoyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVJ	PanDDA analysis group deposition -- PHIP in complex with Z4913873236 Descriptor: (2S)-4-(furan-2-carbonyl)-2-methyl-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVA	PanDDA analysis group deposition -- PHIP in complex with Z4913872963 Descriptor: (2S)-N-(cyclopropylmethyl)-4-(furan-2-carbonyl)-2-methylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FV9	PanDDA analysis group deposition -- PHIP in complex with Z1004253138 Descriptor: 4-(5-methylfuran-2-carbonyl)-N-[(thiophen-2-yl)methyl]piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.17 Å) Cite: PanDDA analysis group deposition To Be Published
7FVQ	PanDDA analysis group deposition -- PHIP in complex with Z68576046 Descriptor: N-butyl-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVM	PanDDA analysis group deposition -- PHIP in complex with Z1590917771 Descriptor: 4-(furan-2-carbonyl)-N-(1,2-oxazol-3-yl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.26 Å) Cite: PanDDA analysis group deposition To Be Published

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