5H87
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![BU of 5h87 by Molmil](/molmil-images/mine/5h87) | Crystal structure of mRojoA mutant - P63H - W143S | Descriptor: | mRojoA fluorescent protein | Authors: | Pandelieva, A.T, Tremblay, V, Sarvan, S, Chica, R.A, Couture, J.-F. | Deposit date: | 2015-12-23 | Release date: | 2016-01-27 | Last modified: | 2016-03-02 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Brighter Red Fluorescent Proteins by Rational Design of Triple-Decker Motif. Acs Chem.Biol., 11, 2016
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5KO4
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![BU of 5ko4 by Molmil](/molmil-images/mine/5ko4) | Bromodomain from Trypanosoma brucei Tb427.10.8150 | Descriptor: | Putative uncharacterized protein, SULFATE ION | Authors: | El Bakkouri, M, Walker, J.R, Hou, C.F.D, Lin, Y.H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2016-06-29 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Bromodomain from Trypanosoma brucei Tb427.10.8150 To be published
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5SS9
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![BU of 5ss9 by Molmil](/molmil-images/mine/5ss9) | |
5SPK
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![BU of 5spk by Molmil](/molmil-images/mine/5spk) | |
4LWO
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![BU of 4lwo by Molmil](/molmil-images/mine/4lwo) | Crystal structure of PRMT6 | Descriptor: | Arginine N-methyltransferase, putative | Authors: | Zhu, Y, Wang, C, Shi, Y, Teng, M. | Deposit date: | 2013-07-28 | Release date: | 2014-02-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei Plos One, 9, 2014
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4LSM
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![BU of 4lsm by Molmil](/molmil-images/mine/4lsm) | |
3I3G
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![BU of 3i3g by Molmil](/molmil-images/mine/3i3g) | Crystal Structure of Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A | Descriptor: | N-acetyltransferase | Authors: | Qiu, W, Wernimont, A.K, Marino, K, Zhang, A.Z, Ma, D, Lin, Y.H, Mackenzie, F, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, J Ferguson, M.A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2009-06-30 | Release date: | 2009-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A To be Published
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4LWP
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![BU of 4lwp by Molmil](/molmil-images/mine/4lwp) | Crystal structure of PRMT6-SAH | Descriptor: | Arginine N-methyltransferase, putative, IODIDE ION, ... | Authors: | Zhu, Y, Wang, C, Shi, Y, Teng, M. | Deposit date: | 2013-07-28 | Release date: | 2014-02-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.353 Å) | Cite: | Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei Plos One, 9, 2014
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5TVF
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![BU of 5tvf by Molmil](/molmil-images/mine/5tvf) | Crystal structure of Trypanosoma brucei AdoMetDC/prozyme heterodimer in complex with inhibitor CGP 40215 | Descriptor: | 1,4-DIAMINOBUTANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM, ... | Authors: | Phillips, M.A, Volkov, O.A, Chen, Z, Tomchick, D.R. | Deposit date: | 2016-11-08 | Release date: | 2017-01-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog. Elife, 5, 2016
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3UMQ
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![BU of 3umq by Molmil](/molmil-images/mine/3umq) | Crystal structure of peptidoglycan recognition protein-S complexed with butyric acid at 2.2 A resolution | Descriptor: | GLYCEROL, Peptidoglycan recognition protein 1, butanoic acid | Authors: | Pandey, N, Sharma, P, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2011-11-14 | Release date: | 2012-07-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site Arch.Biochem.Biophys., 529, 2013
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1O2D
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![BU of 1o2d by Molmil](/molmil-images/mine/1o2d) | |
3KJS
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![BU of 3kjs by Molmil](/molmil-images/mine/3kjs) | Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex | Descriptor: | 1,2-ETHANEDIOL, Dihydrofolate reductase-thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Schormann, N, Senkovich, O, Chattopadhyay, D. | Deposit date: | 2009-11-03 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase. Bioorg.Med.Chem., 18, 2010
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5RLJ
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![BU of 5rlj by Molmil](/molmil-images/mine/5rlj) | PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with Z1407673036 | Descriptor: | (2S)-2-phenylpropane-1-sulfonamide, Helicase, PHOSPHATE ION, ... | Authors: | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-09-16 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.879 Å) | Cite: | Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun, 12, 2021
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5RMH
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![BU of 5rmh by Molmil](/molmil-images/mine/5rmh) | PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with Z1101755952 | Descriptor: | Helicase, PHOSPHATE ION, ZINC ION, ... | Authors: | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-09-16 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.021 Å) | Cite: | Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun, 12, 2021
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1HPL
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![BU of 1hpl by Molmil](/molmil-images/mine/1hpl) | |
5RLT
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![BU of 5rlt by Molmil](/molmil-images/mine/5rlt) | PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with Z53116498 | Descriptor: | 3-(2-methyl-1H-benzimidazol-1-yl)propanamide, Helicase, PHOSPHATE ION, ... | Authors: | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-09-16 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun, 12, 2021
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3V7T
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![BU of 3v7t by Molmil](/molmil-images/mine/3v7t) | |
4DSH
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![BU of 4dsh by Molmil](/molmil-images/mine/4dsh) | Crystal structure of reduced UDP-Galactopyranose mutase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Dhatwalia, R, Singh, H, Tanner, J.J. | Deposit date: | 2012-02-18 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation. Biochemistry, 51, 2012
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4DSG
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![BU of 4dsg by Molmil](/molmil-images/mine/4dsg) | Crystal Structure of oxidized UDP-Galactopyranose mutase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... | Authors: | Singh, H, Dhatwalia, R, Tanner, J.J. | Deposit date: | 2012-02-18 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation. Biochemistry, 51, 2012
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4BES
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![BU of 4bes by Molmil](/molmil-images/mine/4bes) | Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate and phosphocholine | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, PHOSPHOCHOLINE, PHOSPHOCHOLINE TRANSFERASE ANKX, ... | Authors: | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | Deposit date: | 2013-03-12 | Release date: | 2013-04-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain. Embo J., 32, 2013
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2PTZ
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![BU of 2ptz by Molmil](/molmil-images/mine/2ptz) | Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation | Descriptor: | 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ... | Authors: | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | Deposit date: | 2007-05-08 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. Febs J., 274, 2007
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2PU0
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![BU of 2pu0 by Molmil](/molmil-images/mine/2pu0) | Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-in conformation | Descriptor: | 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ... | Authors: | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | Deposit date: | 2007-05-08 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. Febs J., 274, 2007
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2PTW
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![BU of 2ptw by Molmil](/molmil-images/mine/2ptw) | Crystal Structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV | Descriptor: | 1,2-ETHANEDIOL, Enolase, SULFATE ION, ... | Authors: | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | Deposit date: | 2007-05-08 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. Febs J., 274, 2007
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2PTX
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![BU of 2ptx by Molmil](/molmil-images/mine/2ptx) | Crystal Structure of the T. brucei enolase complexed with sulphate in closed conformation | Descriptor: | 1,2-ETHANEDIOL, Enolase, SULFATE ION, ... | Authors: | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | Deposit date: | 2007-05-08 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. Febs J., 274, 2007
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2PU1
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![BU of 2pu1 by Molmil](/molmil-images/mine/2pu1) | Crystal Structure of the T. brucei enolase complexed with Fluoro-phosphonoacetohydroxamate (FPAH) | Descriptor: | 1,2-ETHANEDIOL, Enolase, ZINC ION, ... | Authors: | Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G. | Deposit date: | 2007-05-08 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. Febs J., 274, 2007
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