8ZBZ
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![BU of 8zbz by Molmil](/molmil-images/mine/8zbz) | SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, ... | Authors: | Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X. | Deposit date: | 2024-04-28 | Release date: | 2024-05-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.71 Å) | Cite: | An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike. Cell Rep, 43, 2024
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8Y6B
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![BU of 8y6b by Molmil](/molmil-images/mine/8y6b) | Structure of human LGI1-ADAM22 complex in space group P212121 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... | Authors: | Liu, H, Xu, F. | Deposit date: | 2024-02-02 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Structure of human LGI1-ADAM22 complex in space group P212121 To Be Published
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8XGC
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![BU of 8xgc by Molmil](/molmil-images/mine/8xgc) | Structure of yeast replisome associated with FACT and histone hexamer, Composite map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | Authors: | Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y. | Deposit date: | 2023-12-15 | Release date: | 2024-02-14 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Parental histone transfer caught at the replication fork. Nature, 627, 2024
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8Z1L
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![BU of 8z1l by Molmil](/molmil-images/mine/8z1l) | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant atomoxetine in an outward-open state at resolution of 3.4 angstrom. | Descriptor: | (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2024-04-11 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 2024
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8VKA
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![BU of 8vka by Molmil](/molmil-images/mine/8vka) | Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 9c | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2024-01-08 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors. J.Med.Chem., 67, 2024
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7DSX
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![BU of 7dsx by Molmil](/molmil-images/mine/7dsx) | Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide, ... | Authors: | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | Deposit date: | 2021-01-03 | Release date: | 2021-06-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and mechanism of the human NHE1-CHP1 complex. Nat Commun, 12, 2021
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8VKO
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![BU of 8vko by Molmil](/molmil-images/mine/8vko) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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9FSV
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![BU of 9fsv by Molmil](/molmil-images/mine/9fsv) | Yeast 20S proteasome with human beta2i (1-53) in complex with epoxyketone inhibitor 42 | Descriptor: | (2S)-N-[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]-2-(2-morpholin-4-ylethanoylamino)-4-oxidanyl-butanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | Deposit date: | 2024-06-22 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites to be published
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8XSY
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![BU of 8xsy by Molmil](/molmil-images/mine/8xsy) | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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9FEK
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![BU of 9fek by Molmil](/molmil-images/mine/9fek) | |
8ZBY
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![BU of 8zby by Molmil](/molmil-images/mine/8zby) | SARS-CoV-2 Omicron BA.1 spike trimer (x2-4P) in complex with 3 D1F6 Fabs (0 RBD up) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, ... | Authors: | Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X. | Deposit date: | 2024-04-28 | Release date: | 2024-05-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike. Cell Rep, 43, 2024
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8Y36
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![BU of 8y36 by Molmil](/molmil-images/mine/8y36) | cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190. | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | Authors: | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | Deposit date: | 2024-01-28 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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8WB4
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![BU of 8wb4 by Molmil](/molmil-images/mine/8wb4) | Structure of PSII-ACPII supercomplex from cryptophyte algae | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ... | Authors: | Li, X.Y, Mao, Z.Y, Shen, J.R, Han, G.Y. | Deposit date: | 2023-09-08 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.47 Å) | Cite: | Structure and distinct supramolecular organization of a PSII-ACPII dimer from a cryptophyte alga Chroomonas placoidea. Nat Commun, 15, 2024
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8VKK
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![BU of 8vkk by Molmil](/molmil-images/mine/8vkk) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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8X55
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![BU of 8x55 by Molmil](/molmil-images/mine/8x55) | BA.2.86 Spike Trimer with T356K mutation (3 RBD down) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-11-16 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8YOP
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![BU of 8yop by Molmil](/molmil-images/mine/8yop) | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | Deposit date: | 2024-03-13 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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9ENK
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![BU of 9enk by Molmil](/molmil-images/mine/9enk) | L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with L-phenylalanine | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, PHENYLALANINE, ... | Authors: | Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H. | Deposit date: | 2024-03-13 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and enzyme engineering of the broad substrate spectrum L-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum to be published
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7DDQ
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![BU of 7ddq by Molmil](/molmil-images/mine/7ddq) | Structure of RC-LH1-PufX from Rhodobacter veldkampii | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ... | Authors: | Bracun, L, Yamagata, A, Shirouzu, M, Liu, L.N. | Deposit date: | 2020-10-29 | Release date: | 2021-06-30 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM structure of the photosynthetic RC-LH1-PufX supercomplex at 2.8-angstrom resolution. Sci Adv, 7, 2021
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8XQB
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![BU of 8xqb by Molmil](/molmil-images/mine/8xqb) | Mature virion portal vertex of bacteriophage lambda | Descriptor: | Capsid decoration protein, Head completion protein, Head-tail connector protein FII, ... | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-05 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.07 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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9ATW
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![BU of 9atw by Molmil](/molmil-images/mine/9atw) | Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus | Descriptor: | Phenol-soluble modulin alpha 1 peptide | Authors: | Hansen, K.H, Byeon, C.H, Liu, Q, Drace, T, Boesen, T, Conway, J.F, Andreasen, M, Akbey, U. | Deposit date: | 2024-02-27 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of biofilm-forming functional amyloid PSM alpha 1 from Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 121, 2024
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8Y1E
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![BU of 8y1e by Molmil](/molmil-images/mine/8y1e) | 3up-TM conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8VKM
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![BU of 8vkm by Molmil](/molmil-images/mine/8vkm) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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8XB8
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![BU of 8xb8 by Molmil](/molmil-images/mine/8xb8) | The structure of ASFV A137R | Descriptor: | A137R | Authors: | Li, C, Song, H, Gao, G.F. | Deposit date: | 2023-12-06 | Release date: | 2024-01-31 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | African swine fever virus A137R assembles into a dodecahedron cage. J.Virol., 98, 2024
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8WEY
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![BU of 8wey by Molmil](/molmil-images/mine/8wey) | PSI-LHCI of the red alga Cyanidium caldarium RK-1 (NIES-2137) | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{R} )-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | Authors: | Kato, K, Hamaguchi, T, Nakajima, Y, Kawakami, K, Yonekura, K, Shen, J.R, Nagao, R. | Deposit date: | 2023-09-19 | Release date: | 2024-02-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (1.92 Å) | Cite: | The structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs. Proc.Natl.Acad.Sci.USA, 121, 2024
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9B36
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![BU of 9b36 by Molmil](/molmil-images/mine/9b36) | Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map. | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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